Receptors, Glucocorticoid
"Receptors, Glucocorticoid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.
| Descriptor ID |
D011965
|
| MeSH Number(s) |
D12.776.826.750.430
|
| Concept/Terms |
Receptors, Glucocorticoid- Receptors, Glucocorticoid
- Receptors, Glucocorticoids
- Glucocorticoids Receptors
- Glucocorticoid Receptors
- Glucocorticoid Receptor
- Receptor, Glucocorticoid
Receptors, Corticoid Type II- Receptors, Corticoid Type II
- Corticoid Type II Receptors
- Corticoid II Receptor
- Receptor, Corticoid II
- Receptors, Corticoid II
- Corticoid II Receptors
|
Below are MeSH descriptors whose meaning is more general than "Receptors, Glucocorticoid".
Below are MeSH descriptors whose meaning is more specific than "Receptors, Glucocorticoid".
This graph shows the total number of publications written about "Receptors, Glucocorticoid" by people in this website by year, and whether "Receptors, Glucocorticoid" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1993 | 3 | 0 | 3 |
| 1995 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 0 | 1 |
| 2022 | 1 | 1 | 2 |
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Below are the most recent publications written about "Receptors, Glucocorticoid" by people in Profiles.
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Amin M, Syed S, Wu R, Postolache TT, Gragnoli C. Familial Linkage and Association of the NR3C1 Gene with Type 2 Diabetes and Depression Comorbidity. Int J Mol Sci. 2022 Oct 08; 23(19).
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Ramos-Ram?rez P, Tliba O. Glucocorticoid Insensitivity in Asthma: The Unique Role for Airway Smooth Muscle Cells. Int J Mol Sci. 2022 Aug 11; 23(16).
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Holmes L, Shutman E, Chinaka C, Deepika K, Pelaez L, Dabney KW. Aberrant Epigenomic Modulation of Glucocorticoid Receptor Gene (NR3C1) in Early Life Stress and Major Depressive Disorder Correlation: Systematic Review and Quantitative Evidence Synthesis. Int J Environ Res Public Health. 2019 11 04; 16(21).
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Panettieri RA, Schaafsma D, Amrani Y, Koziol-White C, Ostrom R, Tliba O. Non-genomic Effects of Glucocorticoids: An Updated View. Trends Pharmacol Sci. 2019 01; 40(1):38-49.
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Linnstaedt SD, Riker KD, Rueckeis CA, Kutchko KM, Lackey L, McCarthy KR, Tsai YH, Parker JS, Kurz MC, Hendry PL, Lewandowski C, Datner E, Pearson C, O'Neil B, Domeier R, Kaushik S, Laederach A, McLean SA. A Functional riboSNitch in the 3' Untranslated Region of FKBP5 Alters MicroRNA-320a Binding Efficiency and Mediates Vulnerability to Chronic Post-Traumatic Pain. J Neurosci. 2018 09 26; 38(39):8407-8420.
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Cvijanovich NZ, Anas N, Allen GL, Thomas NJ, Bigham MT, Weiss SL, Fitzgerald J, Checchia PA, Meyer K, Quasney M, Gedeit R, Freishtat RJ, Nowak J, Raj SS, Gertz S, Grunwell JR, Opoka A, Wong HR. Glucocorticoid Receptor Polymorphisms and Outcomes in Pediatric Septic Shock. Pediatr Crit Care Med. 2017 Apr; 18(4):299-303.
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Stephenson ST, Brown LA, Helms MN, Qu H, Brown SD, Brown MR, Fitzpatrick AM. Cysteine oxidation impairs systemic glucocorticoid responsiveness in children with difficult-to-treat asthma. J Allergy Clin Immunol. 2015 Aug; 136(2):454-61.e9.
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Durham A, Adcock IM, Tliba O. Steroid resistance in severe asthma: current mechanisms and future treatment. Curr Pharm Des. 2011; 17(7):674-84.
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McEwen BS, Kalia M. The role of corticosteroids and stress in chronic pain conditions. Metabolism. 2010 Oct; 59 Suppl 1:S9-15.
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Wargon V, Fernandez SV, Goin M, Giulianelli S, Russo J, Lanari C. Hypermethylation of the progesterone receptor A in constitutive antiprogestin-resistant mouse mammary carcinomas. Breast Cancer Res Treat. 2011 Apr; 126(2):319-32.