"Parkinson Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Descriptor ID |
D010300
|
| MeSH Number(s) |
C10.228.140.079.862.500 C10.228.662.600.400 C10.574.812
|
| Concept/Terms |
Parkinson Disease- Parkinson Disease
- Idiopathic Parkinson's Disease
- Lewy Body Parkinson Disease
- Lewy Body Parkinson's Disease
- Primary Parkinsonism
- Parkinsonism, Primary
- Parkinson Disease, Idiopathic
- Parkinson's Disease
- Parkinson's Disease, Idiopathic
- Parkinson's Disease, Lewy Body
- Idiopathic Parkinson Disease
- Paralysis Agitans
|
Below are MeSH descriptors whose meaning is more general than "Parkinson Disease".
Below are MeSH descriptors whose meaning is more specific than "Parkinson Disease".
This graph shows the total number of publications written about "Parkinson Disease" by people in this website by year, and whether "Parkinson Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 4 | 0 | 4 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 5 | 0 | 5 |
| 2010 | 6 | 1 | 7 |
| 2011 | 1 | 0 | 1 |
| 2012 | 4 | 0 | 4 |
| 2013 | 4 | 0 | 4 |
| 2014 | 10 | 0 | 10 |
| 2015 | 7 | 0 | 7 |
| 2016 | 6 | 1 | 7 |
| 2017 | 9 | 0 | 9 |
| 2018 | 4 | 1 | 5 |
| 2019 | 5 | 1 | 6 |
| 2020 | 3 | 0 | 3 |
| 2021 | 6 | 0 | 6 |
| 2022 | 4 | 0 | 4 |
| 2023 | 7 | 0 | 7 |
| 2024 | 2 | 2 | 4 |
| 2025 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "Parkinson Disease" by people in Profiles.
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Wu C, Alizadeh M, Kramer MK, Kroen MB, Ziechmann R, Mohamed FB, Wu Q, Johnson CL. Deep Brain Stimulation Electrode Deviations are Associated With Brain Stiffness Interfaces Measured by Magnetic Resonance Elastography. Oper Neurosurg. 2025 Oct 01; 29(4):517-525.
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Hines K, Noecker AM, Frankemolle-Gilbert AM, Liang TW, Ratliff J, Heiry M, McIntyre CC, Wu C. Prospective Connectomic-Based Deep Brain Stimulation Programming for Parkinson's Disease. Mov Disord. 2024 12; 39(12):2249-2258.
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Hines K, Sharan I, Schaefer J, Fayed I, Atik A, Matias CM, Wu C. Microelectrode Recording During Deep Brain Stimulation Does Not Consistently Represent Lead Trajectory. Oper Neurosurg. 2025 01 01; 28(1):38-42.
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Cheslow L, Snook AE, Waldman SA. Biomarkers for Managing Neurodegenerative Diseases. Biomolecules. 2024 03 26; 14(4).
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Daniels RJ, Grenet D, Knight CA. Impaired performance of rapid grip in people with Parkinson's disease and motor segmentation. Hum Mov Sci. 2024 Jun; 95:103201.
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Bland MD, Holleran CL, Newman CA, Fahey M, Nordahl TJ, DeAngelis TR, Ellis TD, Reisman DS, Earhart GM, Lang CE. ICF classification of therapeutic goals for outpatient episodes of neurorehabilitation in post-stroke and Parkinson disease. Disabil Rehabil. 2024 10; 46(20):4772-4778.
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Isaacson SH, Kremens D, Torres-Yaghi Y, Stocchi F, Antonini A. Importance of time to ON versus wearing OFF in total daily OFF time experienced by patients with Parkinson's disease. Parkinsonism Relat Disord. 2023 09; 114:105495.
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Rocha SM, Kirkley KS, Chatterjee D, Aboellail TA, Smeyne RJ, Tjalkens RB. Microglia-specific knock-out of NF-?B/IKK2 increases the accumulation of misfolded a-synuclein through the inhibition of p62/sequestosome-1-dependent autophagy in the rotenone model of Parkinson's disease. Glia. 2023 09; 71(9):2154-2179.
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Chung JW, Bower AE, Malik I, Martello JP, Knight CA, Jeka JJ, Burciu RG. Imaging the lower limb network in Parkinson's disease. Neuroimage Clin. 2023; 38:103399.
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Vedaei F, Fayed I, Alizadeh M, Miller C, Zhang AB, Koa V, Khan S, Mohamed FB, Wu C. Effect of Enlarged Perivascular Spaces in Reliable Distinction of Prospective Targeting During Deep Brain Stimulation in Patients With Advanced Parkinson's Disease: A Study of Deterministic and Probabilistic Tractography. Neurosurgery. 2023 09 01; 93(3):691-698.