"Synoviocytes" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cells on the luminal surface of the SYNOVIAL MEMBRANE. Type A synoviocytes are MACROPHAGES responsible for waste removal from the joint cavity. Fibroblast-like type B synoviocytes are involved in production of joint matrix constituents (e.g., HYALURONAN; COLLAGEN; and FIBRONECTIN).
| Descriptor ID |
D000070918
|
| MeSH Number(s) |
A11.329.835
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Synoviocytes".
Below are MeSH descriptors whose meaning is more specific than "Synoviocytes".
This graph shows the total number of publications written about "Synoviocytes" by people in this website by year, and whether "Synoviocytes" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2017 | 1 | 0 | 1 |
| 2018 | 2 | 0 | 2 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 0 | 1 |
| 2022 | 1 | 0 | 1 |
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Below are the most recent publications written about "Synoviocytes" by people in Profiles.
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Simonds MM, Sullivan KE, Brescia AC. Single-cell analysis reveals heterogeneity of juvenile idiopathic arthritis fibroblast-like synoviocytes with implications for disease subtype. Arthritis Res Ther. 2022 09 27; 24(1):225.
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Simonds MM, Schlefman AR, McCahan SM, Sullivan KE, Rose CD, Brescia AMC. The culture microenvironment of juvenile idiopathic arthritis synovial fibroblasts is favorable for endochondral bone formation through BMP4 and repressed by chondrocytes. Pediatr Rheumatol Online J. 2021 May 12; 19(1):72.
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Simonds MM, Schlefman AR, McCahan SM, Sullivan KE, Rose CD, Brescia AC. Juvenile idiopathic arthritis fibroblast-like synoviocytes influence chondrocytes to alter BMP antagonist expression demonstrating an interaction between the two prominent cell types involved in endochondral bone formation. Pediatr Rheumatol Online J. 2020 Nov 16; 18(1):89.
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Tang MW, Malvar Fernández B, Newsom SP, van Buul JD, Radstake TRDJ, Baeten DL, Tak PP, Reedquist KA, García S. Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes. Rheumatology (Oxford). 2018 05 01; 57(5):909-920.
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Brescia AC, Simonds MM, McCahan SM, Sullivan KE, Rose CD. Prior to extension, Transcriptomes of fibroblast-like Synoviocytes from extended and Polyarticular juvenile idiopathic arthritis are indistinguishable. Pediatr Rheumatol Online J. 2018 Jan 08; 16(1):3.
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Brescia AC, Simonds MM, Sullivan KE, Rose CD. Secretion of pro-inflammatory cytokines and chemokines and loss of regulatory signals by fibroblast-like synoviocytes in juvenile idiopathic arthritis. Proteomics Clin Appl. 2017 05; 11(5-6).