Deoxyribonucleases, Type II Site-Specific
"Deoxyribonucleases, Type II Site-Specific" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Enzyme systems containing a single subunit and requiring only magnesium for endonucleolytic activity. The corresponding modification methylases are separate enzymes. The systems recognize specific short DNA sequences and cleave either within, or at a short specific distance from, the recognition sequence to give specific double-stranded fragments with terminal 5'-phosphates. Enzymes from different microorganisms with the same specificity are called isoschizomers. EC 3.1.21.4.
Descriptor ID |
D015252
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MeSH Number(s) |
D08.811.150.280.260 D08.811.277.352.335.350.300.260 D08.811.277.352.355.325.300.260
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Concept/Terms |
Deoxyribonucleases, Type II Site-Specific- Deoxyribonucleases, Type II Site-Specific
- Deoxyribonucleases, Type II Site Specific
- Deoxyribonucleases, Type II, Site Specific
- Deoxyribonucleases, Type II, Site-Specific
- Type II Site Specific Deoxyribonucleases
- Type II Site-Specific Deoxyribonucleases
- Restriction Endonucleases, Type II
- DNase, Site Specific, Type II
- Site-Specific DNase, Type II
- Site Specific DNase, Type II
- Type II Site Specific DNase
- Type II Site-Specific DNase
- DNase, Site-Specific, Type II
- Type II Restriction Enzymes
- DNA Restriction Enzymes, Type II
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Below are MeSH descriptors whose meaning is more general than "Deoxyribonucleases, Type II Site-Specific".
Below are MeSH descriptors whose meaning is more specific than "Deoxyribonucleases, Type II Site-Specific".
This graph shows the total number of publications written about "Deoxyribonucleases, Type II Site-Specific" by people in this website by year, and whether "Deoxyribonucleases, Type II Site-Specific" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1994 | 0 | 1 | 1 |
2000 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2004 | 2 | 0 | 2 |
2005 | 0 | 2 | 2 |
2006 | 0 | 1 | 1 |
2009 | 0 | 1 | 1 |
2011 | 1 | 0 | 1 |
2016 | 0 | 1 | 1 |
2017 | 0 | 1 | 1 |
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Below are the most recent publications written about "Deoxyribonucleases, Type II Site-Specific" by people in Profiles.
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Khodaverdian VY, Hanscom T, Yu AM, Yu TL, Mak V, Brown AJ, Roberts SA, McVey M. Secondary structure forming sequences drive SD-MMEJ repair of DNA double-strand breaks. Nucleic Acids Res. 2017 Dec 15; 45(22):12848-12861.
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Schipler A, Mladenova V, Soni A, Nikolov V, Saha J, Mladenov E, Iliakis G. Chromosome thripsis by DNA double strand break clusters causes enhanced cell lethality, chromosomal translocations and 53BP1-recruitment. Nucleic Acids Res. 2016 09 19; 44(16):7673-90.
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Liddell L, Manthey G, Pannunzio N, Bailis A. Quantitation and analysis of the formation of HO-endonuclease stimulated chromosomal translocations by single-strand annealing in Saccharomyces cerevisiae. J Vis Exp. 2011 Sep 23; (55).
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Manthey GM, Naik N, Bailis AM. Msh2 blocks an alternative mechanism for non-homologous tail removal during single-strand annealing in Saccharomyces cerevisiae. PLoS One. 2009 Oct 16; 4(10):e7488.
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Iliakis G, Rosidi B, Wang M, Wang H. Plasmid-based assays for DNA end-joining in vitro. Methods Mol Biol. 2006; 314:123-31.
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Rabon-Stith KM, Hagberg JM, Phares DA, Kostek MC, Delmonico MJ, Roth SM, Ferrell RE, Conway JM, Ryan AS, Hurley BF. Vitamin D receptor FokI genotype influences bone mineral density response to strength training, but not aerobic training. Exp Physiol. 2005 Jul; 90(4):653-61.
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Xi J, Zhuang Z, Zhang Z, Selzer T, Spiering MM, Hammes GG, Benkovic SJ. Interaction between the T4 helicase-loading protein (gp59) and the DNA polymerase (gp43): a locking mechanism to delay replication during replisome assembly. Biochemistry. 2005 Feb 22; 44(7):2305-18.
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Tengs T, LaFramboise T, Den RB, Hayes DN, Zhang J, DebRoy S, Gentleman RC, O'Neill K, Birren B, Meyerson M. Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments. Nucleic Acids Res. 2004; 32(15):e121.
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Wang H, Boecker W, Wang H, Wang X, Guan J, Thompson LH, Nickoloff JA, Iliakis G. Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks. Oncogene. 2004 Jan 22; 23(3):824-34.
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Somers KL, Royals MA, Carstea ED, Rafi MA, Wenger DA, Thrall MA. Mutation analysis of feline Niemann-Pick C1 disease. Mol Genet Metab. 2003 Jun; 79(2):99-103.