"Synapses" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized junctions at which a neuron communicates with a target cell. At classical synapses, a neuron's presynaptic terminal releases a chemical transmitter stored in synaptic vesicles which diffuses across a narrow synaptic cleft and activates receptors on the postsynaptic membrane of the target cell. The target may be a dendrite, cell body, or axon of another neuron, or a specialized region of a muscle or secretory cell. Neurons may also communicate via direct electrical coupling with ELECTRICAL SYNAPSES. Several other non-synaptic chemical or electric signal transmitting processes occur via extracellular mediated interactions.
| Descriptor ID |
D013569
|
| MeSH Number(s) |
A08.850 A11.284.149.165.420.780
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Synapses".
Below are MeSH descriptors whose meaning is more specific than "Synapses".
This graph shows the total number of publications written about "Synapses" by people in this website by year, and whether "Synapses" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 1 | 1 | 2 |
| 2004 | 1 | 1 | 2 |
| 2005 | 2 | 1 | 3 |
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2008 | 4 | 0 | 4 |
| 2009 | 4 | 3 | 7 |
| 2010 | 7 | 4 | 11 |
| 2011 | 3 | 2 | 5 |
| 2012 | 5 | 0 | 5 |
| 2013 | 4 | 0 | 4 |
| 2014 | 2 | 0 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 1 | 2 |
| 2019 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 0 | 1 | 1 |
| 2022 | 2 | 2 | 4 |
| 2023 | 2 | 1 | 3 |
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Below are the most recent publications written about "Synapses" by people in Profiles.
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Dalva MB. Brain cancer thrives by hijacking mechanisms to boost synapse strength. Nature. 2023 Nov; 623(7986):260-262.
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Ogunmowo TH, Jing H, Raychaudhuri S, Kusick GF, Imoto Y, Li S, Itoh K, Ma Y, Jafri H, Dalva MB, Chapman ER, Ha T, Watanabe S, Liu J. Membrane compression by synaptic vesicle exocytosis triggers ultrafast endocytosis. Nat Commun. 2023 May 20; 14(1):2888.
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Parisi MJ, Aimino MA, Mosca TJ. A conditional strategy for cell-type-specific labeling of endogenous excitatory synapses in Drosophila. Cell Rep Methods. 2023 May 22; 3(5):100477.
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Aimino MA, DePew AT, Restrepo L, Mosca TJ. Synaptic Development in Diverse Olfactory Neuron Classes Uses Distinct Temporal and Activity-Related Programs. J Neurosci. 2023 Jan 04; 43(1):28-55.
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Washburn HR, Chander P, Srikanth KD, Dalva MB. Transsynaptic Signaling of Ephs in Synaptic Development, Plasticity, and Disease. Neuroscience. 2023 Jan 01; 508:137-152.
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Anikeeva N, Steblyanko M, Kuri-Cervantes L, Buggert M, Betts MR, Sykulev Y. The immune synapses reveal aberrant functions of CD8 T cells during chronic HIV infection. Nat Commun. 2022 10 28; 13(1):6436.
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Hruska M, Cain RE, Dalva MB. Nanoscale rules governing the organization of glutamate receptors in spine synapses are subunit specific. Nat Commun. 2022 02 17; 13(1):920.
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Miller KD, Matullo C, Williams R, Jones CB, Rall GF. Murine BST2/tetherin promotes measles virus infection of neurons. Virology. 2021 11; 563:38-43.
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Washburn HR, Xia NL, Zhou W, Mao YT, Dalva MB. Positive surface charge of GluN1 N-terminus mediates the direct interaction with EphB2 and NMDAR mobility. Nat Commun. 2020 Jan 29; 11(1):570.
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Wright-Jin EC, Gutmann DH. Microglia as Dynamic Cellular Mediators of Brain Function. Trends Mol Med. 2019 11; 25(11):967-979.