"Leukotriene B4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
| Descriptor ID |
D007975
|
| MeSH Number(s) |
D10.251.355.255.100.450.411 D10.251.355.310.166.887.411 D23.469.050.175.450.415
|
| Concept/Terms |
Leukotriene B4- Leukotriene B4
- Leukotriene B-4
- B-4, Leukotriene
- Leukotriene B 4
- LTB4
|
Below are MeSH descriptors whose meaning is more general than "Leukotriene B4".
Below are MeSH descriptors whose meaning is more specific than "Leukotriene B4".
This graph shows the total number of publications written about "Leukotriene B4" by people in this website by year, and whether "Leukotriene B4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Leukotriene B4" by people in Profiles.
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Marvar PJ, Hendy EB, Cruise TD, Walas D, DeCicco D, Vadigepalli R, Schwaber JS, Waki H, Murphy D, Paton JF. Systemic leukotriene B4 receptor antagonism lowers arterial blood pressure and improves autonomic function in the spontaneously hypertensive rat. J Physiol. 2016 10 15; 594(20):5975-5989.
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Sener G, Sehirli O, Velioglu-Og?n? A, Cetinel S, Gedik N, Caner M, Sakarcan A, Yegen BC. Montelukast protects against renal ischemia/reperfusion injury in rats. Pharmacol Res. 2006 Jul; 54(1):65-71.
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Tong WG, Ding XZ, Talamonti MS, Bell RH, Adrian TE. LTB4 stimulates growth of human pancreatic cancer cells via MAPK and PI-3 kinase pathways. Biochem Biophys Res Commun. 2005 Sep 30; 335(3):949-56.
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Setty BN, Stuart MJ. Eicosanoids in sickle cell disease: potential relevance of neutrophil leukotriene B4 to disease pathophysiology. J Lab Clin Med. 2002 Feb; 139(2):80-9.
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Pi F, Hotter G, Closa D, Prats N, Fern?ndez-Cruz L, Badosa F, Gelpi E, Rosell?-Catafau J. Differential effect of nitric oxide inhibition as a function of preservation period in pancreas transplantation. Dig Dis Sci. 1997 May; 42(5):962-71.
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Kane GC, Tollino M, Pollice M, Kim CJ, Cohn J, Murray JJ, Dworski R, Sheller J, Fish JE, Peters SP. Insights into IgE-mediated lung inflammation derived from a study employing a 5-lipoxygenase inhibitor. Prostaglandins. 1995 Jul; 50(1):1-18.
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Kim CJ, Kane GC, Zangrilli JG, Cho SK, Koh YY, Peters SP. Eosinophils recruited to the lung by segmental antigen challenge show a reduced chemotactic response to leukotriene B4. Prostaglandins. 1994 May; 47(5):393-403.
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Hotter G, Closa D, Pi F, Rosell?-Catafau J, Bulbena O, Badosa F, Fern?ndez-Cruz L, Gelp? E. Arachidonate metabolism in ischemia-reperfusion associated with pancreas transplantation. J Lipid Mediat Cell Signal. 1994 Mar; 9(2):135-43.