"Cytotoxins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Substances that are toxic to cells; they may be involved in immunity or may be contained in venoms. These are distinguished from CYTOSTATIC AGENTS in degree of effect. Some of them are used as CYTOTOXIC ANTIBIOTICS. The mechanism of action of many of these are as ALKYLATING AGENTS or MITOSIS MODULATORS.
| Descriptor ID |
D003603
|
| MeSH Number(s) |
D27.888.569.213
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Cytotoxins".
Below are MeSH descriptors whose meaning is more specific than "Cytotoxins".
This graph shows the total number of publications written about "Cytotoxins" by people in this website by year, and whether "Cytotoxins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2009 | 2 | 0 | 2 |
| 2012 | 1 | 2 | 3 |
| 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Cytotoxins" by people in Profiles.
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Cecen B, Keles D, Oktay G, Kozaci LD. Effects of simvastatin on matrix metalloproteinase regulation in IL-1?-induced SW1353 cells. Chem Biol Interact. 2019 Sep 01; 310:108730.
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Lawrence YR, Vikram B, Dignam JJ, Chakravarti A, Machtay M, Freidlin B, Takebe N, Curran WJ, Bentzen SM, Okunieff P, Coleman CN, Dicker AP. NCI-RTOG translational program strategic guidelines for the early-stage development of radiosensitizers. J Natl Cancer Inst. 2013 Jan 02; 105(1):11-24.
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Shore N, Mason M, de Reijke TM. New developments in castrate-resistant prostate cancer. BJU Int. 2012 Jun; 109 Suppl 6:22-32.
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Conesa C, Doss MX, Antzelevitch C, Sachinidis A, Sancho J, Carrodeguas JA. Identification of specific pluripotent stem cell death--inducing small molecules by chemical screening. Stem Cell Rev Rep. 2012 Mar; 8(1):116-27.
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Das U, Sakagami H, Chu Q, Wang Q, Kawase M, Selvakumar P, Sharma RK, Dimmock JR. 3,5-Bis(benzylidene)-1-[4-2-(morpholin-4-yl)ethoxyphenylcarbonyl]-4-piperidone hydrochloride: a lead tumor-specific cytotoxin which induces apoptosis and autophagy. Bioorg Med Chem Lett. 2010 Feb 01; 20(3):912-7.
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Das S, Das U, Selvakumar P, Sharma RK, Balzarini J, De Clercq E, Moln?r J, Serly J, Bar?th Z, Schatte G, Bandy B, Gorecki DK, Dimmock JR. 3,5-Bis(benzylidene)-4-oxo-1-phosphonopiperidines and related diethyl esters: Potent cytotoxins with multi-drug-resistance reverting properties. ChemMedChem. 2009 Nov; 4(11):1831-40.
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Arafat HA, Katakam AK, Chipitsyna G, Gong Q, Vancha AR, Gabbeta J, Dafoe DC. Osteopontin protects the islets and beta-cells from interleukin-1 beta-mediated cytotoxicity through negative feedback regulation of nitric oxide. Endocrinology. 2007 Feb; 148(2):575-84.
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Al-Saif NM, O'Neill GL, Magee JT, Brazier JS, Duerden BI. PCR-ribotyping and pyrolysis mass spectrometry fingerprinting of environmental and hospital isolates of Clostridium difficile. J Med Microbiol. 1998 Feb; 47(2):117-21.