"Sarcomeres" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The repeating contractile units of the MYOFIBRIL, delimited by Z bands along its length.
| Descriptor ID |
D012518
|
| MeSH Number(s) |
A10.690.552.875.700 A11.284.430.214.190.875.820 A11.620.249.850.700 A11.620.500.500.700
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Sarcomeres".
Below are MeSH descriptors whose meaning is more specific than "Sarcomeres".
This graph shows the total number of publications written about "Sarcomeres" by people in this website by year, and whether "Sarcomeres" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2020 | 0 | 2 | 2 |
| 2021 | 1 | 2 | 3 |
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click here.
Below are the most recent publications written about "Sarcomeres" by people in Profiles.
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Barrick SK, Greenberg L, Greenberg MJ. A troponin T variant linked with pediatric dilated cardiomyopathy reduces the coupling of thin filament activation to myosin and calcium binding. Mol Biol Cell. 2021 08 19; 32(18):1677-1689.
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Clippinger SR, Cloonan PE, Wang W, Greenberg L, Stump WT, Angsutararux P, Nerbonne JM, Greenberg MJ. Mechanical dysfunction of the sarcomere induced by a pathogenic mutation in troponin T drives cellular adaptation. J Gen Physiol. 2021 05 03; 153(5).
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Greenberg MJ, Tardiff JC. Complexity in genetic cardiomyopathies and new approaches for mechanism-based precision medicine. J Gen Physiol. 2021 03 01; 153(3).
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Cassandrini D, Merlini L, Pilla F, Cenni V, Santi S, Faldini C, Santorelli FM, Sabatelli P. Protein aggregates and autophagy involvement in a family with a mutation in Z-band alternatively spliced PDZ-motif protein. Neuromuscul Disord. 2021 01; 31(1):44-51.
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Ezekian JE, Clippinger SR, Garcia JM, Yang Q, Denfield S, Jeewa A, Dreyer WJ, Zou W, Fan Y, Allen HD, Kim JJ, Greenberg MJ, Landstrom AP. Variant R94C in TNNT2-Encoded Troponin T Predisposes to Pediatric Restrictive Cardiomyopathy and Sudden Death Through Impaired Thin Filament Relaxation Resulting in Myocardial Diastolic Dysfunction. J Am Heart Assoc. 2020 03 03; 9(5):e015111.
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Nan C, Dube S, Matoq A, Mikesell L, Abbott L, Alshiekh-Nasany R, Chionuma H, Huang X, Poiesz BJ, Dube DK. Expression of sarcomeric tropomyosin in striated muscles in axolotl treated with shz-1, a small cardiogenic molecule. Cardiovasc Toxicol. 2015 Jan; 15(1):29-40.
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Ward SR, Sarver JJ, Eng CM, Kwan A, W?rgler-Hauri CC, Perry SM, Williams GR, Soslowsky LJ, Lieber RL. Plasticity of muscle architecture after supraspinatus tears. J Orthop Sports Phys Ther. 2010 Nov; 40(11):729-35.
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Yang Z, Yamazaki M, Shen QW, Swartz DR. Differences between cardiac and skeletal troponin interaction with the thin filament probed by troponin exchange in skeletal myofibrils. Biophys J. 2009 Jul 08; 97(1):183-94.
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Davis JP, Norman C, Kobayashi T, Solaro RJ, Swartz DR, Tikunova SB. Effects of thin and thick filament proteins on calcium binding and exchange with cardiac troponin C. Biophys J. 2007 May 01; 92(9):3195-206.
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Fukuda N, O-Uchi J, Sasaki D, Kajiwara H, Ishiwata S, Kurihara S. Acidosis or inorganic phosphate enhances the length dependence of tension in rat skinned cardiac muscle. J Physiol. 2001 Oct 1; 536(Pt 1):153-60.