Below are the most recent publications written about "Platelet Activation" by people in Profiles.
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Kulkarni PP, Alluri RK, Godwin M, Forbes GL, Merkulova A, Lambert S, Vijay A, Palihati M, Kundu S, Shim YJ, Kalonji K, Schmaier AH, Holinstat M, Cameron SJ, McCrae KR. Protection of ?2GPI-deficient mice from thrombosis reflects a defect in PAR3-facilitated platelet activation. Blood. 2025 May 01; 145(18):2086-2099.
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Rodriguez A, Yu M, Phoo MT, Holinstat M, Schwendeman A. Antiplatelet Effects of DMPC-Based Synthetic High-Density Lipoproteins: Exploring Particle Structure and Noncholesterol Efflux Mechanisms. Mol Pharm. 2025 Mar 03; 22(3):1305-1317.
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Leung HHL, Ahmadi Z, Lee B, Casey J, Ratnasingam S, McKenzie SE, Perdomo J, Chong BH. Antithrombotic efficacy and bleeding risks of vaccine-induced immune thrombotic thrombocytopenia treatments. Blood Adv. 2024 11 26; 8(22):5744-5752.
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Nigam A, Manjuprasanna VN, Naik MU, Naik UP. Platelet spreading and clot retraction are regulated by 2 distinct aIIb?3 outside-in signaling pathways. J Pharmacol Exp Ther. 2025 Jan; 392(1):100012.
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Goerger K, Caldwell M, Biermann G, Besh F, Flickema T, Patel P, Abbott K, Holinstat M, Larson MK. Observational Analyses of Ex Vivo Native American Platelet Responses. Int J Mol Sci. 2024 Nov 08; 25(22).
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Han X, Knauss EA, Fuente M, Li W, Conlon RA, LePage DF, Jiang W, Renna SA, McKenzie SE, Nieman MT. A mouse model of the protease-activated receptor 4 Pro310Leu variant has reduced platelet reactivity. J Thromb Haemost. 2024 Jun; 22(6):1715-1726.
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Stanger L, Yamaguchi A, Yalavarthi P, Lambert S, Gilmore D, Rickenberg A, Luke C, Kumar K, Obi AT, White A, Bergh N, Dahl?f B, Holinstat M. The oxylipin analog CS585 prevents platelet activation and thrombosis through activation of the prostacyclin receptor. Blood. 2023 11 02; 142(18):1556-1569.
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Mobbs JI, Black KA, Tran M, Burger WAC, Venugopal H, Holman TR, Holinstat M, Thal DM, Glukhova A. Cryo-EM structures of human arachidonate 12S-lipoxygenase bound to endogenous and exogenous inhibitors. Blood. 2023 10 05; 142(14):1233-1242.
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Dangelmaier CA, Patchin M, Vajipayajula DN, Vari HR, Singh PK, Wright MN, Kostyak JC, Tsygankov AY, Kunapuli SP. Phosphorylation of spleen tyrosine kinase at Y346 negatively regulates ITAM-mediated signaling and function in platelets. J Biol Chem. 2023 07; 299(7):104865.
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Downes K, Zhao X, Gleadall NS, McKinney H, Kempster C, Batista J, Thomas PL, Cooper M, Michael JV, Kreuzhuber R, Wedderburn K, Waller K, Varney B, Verdier H, Kriek N, Ashford SE, Stirrups KE, Dunster JL, McKenzie SE, Ouwehand WH, Gibbins JM, Yang J, Astle WJ, Ma P. G protein-coupled receptor kinase 5 regulates thrombin signaling in platelets via PAR-1. Blood Adv. 2022 04 12; 6(7):2319-2330.