Synaptic Transmission

"Synaptic Transmission" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The communication from a NEURON to a target (neuron, muscle, or secretory cell) across a SYNAPSE. In chemical synaptic transmission, the presynaptic neuron releases a NEUROTRANSMITTER that diffuses across the synaptic cleft and binds to specific synaptic receptors, activating them. The activated receptors modulate specific ion channels and/or second-messenger systems in the postsynaptic cell. In electrical synaptic transmission, electrical signals are communicated as an ionic current flow across ELECTRICAL SYNAPSES.

Descriptor ID	D009435
MeSH Number(s)	G02.111.820.850 G04.835.850 G07.265.880 G11.561.830
Concept/Terms	Synaptic Transmission Synaptic Transmission Neural Transmission Neurotransmission Transmission, Neural Transmission, Synaptic

Below are MeSH descriptors whose meaning is more general than "Synaptic Transmission".

Biological Sciences [G]
Chemical Phenomena [G02]
Biochemical Phenomena [G02.111]
Signal Transduction [G02.111.820]
Synaptic Transmission [G02.111.820.850]
Cell Physiological Phenomena [G04]
Signal Transduction [G04.835]
Synaptic Transmission [G04.835.850]
Physiological Phenomena [G07]
Electrophysiological Phenomena [G07.265]
Synaptic Transmission [G07.265.880]
Musculoskeletal and Neural Physiological Phenomena [G11]
Nervous System Physiological Phenomena [G11.561]
Synaptic Transmission [G11.561.830]

Below are MeSH descriptors whose meaning is related to "Synaptic Transmission".

Below are MeSH descriptors whose meaning is more specific than "Synaptic Transmission".

Synaptic Transmission
Postsynaptic Potential Summation

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Synaptic Transmission" by people in this website by year, and whether "Synaptic Transmission" was a major or minor topic of these publications.

Bar chart showing 30 publications over 17 distinct years, with a maximum of 4 publications in 2010 and 2014

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1997	0	2	2
1999	0	1	1
2000	0	1	1
2002	0	3	3
2003	0	1	1
2006	1	1	2
2008	0	2	2
2010	0	4	4
2012	1	2	3
2013	0	1	1
2014	2	2	4
2015	1	0	1
2017	1	0	1
2018	0	1	1
2020	0	1	1
2021	0	1	1
2023	0	1	1

Below are the most recent publications written about "Synaptic Transmission" by people in Profiles.

Parisi MJ, Aimino MA, Mosca TJ. A conditional strategy for cell-type-specific labeling of endogenous excitatory synapses in Drosophila. Cell Rep Methods. 2023 05 22; 3(5):100477.

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Krishnamurthy K, Trotti D, Pasinelli P, Jensen B. Real-Time Fluorescent Measurement of Synaptic Functions in Models of Amyotrophic Lateral Sclerosis. J Vis Exp. 2021 07 16; (173).

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Showell SS, Martinez Y, Gondolfo S, Boppana S, Lawal HO. Overexpression of the vesicular acetylcholine transporter disrupts cognitive performance and causes age-dependent locomotion decline in Drosophila. Mol Cell Neurosci. 2020 06; 105:103483.

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Henderson NT, Dalva MB. EphBs and ephrin-Bs: Trans-synaptic organizers of synapse development and function. Mol Cell Neurosci. 2018 09; 91:108-121.

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Wu M, White HV, Boehm BA, Meriney CJ, Kerrigan K, Frasso M, Liang M, Gotway EM, Wilcox MR, Johnson JW, Wipf P, Meriney SD. New Cav2 calcium channel gating modifiers with agonist activity and therapeutic potential to treat neuromuscular disease. Neuropharmacology. 2018 03 15; 131:176-189.

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Khambhati AN, Davis KA, Oommen BS, Chen SH, Lucas TH, Litt B, Bassett DS. Dynamic Network Drivers of Seizure Generation, Propagation and Termination in Human Neocortical Epilepsy. PLoS Comput Biol. 2015 Dec; 11(12):e1004608.

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Yao C, Vanderpool KG, Delfiner M, Eddy V, Lucaci AG, Soto-Riveros C, Yasumura T, Rash JE, Pereda AE. Electrical synaptic transmission in developing zebrafish: properties and molecular composition of gap junctions at a central auditory synapse. J Neurophysiol. 2014 Nov 01; 112(9):2102-13.

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Chun S, Westmoreland JJ, Bayazitov IT, Eddins D, Pani AK, Smeyne RJ, Yu J, Blundon JA, Zakharenko SS. Specific disruption of thalamic inputs to the auditory cortex in schizophrenia models. Science. 2014 Jun 06; 344(6188):1178-82.

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McKimm E, Corkill B, Goldowitz D, Albritton LM, Homayouni R, Blaha CD, Mittleman G. Glutamate dysfunction associated with developmental cerebellar damage: relevance to autism spectrum disorders. Cerebellum. 2014 Jun; 13(3):346-53.

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Park J, Brureau A, Kernan K, Starks A, Gulati S, Ogunnaike B, Schwaber J, Vadigepalli R. Inputs drive cell phenotype variability. Genome Res. 2014 Jun; 24(6):930-41.

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