"NADPH Oxidase 2" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An NADPH oxidase that is expressed by PHAGOCYTES where it transfers electrons across the plasma membrane from cytosolic NADPH to molecular oxygen on the exterior. It regulates proton (H+) flux into resting phagocytes to control intracellular pH. Mutations in the CYBB gene are associated with X-LINKED CHRONIC GRANULOMATOUS DISEASE.
| Descriptor ID |
D000074662
|
| MeSH Number(s) |
D08.811.682.608.575.875 D12.776.331.894.875 D12.776.543.653.875
|
| Concept/Terms |
NADPH Oxidase 2- NADPH Oxidase 2
- Oxidase 2, NADPH
- Chronic Granulomatous Disease Protein
- GP91-PHOX Protein
- GP91 PHOX Protein
- CYBB Protein
- Cytochrome B-245 Beta Chain
- Cytochrome B 245 Beta Chain
- NOX2 Protein
|
Below are MeSH descriptors whose meaning is more general than "NADPH Oxidase 2".
Below are MeSH descriptors whose meaning is more specific than "NADPH Oxidase 2".
This graph shows the total number of publications written about "NADPH Oxidase 2" by people in this website by year, and whether "NADPH Oxidase 2" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2015 | 0 | 3 | 3 |
| 2017 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "NADPH Oxidase 2" by people in Profiles.
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Guers JJ, Kasecky-Lardner L, Farquhar WB, Edwards DG, Lennon SL. Voluntary wheel running prevents salt-induced endothelial dysfunction: role of oxidative stress. J Appl Physiol (1985). 2019 02 01; 126(2):502-510.
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Bhardwaj V, Gokulan RC, Horvat A, Yermalitskaya L, Korolkova O, Washington KM, El-Rifai W, Dikalov SI, Zaika AI. Activation of NADPH oxidases leads to DNA damage in esophageal cells. Sci Rep. 2017 08 30; 7(1):9956.
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Hsieh LT, Frey H, Nastase MV, Tredup C, Hoffmann A, Poluzzi C, Zeng-Brouwers J, Manon-Jensen T, Schr?der K, Brandes RP, Iozzo RV, Schaefer L. Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1? synthesis. Matrix Biol. 2016 Jan; 49:61-81.
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Cheng G, Lanza-Jacoby S. Metformin decreases growth of pancreatic cancer cells by decreasing reactive oxygen species: Role of NOX4. Biochem Biophys Res Commun. 2015 Sep 11; 465(1):41-6.
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Huang YF, Lo PC, Yen CL, Nigrovic PA, Chao WC, Wang WZ, Hsu GC, Tsai YS, Shieh CC. Redox Regulation of Pro-IL-1? Processing May Contribute to the Increased Severity of Serum-Induced Arthritis in NOX2-Deficient Mice. Antioxid Redox Signal. 2015 Oct 20; 23(12):973-84.
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Hagler MA, Hadley TM, Zhang H, Mehra K, Roos CM, Schaff HV, Suri RM, Miller JD. TGF-? signalling and reactive oxygen species drive fibrosis and matrix remodelling in myxomatous mitral valves. Cardiovasc Res. 2013 Jul 01; 99(1):175-84.
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Mantegazza AR, Savina A, Vermeulen M, P?rez L, Geffner J, Hermine O, Rosenzweig SD, Faure F, Amigorena S. NADPH oxidase controls phagosomal pH and antigen cross-presentation in human dendritic cells. Blood. 2008 Dec 01; 112(12):4712-22.
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Li R, Wang WQ, Zhang H, Yang X, Fan Q, Christopher TA, Lopez BL, Tao L, Goldstein BJ, Gao F, Ma XL. Adiponectin improves endothelial function in hyperlipidemic rats by reducing oxidative/nitrative stress and differential regulation of eNOS/iNOS activity. Am J Physiol Endocrinol Metab. 2007 Dec; 293(6):E1703-8.
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Tao L, Gao E, Jiao X, Yuan Y, Li S, Christopher TA, Lopez BL, Koch W, Chan L, Goldstein BJ, Ma XL. Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress. Circulation. 2007 Mar 20; 115(11):1408-16.