"Spectrin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A high molecular weight (220-250 kDa) water-soluble protein which can be extracted from erythrocyte ghosts in low ionic strength buffers. The protein contains no lipids or carbohydrates, is the predominant species of peripheral erythrocyte membrane proteins, and exists as a fibrous coating on the inner, cytoplasmic surface of the membrane.
| Descriptor ID |
D013049
|
| MeSH Number(s) |
D12.776.220.980 D12.776.543.850
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Spectrin".
Below are MeSH descriptors whose meaning is more specific than "Spectrin".
This graph shows the total number of publications written about "Spectrin" by people in this website by year, and whether "Spectrin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2006 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Spectrin" by people in Profiles.
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Risinger M, Christakopoulos GE, Schultz CL, McGann PT, Zhang W, Kalfa TA. Hereditary elliptocytosis-associated alpha-spectrin mutation p.L155dup as a modifier of sickle cell disease severity. Pediatr Blood Cancer. 2019 02; 66(2):e27531.
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Wolgast LR, Cannizzarro LA, Ramesh KH, Xue X, Wang D, Bhattacharyya PK, Gong JZ, McMahon C, Albanese JM, Sunkara JL, Ratech H. Spectrin isoforms: differential expression in normal hematopoiesis and alterations in neoplastic bone marrow disorders. Am J Clin Pathol. 2011 Aug; 136(2):300-8.
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Bauer P, Sch?ls L, Riess O. Spectrin mutations in spinocerebellar ataxia (SCA). Bioessays. 2006 Aug; 28(8):785-7.
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Saatman KE, Abai B, Grosvenor A, Vorwerk CK, Smith DH, Meaney DF. Traumatic axonal injury results in biphasic calpain activation and retrograde transport impairment in mice. J Cereb Blood Flow Metab. 2003 Jan; 23(1):34-42.