Pentose Phosphate Pathway
"Pentose Phosphate Pathway" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An oxidative decarboxylation process that converts GLUCOSE-6-PHOSPHATE to D-ribose-5-phosphate via 6-phosphogluconate. The pentose product is used in the biosynthesis of NUCLEIC ACIDS. The generated energy is stored in the form of NADPH. This pathway is prominent in tissues which are active in the synthesis of FATTY ACIDS and STEROIDS.
| Descriptor ID |
D010427
|
| MeSH Number(s) |
G02.111.158.875 G03.191.875 G03.295.693 G03.493.695
|
| Concept/Terms |
Pentose Phosphate Pathway- Pentose Phosphate Pathway
- Pathway, Pentose Phosphate
- Pathways, Pentose Phosphate
- Pentose Phosphate Pathways
- Pentose Phosphate Shunt
- Pentose Phosphate Shunts
- Shunt, Pentose Phosphate
- Shunts, Pentose Phosphate
- Pentose Shunt
- Pentose Shunts
- Shunt, Pentose
- Shunts, Pentose
- Pentose-Phosphate Pathway
- Pathway, Pentose-Phosphate
- Pathways, Pentose-Phosphate
- Pentose-Phosphate Pathways
- Pentosephosphate Shunt
- Pentosephosphate Shunts
- Shunt, Pentosephosphate
- Shunts, Pentosephosphate
- Hexose Monophosphate Shunt
- Hexose Monophosphate Shunts
- Shunt, Hexose Monophosphate
- Shunts, Hexose Monophosphate
- Pentosephosphate Pathway
- Pathway, Pentosephosphate
- Pathways, Pentosephosphate
- Pentosephosphate Pathways
|
Below are MeSH descriptors whose meaning is more general than "Pentose Phosphate Pathway".
Below are MeSH descriptors whose meaning is more specific than "Pentose Phosphate Pathway".
This graph shows the total number of publications written about "Pentose Phosphate Pathway" by people in this website by year, and whether "Pentose Phosphate Pathway" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2015 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
| 2019 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Pentose Phosphate Pathway" by people in Profiles.
-
Hlavaty SI, Salcido KN, Pniewski KA, Mukha D, Ma W, Kannan T, Cassel J, Srikanth YVV, Liu Q, Kossenkov A, Salvino JM, Chen Q, Schug ZT. ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis. Cell Rep. 2024 12 24; 43(12):114988.
-
Rohlhill J, Gerald Har JR, Antoniewicz MR, Papoutsakis ET. Improving synthetic methylotrophy via dynamic formaldehyde regulation of pentose phosphate pathway genes and redox perturbation. Metab Eng. 2020 01; 57:247-255.
-
Diaz CAC, Bennett RK, Papoutsakis ET, Antoniewicz MR. Deletion of four genes in Escherichia coli enables preferential consumption of xylose and secretion of glucose. Metab Eng. 2019 03; 52:168-177.
-
Bennett RK, Gonzalez JE, Whitaker WB, Antoniewicz MR, Papoutsakis ET. Expression of heterologous non-oxidative pentose phosphate pathway from Bacillus methanolicus and phosphoglucose isomerase deletion improves methanol assimilation and metabolite production by a synthetic Escherichia coli methylotroph. Metab Eng. 2018 01; 45:75-85.
-
Guo L, Shestov AA, Worth AJ, Nath K, Nelson DS, Leeper DB, Glickson JD, Blair IA. Inhibition of Mitochondrial Complex II by the Anticancer Agent Lonidamine. J Biol Chem. 2016 Jan 01; 291(1):42-57.
-
Li J, Ward KM, Zhang D, Dayanandam E, Denittis AS, Prendergast GC, Ayene IS. A bioactive probe of the oxidative pentose phosphate cycle: novel strategy to reverse radioresistance in glucose deprived human colon cancer cells. Toxicol In Vitro. 2013 Feb; 27(1):367-77.
-
Crown SB, Indurthi DC, Ahn WS, Choi J, Papoutsakis ET, Antoniewicz MR. Resolving the TCA cycle and pentose-phosphate pathway of Clostridium acetobutylicum ATCC 824: Isotopomer analysis, in vitro activities and expression analysis. Biotechnol J. 2011 Mar; 6(3):300-5.
-
Silverton SF, Matsumoto H, DeBolt K, Reginato A, Shapiro IM. Pentose phosphate shunt metabolism by cells of the chick growth cartilage. Bone. 1989; 10(1):45-51.