Refractory Period, Electrophysiological
"Refractory Period, Electrophysiological" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The period of time following the triggering of an ACTION POTENTIAL when the CELL MEMBRANE has changed to an unexcitable state and is gradually restored to the resting (excitable) state. During the absolute refractory period no other stimulus can trigger a response. This is followed by the relative refractory period during which the cell gradually becomes more excitable and the stronger impulse that is required to illicit a response gradually lessens to that required during the resting state.
| Descriptor ID |
D012032
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| MeSH Number(s) |
G07.265.753.770 G07.265.760 G11.561.601.770 G11.561.785
|
| Concept/Terms |
Refractory Period, Electrophysiological- Refractory Period, Electrophysiological
- Electrophysiological Refractory Period
- Electrophysiological Refractory Periods
- Refractory Periods, Electrophysiological
Inhibition, Wedensky- Inhibition, Wedensky
- Neuromuscular Fade
- Fade, Neuromuscular
- Neuromuscular Transmission Fade
- Fade, Neuromuscular Transmission
- Transmission Fade, Neuromuscular
- Vvedenskii Inhibition
- Wedensky Inhibition
- Inhibition, Vvedenskii
- Tetanic Fade
- Fade, Tetanic
Refractory Period, Neurologic- Refractory Period, Neurologic
- Neurologic Refractory Periods
- Period, Neurologic Refractory
- Refractory Period, Neurological
- Neurological Refractory Period
- Neurological Refractory Periods
- Refractory Periods, Neurological
- Refractory Periods, Neurologic
- Neurologic Refractory Period
- Periods, Neurologic Refractory
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Below are MeSH descriptors whose meaning is more general than "Refractory Period, Electrophysiological".
Below are MeSH descriptors whose meaning is more specific than "Refractory Period, Electrophysiological".
This graph shows the total number of publications written about "Refractory Period, Electrophysiological" by people in this website by year, and whether "Refractory Period, Electrophysiological" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2017 | 0 | 1 | 1 |
| 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Refractory Period, Electrophysiological" by people in Profiles.
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Burashnikov A. Investigational Anti-Atrial Fibrillation Pharmacology and Mechanisms by Which Antiarrhythmics Terminate the Arrhythmia: Where Are We in 2020? J Cardiovasc Pharmacol. 2020 11; 76(5):492-505.
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Burashnikov A, Barajas-Martinez H, Hu D, Robinson VM, Grunnet M, Antzelevitch C. The Small Conductance Calcium-Activated Potassium Channel Inhibitors NS8593 and UCL1684 Prevent the Development of Atrial Fibrillation Through Atrial-Selective Inhibition of Sodium Channel Activity. J Cardiovasc Pharmacol. 2020 08; 76(2):164-172.
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Liu G, Xue X, Gao C, Huang J, Qi D, Zhang Y, Dong JZ, Ma CS, Yan GX. Synergistic Effect of Dofetilide and Mexiletine on Prevention of Atrial Fibrillation. J Am Heart Assoc. 2017 May 18; 6(5).
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Burashnikov A, Barajas-Martinez H, Hu D, Nof E, Blazek J, Antzelevitch C. Atrial-selective prolongation of refractory period with AVE0118 is due principally to inhibition of sodium channel activity. J Cardiovasc Pharmacol. 2012 Jun; 59(6):539-46.
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Burashnikov A, Pourrier M, Gibson JK, Lynch JJ, Antzelevitch C. Rate-dependent effects of vernakalant in the isolated non-remodeled canine left atria are primarily due to block of the sodium channel: comparison with ranolazine and dl-sotalol. Circ Arrhythm Electrophysiol. 2012 Apr; 5(2):400-8.
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Burashnikov A, Belardinelli L, Antzelevitch C. Atrial-selective sodium channel block strategy to suppress atrial fibrillation: ranolazine versus propafenone. J Pharmacol Exp Ther. 2012 Jan; 340(1):161-8.
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Sicouri S, Burashnikov A, Belardinelli L, Antzelevitch C. Synergistic electrophysiologic and antiarrhythmic effects of the combination of ranolazine and chronic amiodarone in canine atria. Circ Arrhythm Electrophysiol. 2010 Feb; 3(1):88-95.
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Lum JJ, Ho RT. Dynamic effects of exercise and different escape rhythms on the supernormal period of an accessory pathway. J Cardiovasc Electrophysiol. 2007 Jun; 18(6):672-5.