Necrosis

"Necrosis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The pathological process occurring in cells that are dying from irreparable injuries. It is caused by the progressive, uncontrolled action of degradative ENZYMES, leading to MITOCHONDRIAL SWELLING, nuclear flocculation, and cell lysis. It is distinct it from APOPTOSIS, which is a normal, regulated cellular process.

Descriptor ID	D009336
MeSH Number(s)	C23.550.717 G04.146.638
Concept/Terms	Necrosis Necrosis Necroses

Below are MeSH descriptors whose meaning is more general than "Necrosis".

Diseases [C]
Pathological Conditions, Signs and Symptoms [C23]
Pathologic Processes [C23.550]
Necrosis [C23.550.717]
Biological Sciences [G]
Cell Physiological Phenomena [G04]
Cell Death [G04.146]
Necrosis [G04.146.638]

Below are MeSH descriptors whose meaning is related to "Necrosis".

Below are MeSH descriptors whose meaning is more specific than "Necrosis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Necrosis" by people in this website by year, and whether "Necrosis" was a major or minor topic of these publications.

Bar chart showing 90 publications over 28 distinct years, with a maximum of 8 publications in 2008 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	2	2
1997	0	1	1
1998	0	3	3
1999	0	2	2
2000	0	2	2
2001	0	2	2
2002	0	2	2
2003	0	1	1
2004	0	5	5
2005	0	4	4
2006	0	4	4
2007	0	6	6
2008	0	8	8
2009	0	4	4
2010	0	2	2
2011	0	2	2
2013	0	5	5
2014	0	1	1
2015	0	2	2
2016	0	3	3
2017	0	2	2
2018	1	4	5
2019	0	3	3
2020	0	8	8
2021	0	5	5
2022	0	2	2
2023	0	1	1
2024	2	1	3

Below are the most recent publications written about "Necrosis" by people in Profiles.

Arango SD, Flynn JC, Zeitlin JH, Weir TB, Miller AJ. Xylazine-Associated Necrotic Upper-Extremity Wounds: A Single Hospital System's Experience with 82 Patients and 125 Wounds. J Bone Joint Surg Am. 2025 Feb 05; 107(3):279-286.

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Arango SD, Weir TB, Miller AJ, Osterman MN. Skin necrosis following digital wart intralesional injection of cantharidin. Dermatol Online J. 2024 Oct 15; 30(5).

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Jones VM, Nelson JA, Sevilimedu V, Le T, Allen RJ, Mehrara BJ, Barrio AV, Capko DM, Heerdt AS, Tadros AB, Gemignani ML, Morrow M, Sacchini V, Moo TA. Impact of Mastectomy Flap Necrosis on Patient-Reported Quality-of-Life Measures After Nipple-Sparing Mastectomy: A Preliminary Analysis. Ann Surg Oncol. 2024 Oct; 31(10):6795-6803.

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Moo TA, Nelson JA, Sevilimedu V, Charyn J, Le TV, Allen RJ, Mehrara BJ, Barrio AV, Capko DM, Pilewskie M, Heerdt AS, Tadros AB, Gemignani ML, Morrow M, Sacchini V. Strategies to avoid mastectomy skin-flap necrosis during nipple-sparing mastectomy. Br J Surg. 2023 06 12; 110(7):831-838.

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Blomain E, Berta S, Hug N, Giao D, Meola A, Binkley M, Hui C, Churilla T, Shahsavari N, Desai K, Chang S, Soltys S, Pollom E. Radiotherapy for Brain Metastases from Thyroid Cancer: An Institutional and National Retrospective Cohort Study. Thyroid. 2022 07; 32(7):781-788.

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Slijepcevic AA, Young G, Shinn J, Cannady SB, Hanasono M, Old M, Grewal JS, Ghanem T, Ducic Y, Curry JM, Wax MK. Success and Outcomes Following a Second Salvage Attempt for Free Flap Compromise in Patients Undergoing Head and Neck Reconstruction. JAMA Otolaryngol Head Neck Surg. 2022 06 01; 148(6):555-560.

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Luginbuhl AJ, Hobelmann K, Rodin J, Shukla S, Rodeck U, Linnenbach A. Synthetic Triterpenoid RTA-408: Limits Radiation Damage to Normal Tissue. Laryngoscope. 2022 06; 132(6):1196-1204.

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Holmes I, Shinn B, Mitsuhashi S, Boortalary T, Bashir M, Kowalski T, Loren D, Kumar A, Schlachterman A, Chiang A. Prediction and management of bleeding during endoscopic necrosectomy for pancreatic walled-off necrosis: results of a large retrospective cohort at a tertiary referral center. Gastrointest Endosc. 2022 03; 95(3):482-488.

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Stassen PMC, de Jonge PJF, Bruno MJ, Koch AD, Trindade AJ, Benias PC, Sejpal DV, Siddiqui UD, Chapman CG, Villa E, Tharian B, Inamdar S, Hwang JH, Barakat MT, Andalib I, Gaidhane M, Sarkar A, Shahid H, Tyberg A, Binmoeller K, Watson RR, Nett A, Schlag C, Abdelhafez M, Friedrich-Rust M, Schlachterman A, Chiang AL, Loren D, Kowalski T, Kahaleh M. Safety and efficacy of a novel resection system for direct endoscopic necrosectomy of walled-off pancreas necrosis: a prospective, international, multicenter trial. Gastrointest Endosc. 2022 03; 95(3):471-479.

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Ahmed ST, Nuni O, Tirumanisetty P, Zhao Y, Alhasson H, Mubasher M, Alweis R. Skin Necrosis Caused by Levamisole-Adulterated Cocaine. Am J Ther. 2021 Mar-Apr 01; 28(2):e263-e265.

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