"Sodium Channels" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Ion channels that specifically allow the passage of SODIUM ions. A variety of specific sodium channel subtypes are involved in serving specialized functions such as neuronal signaling, CARDIAC MUSCLE contraction, and KIDNEY function.
| Descriptor ID |
D015222
|
| MeSH Number(s) |
D12.776.157.530.400.875 D12.776.543.550.450.875 D12.776.543.585.400.875
|
| Concept/Terms |
Sodium Channels- Sodium Channels
- Channels, Sodium
- Sodium Ion Channels
- Channels, Sodium Ion
- Sodium Channel
- Channel, Sodium
- Ion Channel, Sodium
- Channel, Sodium Ion
- Sodium Ion Channel
- Ion Channels, Sodium
|
Below are MeSH descriptors whose meaning is more general than "Sodium Channels".
Below are MeSH descriptors whose meaning is more specific than "Sodium Channels".
This graph shows the total number of publications written about "Sodium Channels" by people in this website by year, and whether "Sodium Channels" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 3 | 0 | 3 |
| 2008 | 2 | 2 | 4 |
| 2009 | 1 | 1 | 2 |
| 2010 | 5 | 1 | 6 |
| 2011 | 3 | 3 | 6 |
| 2012 | 4 | 0 | 4 |
| 2013 | 2 | 1 | 3 |
| 2014 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 2 | 0 | 2 |
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Below are the most recent publications written about "Sodium Channels" by people in Profiles.
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Burashnikov A. Late INa Inhibition as an Antiarrhythmic Strategy. J Cardiovasc Pharmacol. 2017 Sep; 70(3):159-167.
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Husser D, Ueberham L, Hindricks G, B?ttner P, Ingram C, Weeke P, Shoemaker MB, Adams V, Arya A, Sommer P, Darbar D, Roden DM, Bollmann A. Rare variants in genes encoding the cardiac sodium channel and associated compounds and their impact on outcome of catheter ablation of atrial fibrillation. PLoS One. 2017; 12(8):e0183690.
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Hu D, Barajas-Mart?nez H, Burashnikov A, Panama BK, Cordeiro JM, Antzelevitch C. Mechanisms underlying atrial-selective block of sodium channels by Wenxin Keli: Experimental and theoretical analysis. Int J Cardiol. 2016 Mar 15; 207:326-34.
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Burashnikov A, Di Diego JM, Goodrow RJ, Belardinelli L, Antzelevitch C. Atria are More Sensitive Than Ventricles to GS-458967-Induced Inhibition of Late Sodium Current. J Cardiovasc Pharmacol Ther. 2015 Sep; 20(5):501-8.
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Burashnikov A, Belardinelli L, Antzelevitch C. Inhibition of IKr potentiates development of atrial-selective INa block leading to effective suppression of atrial fibrillation. Heart Rhythm. 2015 Apr; 12(4):836-44.
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Guo D, Yu M, Liu Q, Cox RH, Liu T, Yan GX. Ventricular hypertrophy amplifies transmural dispersion of repolarization by preferentially increasing the late sodium current in endocardium. J Electrocardiol. 2014 Sep-Oct; 47(5):642-8.
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Gao Y, Xue X, Hu D, Liu W, Yuan Y, Sun H, Li L, Timothy KW, Zhang L, Li C, Yan GX. Inhibition of late sodium current by mexiletine: a novel pharmotherapeutical approach in timothy syndrome. Circ Arrhythm Electrophysiol. 2013 Jun; 6(3):614-22.
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Zelle KM, Lu B, Pyfrom SC, Ben-Shahar Y. The genetic architecture of degenerin/epithelial sodium channels in Drosophila. G3 (Bethesda). 2013 Mar; 3(3):441-50.
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Burashnikov A, Antzelevitch C. Role of late sodium channel current block in the management of atrial fibrillation. Cardiovasc Drugs Ther. 2013 Feb; 27(1):79-89.
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Burashnikov A, Barajas-Martinez H, Hu D, Nof E, Blazek J, Antzelevitch C. Atrial-selective prolongation of refractory period with AVE0118 is due principally to inhibition of sodium channel activity. J Cardiovasc Pharmacol. 2012 Jun; 59(6):539-46.