"Protein Denaturation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Disruption of the non-covalent bonds and/or disulfide bonds responsible for maintaining the three-dimensional shape and activity of the native protein.
| Descriptor ID |
D011489
|
| MeSH Number(s) |
E05.793.500 G01.154.651.750.500 G02.111.688.750.500
|
| Concept/Terms |
Protein Denaturation- Protein Denaturation
- Denaturation, Protein
- Denaturations, Protein
- Protein Denaturations
|
Below are MeSH descriptors whose meaning is more general than "Protein Denaturation".
Below are MeSH descriptors whose meaning is more specific than "Protein Denaturation".
This graph shows the total number of publications written about "Protein Denaturation" by people in this website by year, and whether "Protein Denaturation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 3 | 3 |
| 1997 | 0 | 2 | 2 |
| 1998 | 0 | 1 | 1 |
| 1999 | 1 | 0 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 2 | 2 |
| 2004 | 0 | 5 | 5 |
| 2005 | 1 | 1 | 2 |
| 2006 | 0 | 4 | 4 |
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 2 | 2 |
| 2010 | 0 | 3 | 3 |
| 2011 | 0 | 5 | 5 |
| 2013 | 0 | 2 | 2 |
| 2016 | 1 | 0 | 1 |
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Below are the most recent publications written about "Protein Denaturation" by people in Profiles.
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Calero-Rubio C, Paik B, Jia X, Kiick KL, Roberts CJ. Predicting unfolding thermodynamics and stable intermediates for alanine-rich helical peptides with the aid of coarse-grained molecular simulation. Biophys Chem. 2016 10; 217:8-19.
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Maurer RW, Hunter AK, Robinson AS, Roberts CJ. Aggregates of a-chymotrypsinogen anneal to access more stable states. Biotechnol Bioeng. 2014 Apr; 111(4):782-91.
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Masuda I, Sakaguchi R, Liu C, Gamper H, Hou YM. The temperature sensitivity of a mutation in the essential tRNA modification enzyme tRNA methyltransferase D (TrmD). J Biol Chem. 2013 Oct 04; 288(40):28987-96.
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Spacek LA, Lutwama F, Shihab HM, Summerton J, Kamya MR, Ronald A, Laeyendecker O, Quinn TC, Mayanja-Kizza H. Diagnostic accuracy of ultrasensitive heat-denatured HIV-1 p24 antigen in non-B subtypes in Kampala, Uganda. Int J STD AIDS. 2011 Jun; 22(6):310-4.
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Top A, Roberts CJ, Kiick KL. Conformational and aggregation properties of a PEGylated alanine-rich polypeptide. Biomacromolecules. 2011 Jun 13; 12(6):2184-92.
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Khare G, Gupta V, Nangpal P, Gupta RK, Sauter NK, Tyagi AK. Ferritin structure from Mycobacterium tuberculosis: comparative study with homologues identifies extended C-terminus involved in ferroxidase activity. PLoS One. 2011 Apr 08; 6(4):e18570.
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De Zoysa Ariyananda L, Antonopoulos C, Currier J, Colman RF. In vitro hybridization and separation of hybrids of human adenylosuccinate lyase from wild-type and disease-associated mutant enzymes. Biochemistry. 2011 Mar 01; 50(8):1336-46.
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Roberti A, Rizzolio F, Lucchetti C, de Leval L, Giordano A. Ubiquitin-mediated protein degradation and methylation-induced gene silencing cooperate in the inactivation of the INK4/ARF locus in Burkitt lymphoma cell lines. Cell Cycle. 2011 Jan 01; 10(1):127-34.
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O'Malley MA, Naranjo AN, Lazarova T, Robinson AS. Analysis of adenosine A2a receptor stability: effects of ligands and disulfide bonds. Biochemistry. 2010 Nov 02; 49(43):9181-9.
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Nayak AP, Blachere FM, Hettick JM, Lukomski S, Schmechel D, Beezhold DH. Characterization of recombinant terrelysin, a hemolysin of Aspergillus terreus. Mycopathologia. 2011 Jan; 171(1):23-34.