"NADPH Oxidase 4" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is strongly expressed in the kidney. It forms a complex with CYBA-P22PHOX and produces intracellular SUPEROXIDES that may regulate cellular signaling in APOPTOSIS; BONE RESORPTION; and NF-KAPPA B activation.
| Descriptor ID |
D000074663
|
| MeSH Number(s) |
D08.811.682.608.575.937 D12.776.331.894.937 D12.776.543.653.937
|
| Concept/Terms |
NADPH Oxidase 4- NADPH Oxidase 4
- Oxidase 4, NADPH
- Renal NAD(P)H Oxidase
- Nox4 Protein
- Renox NAD(P)H Oxidase
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 4".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 4".
This graph shows the total number of publications written about "NADPH Oxidase 4" by people in this website by year, and whether "NADPH Oxidase 4" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "NADPH Oxidase 4" by people in Profiles.
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Cowley AW, Yang C, Zheleznova NN, Staruschenko A, Kurth T, Rein L, Kumar V, Sadovnikov K, Dayton A, Hoffman M, Ryan RP, Skelton MM, Salehpour F, Ranji M, Geurts A. Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. Hypertension. 2016 Feb; 67(2):440-50.
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Kern G, Mair SM, Noppert SJ, Jennings P, Schramek H, Rudnicki M, Mueller GA, Mayer G, Koppelstaetter C. Tacrolimus increases Nox4 expression in human renal fibroblasts and induces fibrosis-related genes by aberrant TGF-beta receptor signalling. PLoS One. 2014; 9(5):e96377.
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Hagler MA, Hadley TM, Zhang H, Mehra K, Roos CM, Schaff HV, Suri RM, Miller JD. TGF-? signalling and reactive oxygen species drive fibrosis and matrix remodelling in myxomatous mitral valves. Cardiovasc Res. 2013 Jul 01; 99(1):175-84.
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Babelova A, Avaniadi D, Jung O, Fork C, Beckmann J, Kosowski J, Weissmann N, Anilkumar N, Shah AM, Schaefer L, Schr?der K, Brandes RP. Role of Nox4 in murine models of kidney disease. Free Radic Biol Med. 2012 Aug 15; 53(4):842-53.