"Protein Denaturation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.
| Descriptor ID |
D011489
|
| MeSH Number(s) |
E05.793.500 G01.154.651.750.500 G02.111.688.750.500
|
| Concept/Terms |
Protein Denaturation- Protein Denaturation
- Denaturation, Protein
- Denaturations, Protein
- Protein Denaturations
|
Below are MeSH descriptors whose meaning is more general than "Protein Denaturation".
Below are MeSH descriptors whose meaning is more specific than "Protein Denaturation".
This graph shows the total number of publications written about "Protein Denaturation" by people in this website by year, and whether "Protein Denaturation" was a major or minor topic of these publications.
To see the data from this visualization as text,
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 5 | 5 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 4 | 4 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 2 | 2 |
| 2013 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Denaturation" by people in Profiles.
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Masuda I, Sakaguchi R, Liu C, Gamper H, Hou YM. The temperature sensitivity of a mutation in the essential tRNA modification enzyme tRNA methyltransferase D (TrmD). J Biol Chem. 2013 Oct 4; 288(40):28987-96.
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Top A, Roberts CJ, Kiick KL. Conformational and aggregation properties of a PEGylated alanine-rich polypeptide. Biomacromolecules. 2011 Jun 13; 12(6):2184-92.
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De Zoysa Ariyananda L, Antonopoulos C, Currier J, Colman RF. In vitro hybridization and separation of hybrids of human adenylosuccinate lyase from wild-type and disease-associated mutant enzymes. Biochemistry. 2011 Mar 1; 50(8):1336-46.
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O'Malley MA, Naranjo AN, Lazarova T, Robinson AS. Analysis of adenosine A2a receptor stability: effects of ligands and disulfide bonds. Biochemistry. 2010 Nov 2; 49(43):9181-9.
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Nayak AP, Blachere FM, Hettick JM, Lukomski S, Schmechel D, Beezhold DH. Characterization of recombinant terrelysin, a hemolysin of Aspergillus terreus. Mycopathologia. 2011 Jan; 171(1):23-34.
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Blais JD, Chin KT, Zito E, Zhang Y, Heldman N, Harding HP, Fass D, Thorpe C, Ron D. A small molecule inhibitor of endoplasmic reticulum oxidation 1 (ERO1) with selectively reversible thiol reactivity. J Biol Chem. 2010 Jul 2; 285(27):20993-1003.
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Bhardwaj A, Walker-Kopp N, Wilkens S, Cingolani G. Foldon-guided self-assembly of ultra-stable protein fibers. Protein Sci. 2008 Sep; 17(9):1475-85.
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Farmer RS, Top A, Argust LM, Liu S, Kiick KL. Evaluation of conformation and association behavior of multivalent alanine-rich polypeptides. Pharm Res. 2008 Mar; 25(3):700-8.
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Bhardwaj A, Olia AS, Walker-Kopp N, Cingolani G. Domain organization and polarity of tail needle GP26 in the portal vertex structure of bacteriophage P22. J Mol Biol. 2007 Aug 10; 371(2):374-87.
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Powers SL, Robinson CR, Robinson AS. Denaturation of an extremely stable hyperthermophilic protein occurs via a dimeric intermediate. Extremophiles. 2007 Jan; 11(1):179-89.