"RNA, Antisense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
RNA molecules which hybridize to complementary sequences in either RNA or DNA altering the function of the latter. Endogenous antisense RNAs function as regulators of gene expression by a variety of mechanisms. Synthetic antisense RNAs are used to effect the functioning of specific genes for investigative or therapeutic purposes.
| Descriptor ID |
D016372
|
| MeSH Number(s) |
D13.150.650 D13.444.600.150.760 D13.444.735.150 D27.720.470.530.600.150.760
|
| Concept/Terms |
RNA, Antisense- RNA, Antisense
- Antisense RNA
- Anti-Sense RNA
- Anti Sense RNA
- RNA, Anti-Sense
|
Below are MeSH descriptors whose meaning is more general than "RNA, Antisense".
Below are MeSH descriptors whose meaning is more specific than "RNA, Antisense".
This graph shows the total number of publications written about "RNA, Antisense" by people in this website by year, and whether "RNA, Antisense" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 2 | 2 |
| 2002 | 1 | 0 | 1 |
| 2003 | 2 | 1 | 3 |
| 2004 | 0 | 1 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2010 | 1 | 0 | 1 |
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click here.
Below are the most recent publications written about "RNA, Antisense" by people in Profiles.
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Borden JR, Jones SW, Indurthi D, Chen Y, Papoutsakis ET. A genomic-library based discovery of a novel, possibly synthetic, acid-tolerance mechanism in Clostridium acetobutylicum involving non-coding RNAs and ribosomal RNA processing. Metab Eng. 2010 May; 12(3):268-81.
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Hudak JJ, Killeen E, Chandran A, Cohen JC, Larson JE. Adult onset lung disease following transient disruption of fetal stretch-induced differentiation. Respir Res. 2009 May 06; 10:34.
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Gad A, Callender DL, Killeen E, Hudak J, Dlugosz MA, Larson JE, Cohen JC, Chander A. Transient in utero disruption of cystic fibrosis transmembrane conductance regulator causes phenotypic changes in alveolar type II cells in adult rats. BMC Cell Biol. 2009 Mar 31; 10:24.
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Ocaranza P, Quintanilla ME, Tampier L, Karahanian E, Sapag A, Israel Y. Gene therapy reduces ethanol intake in an animal model of alcohol dependence. Alcohol Clin Exp Res. 2008 Jan; 32(1):52-7.
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Ezquer F, N??ez MT, Rojas A, Asenjo J, Israel Y. Hereditary hemochromatosis: an opportunity for gene therapy. Biol Res. 2006; 39(1):113-24.
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Karahanian E, Ocaranza P, Israel Y. Aldehyde dehydrogenase (ALDH2) activity in hepatoma cells is reduced by an adenoviral vector coding for an ALDH2 antisense mRNA. Alcohol Clin Exp Res. 2005 Aug; 29(8):1384-9.
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Ezquer F, N??ez MT, Israel Y. Antisense gene delivered by an adenoassociated viral vector inhibits iron uptake in human intestinal cells: potential application in hemochromatosis. Biochem Pharmacol. 2005 Jun 01; 69(11):1559-66.
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O'Hara SM, Moreno JG, Zweitzig DR, Gross S, Gomella LG, Terstappen LW. Multigene reverse transcription-PCR profiling of circulating tumor cells in hormone-refractory prostate cancer. Clin Chem. 2004 May; 50(5):826-35.
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Toren A, Rozenfeld-Granot G, Heath KE, Amariglio N, Rocca B, Crosson J, Epstein CJ, Laghi F, Landolfi R, Carlsson LE, Argraves S, Bizzaro N, Moxey-Mims M, Brok-Simoni F, Martignetti JA, Greinacher A, Rechavi G. MYH9 spectrum of autosomal-dominant giant platelet syndromes: unexpected association with fibulin-1 variant-D inactivation. Am J Hematol. 2003 Dec; 74(4):254-62.
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Tummala SB, Junne SG, Papoutsakis ET. Antisense RNA downregulation of coenzyme A transferase combined with alcohol-aldehyde dehydrogenase overexpression leads to predominantly alcohologenic Clostridium acetobutylicum fermentations. J Bacteriol. 2003 Jun; 185(12):3644-53.