"Patched Receptors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A family of 12-pass transmembrane proteins originally identified in Drosophila that are receptors for HEDGEHOG PROTEINS. They have important roles in regulating CELL PROLIFERATION; CELL DIFFERENTIAION; and BODY PATTERNING and may also function as TUMOR SUPPRESSOR PROTEINS.
| Descriptor ID |
D000072079
|
| MeSH Number(s) |
D12.776.543.750.058 D12.776.624.776.633
|
| Concept/Terms |
Patched Receptors- Patched Receptors
- Receptors, Patched
- Patched Sonic Hedgehog Receptors
- Patched Receptor
- Receptor, Patched
- Patched Protein
|
Below are MeSH descriptors whose meaning is more general than "Patched Receptors".
Below are MeSH descriptors whose meaning is more specific than "Patched Receptors".
This graph shows the total number of publications written about "Patched Receptors" by people in this website by year, and whether "Patched Receptors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2011 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
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Below are the most recent publications written about "Patched Receptors" by people in Profiles.
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Sims-Mourtada J, Yang D, Tworowska I, Larson R, Smith D, Tsao N, Opdenaker L, Mourtada F, Woodward W. Detection of canonical hedgehog signaling in breast cancer by 131-iodine-labeled derivatives of the sonic hedgehog protein. J Biomed Biotechnol. 2012; 2012:639562.
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Li X, Howard TD, Moore WC, Ampleford EJ, Li H, Busse WW, Calhoun WJ, Castro M, Chung KF, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Peters SP, Hawkins GA, Bleecker ER, Meyers DA. Importance of hedgehog interacting protein and other lung function genes in asthma. J Allergy Clin Immunol. 2011 Jun; 127(6):1457-65.
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Brellier F, Marionnet C, Chevallier-Lagente O, Toftgard R, Mauviel A, Sarasin A, Magnaldo T. Ultraviolet irradiation represses PATCHED gene transcription in human epidermal keratinocytes through an activator protein-1-dependent process. Cancer Res. 2004 Apr 15; 64(8):2699-704.