"Ligases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A class of enzymes that catalyze the formation of a bond between two substrate molecules, coupled with the hydrolysis of a pyrophosphate bond in ATP or a similar energy donor. (Dorland, 28th ed) EC 6.
| Descriptor ID |
D008025
|
| MeSH Number(s) |
D08.811.464
|
| Concept/Terms |
Ligases- Ligases
- Synthetases
- Synthetase
|
Below are MeSH descriptors whose meaning is more general than "Ligases".
Below are MeSH descriptors whose meaning is more specific than "Ligases".
This graph shows the total number of publications written about "Ligases" by people in this website by year, and whether "Ligases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2009 | 1 | 0 | 1 |
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Below are the most recent publications written about "Ligases" by people in Profiles.
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Natori Y, Tagami K, Murakami K, Yoshida S, Tanigawa O, Moh Y, Masuda K, Wada T, Suzuki S, Nanamiya H, Tozawa Y, Kawamura F. Transcription activity of individual rrn operons in Bacillus subtilis mutants deficient in (p)ppGpp synthetase genes, relA, yjbM, and ywaC. J Bacteriol. 2009 Jul; 191(14):4555-61.
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Vecchione A, Marchese A, Henry P, Rotin D, Morrione A. The Grb10/Nedd4 complex regulates ligand-induced ubiquitination and stability of the insulin-like growth factor I receptor. Mol Cell Biol. 2003 May; 23(9):3363-72.
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Harty RN, Brown ME, McGettigan JP, Wang G, Jayakar HR, Huibregtse JM, Whitt MA, Schnell MJ. Rhabdoviruses and the cellular ubiquitin-proteasome system: a budding interaction. J Virol. 2001 Nov; 75(22):10623-9.
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Peruzzi F, Prisco M, Morrione A, Valentinis B, Baserga R. Anti-apoptotic signaling of the insulin-like growth factor-I receptor through mitochondrial translocation of c-Raf and Nedd4. J Biol Chem. 2001 Jul 13; 276(28):25990-6.
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Rebbeck TR, Walker AH, Zeigler-Johnson C, Weisburg S, Martin AM, Nathanson KL, Wein AJ, Malkowicz SB. Association of HPC2/ELAC2 genotypes and prostate cancer. Am J Hum Genet. 2000 Oct; 67(4):1014-9.
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Morrione A, Plant P, Valentinis B, Staub O, Kumar S, Rotin D, Baserga R. mGrb10 interacts with Nedd4. J Biol Chem. 1999 Aug 20; 274(34):24094-9.
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Harvey KF, Harvey NL, Michael JM, Parasivam G, Waterhouse N, Alnemri ES, Watters D, Kumar S. Caspase-mediated cleavage of the ubiquitin-protein ligase Nedd4 during apoptosis. J Biol Chem. 1998 May 29; 273(22):13524-30.
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Dabbagh O, Brismar J, Gascon GG, Ozand PT. The clinical spectrum of biotin-treatable encephalopathies in Saudi Arabia. Brain Dev. 1994 Nov; 16 Suppl:72-80.
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Cocchetto DM, Bjornsson TD. Studies in rats on in vitro inhibition and in vivo activity of vitamin-K-dependent carboxylation. Haemostasis. 1986; 16(5):321-36.