AIDS Dementia Complex

"AIDS Dementia Complex" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A neurologic condition associated with the ACQUIRED IMMUNODEFICIENCY SYNDROME and characterized by impaired concentration and memory, slowness of hand movements, ATAXIA, incontinence, apathy, and gait difficulties associated with HIV-1 viral infection of the central nervous system. Pathologic examination of the brain reveals white matter rarefaction, perivascular infiltrates of lymphocytes, foamy macrophages, and multinucleated giant cells. (From Adams et al., Principles of Neurology, 6th ed, pp760-1; N Engl J Med, 1995 Apr 6;332(14):934-40)

Descriptor ID	D015526
MeSH Number(s)	C02.782.815.616.400.070 C02.800.801.400.070 C10.228.140.380.070 C20.673.480.070 F03.615.400.050
Concept/Terms	AIDS Dementia Complex AIDS Dementia Complex Complex, AIDS Dementia Dementia Complex, AIDS HIV-Associated Cognitive Motor Complex HIV Associated Cognitive Motor Complex Dementia Complex, Acquired Immune Deficiency Syndrome Acquired-Immune Deficiency Syndrome Dementia Complex AIDS-Related Dementia Complex AIDS Related Dementia Complex HIV Dementia Dementia, HIV Dementias, HIV HIV Dementias Dementia Complex, AIDS-Related Complex, AIDS-Related Dementia Dementia Complex, AIDS Related HIV-1-Associated Cognitive Motor Complex HIV-1-Associated Cognitive Motor Complex HIV 1 Associated Cognitive Motor Complex HIV-1 Cognitive and Motor Complex HIV 1 Cognitive and Motor Complex HIV Encephalopathy HIV Encephalopathy Encephalopathies, HIV HIV Encephalopathies Encephalopathy, AIDS Encephalopathy, HIV AIDS Encephalopathy AIDS Encephalopathies Encephalopathies, AIDS

Below are MeSH descriptors whose meaning is more general than "AIDS Dementia Complex".

Diseases [C]
Virus Diseases [C02]
RNA Virus Infections [C02.782]
Retroviridae Infections [C02.782.815]
Lentivirus Infections [C02.782.815.616]
HIV Infections [C02.782.815.616.400]
AIDS Dementia Complex [C02.782.815.616.400.070]
Sexually Transmitted Diseases [C02.800]
Sexually Transmitted Diseases, Viral [C02.800.801]
HIV Infections [C02.800.801.400]
AIDS Dementia Complex [C02.800.801.400.070]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Brain Diseases [C10.228.140]
Dementia [C10.228.140.380]
AIDS Dementia Complex [C10.228.140.380.070]
Immune System Diseases [C20]
Immunologic Deficiency Syndromes [C20.673]
HIV Infections [C20.673.480]
AIDS Dementia Complex [C20.673.480.070]
Psychiatry and Psychology [F]
Mental Disorders [F03]
Neurocognitive Disorders [F03.615]
Dementia [F03.615.400]
AIDS Dementia Complex [F03.615.400.050]

Below are MeSH descriptors whose meaning is more specific than "AIDS Dementia Complex".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "AIDS Dementia Complex" by people in this website by year, and whether "AIDS Dementia Complex" was a major or minor topic of these publications.

Bar chart showing 16 publications over 12 distinct years, with a maximum of 2 publications in 2003 and 2009 and 2011 and 2019

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2003	1	1	2
2004	1	0	1
2005	0	1	1
2007	1	0	1
2009	1	1	2
2011	2	0	2
2014	1	0	1
2015	1	0	1
2016	1	0	1
2017	1	0	1
2019	1	1	2
2021	1	0	1

Below are the most recent publications written about "AIDS Dementia Complex" by people in Profiles.

Anteraper SA, Gopinath K, Hoch MJ, Waldrop-Valverde D, Franklin D, Letendre SL, Whitfield-Gabrieli S, Anderson AM. A comprehensive data-driven analysis framework for detecting impairments in brain function networks with resting state fMRI in HIV-infected individuals on cART. J Neurovirol. 2021 04; 27(2):239-248.

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Chaganti J, Marripudi K, Staub LP, Rae CD, Gates TM, Moffat KJ, Brew BJ. Imaging correlates of the blood-brain barrier disruption in HIV-associated neurocognitive disorder and therapeutic implications. AIDS. 2019 10 01; 33(12):1843-1852.

View in: PubMed
Jensen BK, Roth LM, Grinspan JB, Jordan-Sciutto KL. White matter loss and oligodendrocyte dysfunction in HIV: A consequence of the infection, the antiretroviral therapy or both? Brain Res. 2019 12 01; 1724:146397.

View in: PubMed
Chaganti JR, Heinecke A, Gates TM, Moffat KJ, Brew BJ. Functional Connectivity in Virally Suppressed Patients with HIV-Associated Neurocognitive Disorder: A Resting-State Analysis. AJNR Am J Neuroradiol. 2017 Aug; 38(8):1623-1629.

View in: PubMed
Gates TM, Cysique LA, Siefried KJ, Chaganti J, Moffat KJ, Brew BJ. Maraviroc-intensified combined antiretroviral therapy improves cognition in virally suppressed HIV-associated neurocognitive disorder. AIDS. 2016 Feb 20; 30(4):591-600.

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Steiner JP, Bachani M, Wolfson-Stofko B, Lee MH, Wang T, Wang T, Li G, Li W, Strayer D, Haughey NJ, Nath A. Interaction of paroxetine with mitochondrial proteins mediates neuroprotection. Neurotherapeutics. 2015 Jan; 12(1):200-16.

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Akay C, Cooper M, Odeleye A, Jensen BK, White MG, Vassoler F, Gannon PJ, Mankowski J, Dorsey JL, Buch AM, Cross SA, Cook DR, Peña MM, Andersen ES, Christofidou-Solomidou M, Lindl KA, Zink MC, Clements J, Pierce RC, Kolson DL, Jordan-Sciutto KL. Antiretroviral drugs induce oxidative stress and neuronal damage in the central nervous system. J Neurovirol. 2014 Feb; 20(1):39-53.

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Louboutin JP, Reyes BA, Agrawal L, Van Bockstaele EJ, Strayer DS. HIV-1 gp120 upregulates matrix metalloproteinases and their inhibitors in a rat model of HIV encephalopathy. Eur J Neurosci. 2011 Dec; 34(12):2015-23.

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Agrawal L, Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS. HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiol Dis. 2012 Feb; 45(2):657-70.

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Agrawal L, Louboutin JP, Marusich E, Reyes BA, Van Bockstaele EJ, Strayer DS. Dopaminergic neurotoxicity of HIV-1 gp120: reactive oxygen species as signaling intermediates. Brain Res. 2010 Jan 8; 1306:116-30.

View in: PubMed

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