Osteogenesis

"Osteogenesis" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process of bone formation. Histogenesis of bone including ossification.

Descriptor ID	D010012
MeSH Number(s)	G07.345.500.325.377.625.100.729 G11.427.578.100.729
Concept/Terms	Osteogenesis Osteogenesis Bone Formation Ossification Ossifications Osteoclastogenesis Osteoclastogenesis Osteoclastogeneses Endochondral Ossification Endochondral Ossification Endochondral Ossifications Ossification, Endochondral Ossifications, Endochondral Physiologic Ossification Physiologic Ossification Ossification, Physiological Physiological Ossification Ossification, Physiologic

Below are MeSH descriptors whose meaning is more general than "Osteogenesis".

Biological Sciences [G]
Physiological Phenomena [G07]
Growth and Development [G07.345]
Morphogenesis [G07.345.500]
Embryonic and Fetal Development [G07.345.500.325]
Organogenesis [G07.345.500.325.377]
Musculoskeletal Development [G07.345.500.325.377.625]
Bone Development [G07.345.500.325.377.625.100]
Osteogenesis [G07.345.500.325.377.625.100.729]
Musculoskeletal and Neural Physiological Phenomena [G11]
Musculoskeletal Physiological Phenomena [G11.427]
Musculoskeletal Development [G11.427.578]
Bone Development [G11.427.578.100]
Osteogenesis [G11.427.578.100.729]

Below are MeSH descriptors whose meaning is related to "Osteogenesis".

Below are MeSH descriptors whose meaning is more specific than "Osteogenesis".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Osteogenesis" by people in this website by year, and whether "Osteogenesis" was a major or minor topic of these publications.

Bar chart showing 37 publications over 16 distinct years, with a maximum of 6 publications in 2003

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	2	3
2003	2	4	6
2004	0	1	1
2006	3	1	4
2007	0	2	2
2008	1	1	2
2009	1	1	2
2010	1	1	2
2011	1	0	1
2012	0	3	3
2013	1	0	1
2014	2	0	2
2016	1	0	1
2017	3	2	5
2019	0	1	1
2020	0	1	1

Below are the most recent publications written about "Osteogenesis" by people in Profiles.

Kushwaha P, Kim S, Foxa GE, Michalski MN, Williams BO, Tomlinson RE, Riddle RC. Frizzled-4 is required for normal bone acquisition despite compensation by Frizzled-8. J Cell Physiol. 2020 10; 235(10):6673-6683.

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Li Z, Meyers CA, Chang L, Lee S, Li Z, Tomlinson R, Hoke A, Clemens TL, James AW. Fracture repair requires TrkA signaling by skeletal sensory nerves. J Clin Invest. 2019 12 02; 129(12):5137-5150.

View in: PubMed
Goh BC, Singhal V, Herrera AJ, Tomlinson RE, Kim S, Faugere MC, Germain-Lee EL, Clemens TL, Lee SJ, DiGirolamo DJ. Activin receptor type 2A (ACVR2A) functions directly in osteoblasts as a negative regulator of bone mass. J Biol Chem. 2017 08 18; 292(33):13809-13822.

View in: PubMed
Ziegler SG, Ferreira CR, MacFarlane EG, Riddle RC, Tomlinson RE, Chew EY, Martin L, Ma CT, Sergienko E, Pinkerton AB, Millán JL, Gahl WA, Dietz HC. Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase. Sci Transl Med. 2017 06 07; 9(393).

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Tomlinson RE, Li Z, Li Z, Minichiello L, Riddle RC, Venkatesan A, Clemens TL. NGF-TrkA signaling in sensory nerves is required for skeletal adaptation to mechanical loads in mice. Proc Natl Acad Sci U S A. 2017 05 02; 114(18):E3632-E3641.

View in: PubMed
Han D, Rodriguez-Bravo V, Charytonowicz E, Demicco E, Domingo-Domenech J, Maki RG, Cordon-Cardo C. Targeting sarcoma tumor-initiating cells through differentiation therapy. Stem Cell Res. 2017 May; 21:117-123.

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Moorer MC, Hebert C, Tomlinson RE, Iyer SR, Chason M, Stains JP. Defective signaling, osteoblastogenesis and bone remodeling in a mouse model of connexin 43 C-terminal truncation. J Cell Sci. 2017 02 01; 130(3):531-540.

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Tomlinson RE, Li Z, Zhang Q, Goh BC, Li Z, Thorek DLJ, Rajbhandari L, Brushart TM, Minichiello L, Zhou F, Venkatesan A, Clemens TL. NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone. Cell Rep. 2016 09 06; 16(10):2723-2735.

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Tomlinson RE, Silva MJ. HIF-1a regulates bone formation after osteogenic mechanical loading. Bone. 2015 Apr; 73:98-104.

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Tomlinson RE, Schmieder AH, Quirk JD, Lanza GM, Silva MJ. Antagonizing the av ß3 integrin inhibits angiogenesis and impairs woven but not lamellar bone formation induced by mechanical loading. J Bone Miner Res. 2014 Sep; 29(9):1970-80.

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