Fatigue Syndrome, Chronic

"Fatigue Syndrome, Chronic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A syndrome characterized by persistent or recurrent fatigue, diffuse musculoskeletal pain, sleep disturbances, and subjective cognitive impairment of 6 months duration or longer. Symptoms are not caused by ongoing exertion; are not relieved by rest; and result in a substantial reduction of previous levels of occupational, educational, social, or personal activities. Minor alterations of immune, neuroendocrine, and autonomic function may be associated with this syndrome. There is also considerable overlap between this condition and FIBROMYALGIA. (From Semin Neurol 1998;18(2):237-42; Ann Intern Med 1994 Dec 15;121(12): 953-9)

Descriptor ID	D015673
MeSH Number(s)	C02.330 C05.651.310 C10.228.440.600 C10.668.364
Concept/Terms	Fatigue Syndrome, Chronic Fatigue Syndrome, Chronic Myalgic Encephalomyelitis Encephalomyelitis, Myalgic Chronic Fatigue Syndrome Chronic Fatigue Syndromes Fatigue Syndromes, Chronic Chronic Fatigue-Fibromyalgia Syndrome Chronic Fatigue Fibromyalgia Syndrome Chronic Fatigue-Fibromyalgia Syndromes Fatigue-Fibromyalgia Syndrome, Chronic Fatigue-Fibromyalgia Syndromes, Chronic Postviral Fatigue Syndrome Infectious Mononucleosis-Like Syndrome, Chronic Infectious Mononucleosis Like Syndrome, Chronic Royal Free Disease Chronic Fatigue and Immune Dysfunction Syndrome Chronic Fatigue Disorder Chronic Fatigue Disorders Fatigue Disorder, Chronic Fatigue Disorders, Chronic Systemic Exertion Intolerance Disease Fatigue Syndrome, Postviral Fatigue Syndromes, Postviral Postviral Fatigue Syndromes

Below are MeSH descriptors whose meaning is more general than "Fatigue Syndrome, Chronic".

Diseases [C]
Virus Diseases [C02]
Fatigue Syndrome, Chronic [C02.330]
Musculoskeletal Diseases [C05]
Muscular Diseases [C05.651]
Fatigue Syndrome, Chronic [C05.651.310]
Nervous System Diseases [C10]
Central Nervous System Diseases [C10.228]
Encephalomyelitis [C10.228.440]
Fatigue Syndrome, Chronic [C10.228.440.600]
Neuromuscular Diseases [C10.668]
Fatigue Syndrome, Chronic [C10.668.364]

Below are MeSH descriptors whose meaning is related to "Fatigue Syndrome, Chronic".

Below are MeSH descriptors whose meaning is more specific than "Fatigue Syndrome, Chronic".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Fatigue Syndrome, Chronic" by people in this website by year, and whether "Fatigue Syndrome, Chronic" was a major or minor topic of these publications.

Bar chart showing 11 publications over 9 distinct years, with a maximum of 2 publications in 2009 and 2024

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	1	0	1
2004	1	0	1
2006	1	0	1
2007	0	1	1
2009	0	2	2
2011	1	0	1
2013	1	0	1
2016	0	1	1
2024	1	1	2

Below are the most recent publications written about "Fatigue Syndrome, Chronic" by people in Profiles.

Angeles MR, Dinh TTN, Zhao T, de Graaff B, Hensher M. The economic burden of long COVID in Australia: more noise than signal? Med J Aust. 2024 Nov 04; 221 Suppl 9:S31-S39.

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Unger ER, Lin JS, Wisk LE, Yu H, L'Hommedieu M, Lavretsky H, Montoy JCC, Gottlieb MA, Rising KL, Gentile NL, Santangelo M, Venkatesh AK, Rodriguez RM, Hill MJ, Geyer RE, Kean ER, Saydah S, McDonald SA, Huebinger R, Idris AH, Dorney J, Hota B, Spatz ES, Stephens KA, Weinstein RA, Elmore JG. Myalgic Encephalomyelitis/Chronic Fatigue Syndrome After SARS-CoV-2 Infection. JAMA Netw Open. 2024 Jul 01; 7(7):e2423555.

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Pavlik D, Agnew D, Stiles L, Ditoro R. Recognizing postural orthostatic tachycardia syndrome. JAAPA. 2016 Apr; 29(4):17-23.

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Mitchell WM, Nicodemus CF, Carter WA, Horvath JC, Strayer DR. Discordant biological and toxicological species responses to TLR3 activation. Am J Pathol. 2014 Apr; 184(4):1062-1072.

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Richardson G, Epstein D, Chew-Graham C, Dowrick C, Bentall RP, Morriss RK, Peters S, Riste L, Lovell K, Dunn G, Wearden AJ. Cost-effectiveness of supported self-management for CFS/ME patients in primary care. BMC Fam Pract. 2013 Jan 18; 14:12.

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Tietjen GE, Brandes JL, Peterlin BL, Eloff A, Dafer RM, Stein MR, Drexler E, Martin VT, Hutchinson S, Aurora SK, Recober A, Herial NA, Utley C, White L, Khuder SA. Childhood maltreatment and migraine (part III). Association with comorbid pain conditions. Headache. 2010 Jan; 50(1):42-51.

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Tietjen GE, Brandes JL, Peterlin BL, Eloff A, Dafer RM, Stein MR, Drexler E, Martin VT, Hutchinson S, Aurora SK, Recober A, Herial NA, Utley C, White L, Khuder SA. Allodynia in migraine: association with comorbid pain conditions. Headache. 2009 Oct; 49(9):1333-44.

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Tietjen GE, Herial NA, Hardgrove J, Utley C, White L. Migraine comorbidity constellations. Headache. 2007 Jun; 47(6):857-65.

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Deluca J, Christodoulou C, Diamond BJ, Rosenstein ED, Kramer N, Natelson BH. Working memory deficits in chronic fatigue syndrome: differentiating between speed and accuracy of information processing. J Int Neuropsychol Soc. 2004 Jan; 10(1):101-9.

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Dalakas MC. Enteroviruses in chronic fatigue syndrome: "now you see them, now you don't". J Neurol Neurosurg Psychiatry. 2003 Oct; 74(10):1361-2.

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