"Chagas Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Descriptor ID |
D014355
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| MeSH Number(s) |
C03.752.300.900.200
|
| Concept/Terms |
Chagas Disease- Chagas Disease
- Chagas' Disease
- American Trypanosomiasis
- Trypanosomiasis, American
- Trypanosomiasis, South American
- South American Trypanosomiasis
- Trypanosoma cruzi Infection
- Infection, Trypanosoma cruzi
- Infections, Trypanosoma cruzi
- Trypanosoma cruzi Infections
|
Below are MeSH descriptors whose meaning is more general than "Chagas Disease".
Below are MeSH descriptors whose meaning is more specific than "Chagas Disease".
This graph shows the total number of publications written about "Chagas Disease" by people in this website by year, and whether "Chagas Disease" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Chagas Disease" by people in Profiles.
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Cafferata ML, Toscani MA, Althabe F, Beliz?n JM, Bergel E, Berrueta M, Capparelli EV, Ciganda ?, Danesi E, Dumonteil E, Gibbons L, Gulayin PE, Herrera C, Momper JD, Rossi S, Shaffer JG, Schijman AG, Sosa-Estani S, Stella CB, Klein K, Buekens P. Short-course Benznidazole treatment to reduce Trypanosoma cruzi parasitic load in women of reproductive age (BETTY): a non-inferiority randomized controlled trial study protocol. Reprod Health. 2020 Aug 24; 17(1):128.
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Bouzahzah B, Yurchenko V, Nagajyothi F, Hulit J, Sadofsky M, Braunstein VL, Mukherjee S, Weiss H, Machado FS, Pestell RG, Lisanti MP, Tanowitz HB, Albanese C. Regulation of host cell cyclin D1 by Trypanosoma cruzi in myoblasts. Cell Cycle. 2008 Feb 15; 7(4):500-3.
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Bouzahzah B, Nagajyothi F, Desruisseaux MS, Krishnamachary M, Factor SM, Cohen AW, Lisanti MP, Petkova SB, Pestell RG, Wittner M, Mukherjee S, Weiss LM, Jelicks LA, Albanese C, Tanowitz HB. Cell cycle regulatory proteins in the liver in murine Trypanosoma cruzi infection. Cell Cycle. 2006 Oct; 5(20):2396-400.
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Hassan GS, Mukherjee S, Nagajyothi F, Weiss LM, Petkova SB, de Almeida CJ, Huang H, Desruisseaux MS, Bouzahzah B, Pestell RG, Albanese C, Christ GJ, Lisanti MP, Tanowitz HB. Trypanosoma cruzi infection induces proliferation of vascular smooth muscle cells. Infect Immun. 2006 Jan; 74(1):152-9.
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Petkova SB, Huang H, Factor SM, Pestell RG, Bouzahzah B, Jelicks LA, Weiss LM, Douglas SA, Wittner M, Tanowitz HB. The role of endothelin in the pathogenesis of Chagas' disease. Int J Parasitol. 2001 May 1; 31(5-6):499-511.
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Huang H, Petkova SB, Pestell RG, Bouzahzah B, Chan J, Magazine H, Weiss LM, Christ GJ, Lisanti MP, Douglas SA, Shtutin V, Halonen SK, Wittner M, Tanowitz HB. Trypanosoma cruzi infection (Chagas' disease) of mice causes activation of the mitogen-activated protein kinase cascade and expression of endothelin-1 in the myocardium. J Cardiovasc Pharmacol. 2000 Nov; 36(5 Suppl 1):S148-50.