RNA, Messenger

"RNA, Messenger" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Descriptor ID	D012333
MeSH Number(s)	D13.444.735.544
Concept/Terms	RNA, Messenger RNA, Messenger mRNA Messenger RNA RNA, Polyadenylated RNA, Polyadenylated Polyadenylated RNA Poly(A) RNA Poly(A)+ RNA Poly(A) Tail Poly(A) Tail mRNA, Non-Polyadenylated mRNA, Non-Polyadenylated mRNA, Non Polyadenylated Non-Polyadenylated mRNA Non Polyadenylated mRNA mRNA, Polyadenylated mRNA, Polyadenylated RNA, Messenger, Polyadenylated Messenger RNA, Polyadenylated Polyadenylated Messenger RNA RNA, Polyadenylated Messenger Polyadenylated mRNA Poly(A)+ mRNA

Below are MeSH descriptors whose meaning is more general than "RNA, Messenger".

Chemicals and Drugs [D]
Nucleic Acids, Nucleotides, and Nucleosides [D13]
Nucleic Acids [D13.444]
RNA [D13.444.735]
RNA, Messenger [D13.444.735.544]

Below are MeSH descriptors whose meaning is related to "RNA, Messenger".

Below are MeSH descriptors whose meaning is more specific than "RNA, Messenger".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "RNA, Messenger" by people in this website by year, and whether "RNA, Messenger" was a major or minor topic of these publications.

Bar chart showing 733 publications over 31 distinct years, with a maximum of 62 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	2	1	3
1996	1	7	8
1997	0	5	5
1998	0	7	7
1999	0	11	11
2000	3	7	10
2001	1	14	15
2002	5	56	61
2003	8	53	61
2004	9	39	48
2005	5	57	62
2006	5	53	58
2007	6	41	47
2008	6	46	52
2009	2	42	44
2010	5	40	45
2011	8	34	42
2012	4	23	27
2013	4	10	14
2014	6	12	18
2015	4	17	21
2016	4	8	12
2017	5	9	14
2018	1	4	5
2019	2	8	10
2020	3	5	8
2021	5	6	11
2022	1	9	10
2023	0	2	2
2024	1	0	1
2025	0	1	1

Below are the most recent publications written about "RNA, Messenger" by people in Profiles.

Ibrahim F, Mourelatos Z. Defining the True Native Ends of RNAs at Single-Molecule Level with TERA-Seq. Methods Mol Biol. 2025; 2863:359-372.

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Vukovic I, Barnada SM, Ruffin JW, Karlin J, Lokareddy RK, Cingolani G, McMahon SB. Non-redundant roles for the human mRNA decapping cofactor paralogs DCP1a and DCP1b. Life Sci Alliance. 2024 Nov; 7(11).

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Qin J, Jeon JH, Xu J, Langston LK, Marasini R, Mou S, Montoya B, Melo-Silva CR, Jeon HJ, Zhu T, Sigal LJ, Xu R, Zhu H. Design and preclinical evaluation of a universal SARS-CoV-2 mRNA vaccine. Front Immunol. 2023; 14:1126392.

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Beyoglu D, Schwalm S, Semmo N, Huwiler A, Idle JR. Hepatitis C Virus Infection Upregulates Plasma Phosphosphingolipids and Endocannabinoids and Downregulates Lysophosphoinositols. Int J Mol Sci. 2023 01 11; 24(2).

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Manne BK, Campbell RA, Bhatlekar S, Ajanel A, Denorme F, Portier I, Middleton EA, Tolley ND, Kosaka Y, Montenont E, Guo L, Rowley JW, Bray PF, Jacob S, Fukanaga R, Proud C, Weyrich AS, Rondina MT. MAPK-interacting kinase 1 regulates platelet production, activation, and thrombosis. Blood. 2022 12 08; 140(23):2477-2489.

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Schumacher D, Curaj A, Staudt M, Simsekyilmaz S, Kanzler I, Boor P, Klinkhammer BM, Li X, Bucur O, Kaabi A, Xu Y, Zheng H, Nilcham P, Schuh A, Rusu M, Liehn EA. Endogenous Modulation of Extracellular Matrix Collagen during Scar Formation after Myocardial Infarction. Int J Mol Sci. 2022 Nov 23; 23(23).

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Kuttiyatveetil JRA, Soufari H, Dasovich M, Uribe IR, Mirhasan M, Cheng SJ, Leung AKL, Pascal JM. Crystal structures and functional analysis of the ZnF5-WWE1-WWE2 region of PARP13/ZAP define a distinctive mode of engaging poly(ADP-ribose). Cell Rep. 2022 10 25; 41(4):111529.

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Britto C, Mohorianu I, Yeung T, Cheung E, Novak T, Hall MW, Mourani PM, Weiss SL, Thomas NJ, Markovitz B, Randolph AG, Moffitt KL. Host Respiratory Transcriptome Signature Associated with Poor Outcome in Children with Influenza-Staphylococcus aureus Pneumonia. J Infect Dis. 2022 09 28; 226(7):1286-1294.

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Korzun T, Moses AS, Kim J, Patel S, Schumann C, Levasseur PR, Diba P, Olson B, Rebola KGO, Norgard M, Park Y, Demessie AA, Eygeris Y, Grigoriev V, Sundaram S, Pejovic T, Brody JR, Taratula OR, Zhu X, Sahay G, Marks DL, Taratula O. Nanoparticle-Based Follistatin Messenger RNA Therapy for Reprogramming Metastatic Ovarian Cancer and Ameliorating Cancer-Associated Cachexia. Small. 2022 11; 18(44):e2204436.

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Kumar S, Mulchandani V, Das Sarma J. Methanolic neem (Azadirachta indica) stem bark extract induces cell cycle arrest, apoptosis and inhibits the migration of cervical cancer cells in vitro. BMC Complement Med Ther. 2022 Sep 10; 22(1):239.

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