"Clathrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The main structural coat protein of COATED VESICLES which play a key role in the intracellular transport between membranous organelles. Each molecule of clathrin consists of three light chains (CLATHRIN LIGHT CHAINS) and three heavy chains (CLATHRIN HEAVY CHAINS) that form a structure called a triskelion. Clathrin also interacts with cytoskeletal proteins.
| Descriptor ID |
D002966
|
| MeSH Number(s) |
D12.776.543.990.200
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clathrin".
Below are MeSH descriptors whose meaning is more specific than "Clathrin".
This graph shows the total number of publications written about "Clathrin" by people in this website by year, and whether "Clathrin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 3 | 1 | 4 |
| 1998 | 1 | 1 | 2 |
| 1999 | 0 | 1 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 2 | 1 | 3 |
| 2003 | 0 | 1 | 1 |
| 2005 | 1 | 3 | 4 |
| 2006 | 2 | 0 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 1 | 2 | 3 |
| 2009 | 2 | 0 | 2 |
| 2010 | 1 | 1 | 2 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Clathrin" by people in Profiles.
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Martinez-Martin N, Viejo-Borbolla A, Mart?n R, Blanco S, Benovic JL, Thelen M, Alcam? A. Herpes simplex virus enhances chemokine function through modulation of receptor trafficking and oligomerization. Nat Commun. 2015 Jan 27; 6:6163.
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Marszalowicz GP, Snook AE, Magee MS, Merlino D, Berman-Booty LD, Waldman SA. GUCY2C lysosomotropic endocytosis delivers immunotoxin therapy to metastatic colorectal cancer. Oncotarget. 2014 Oct 15; 5(19):9460-71.
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Tian X, Kang DS, Benovic JL. ?-arrestins and G protein-coupled receptor trafficking. Handb Exp Pharmacol. 2014; 219:173-86.
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Kang DS, Tian X, Benovic JL. ?-Arrestins and G protein-coupled receptor trafficking. Methods Enzymol. 2013; 521:91-108.
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Luo Y, Zhan Y, Keen JH. Arf6 regulation of Gyrating-clathrin. Traffic. 2013 Jan; 14(1):97-106.
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Morcavallo A, Genua M, Palummo A, Kletvikova E, Jiracek J, Brzozowski AM, Iozzo RV, Belfiore A, Morrione A. Insulin and insulin-like growth factor II differentially regulate endocytic sorting and stability of insulin receptor isoform A. J Biol Chem. 2012 Mar 30; 287(14):11422-36.
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Castorino JJ, Deborde S, Deora A, Schreiner R, Gallagher-Colombo SM, Rodriguez-Boulan E, Philp NJ. Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia. Traffic. 2011 Apr; 12(4):483-98.
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Li G, Shi Y, Huang H, Zhang Y, Wu K, Luo J, Sun Y, Lu J, Benovic JL, Zhou N. Internalization of the human nicotinic acid receptor GPR109A is regulated by G(i), GRK2, and arrestin3. J Biol Chem. 2010 Jul 16; 285(29):22605-18.
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Mundell SJ, Matharu AL, Nisar S, Palmer TM, Benovic JL, Kelly E. Deletion of the distal COOH-terminus of the A2B adenosine receptor switches internalization to an arrestin- and clathrin-independent pathway and inhibits recycling. Br J Pharmacol. 2010 Feb 01; 159(3):518-33.
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Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL. Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking. J Biol Chem. 2009 Oct 23; 284(43):29860-72.