"DNA, Antisense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
| Descriptor ID |
D016373
|
| MeSH Number(s) |
D13.150.200 D13.444.308.150 D13.444.600.150.200 D27.720.470.530.600.150.200
|
| Concept/Terms |
DNA, Antisense- DNA, Antisense
- Anti-Sense DNA
- Anti Sense DNA
- DNA, Anti-Sense
- Antisense DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Antisense".
Below are MeSH descriptors whose meaning is more specific than "DNA, Antisense".
This graph shows the total number of publications written about "DNA, Antisense" by people in this website by year, and whether "DNA, Antisense" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
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Below are the most recent publications written about "DNA, Antisense" by people in Profiles.
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Hudak JJ, Killeen E, Chandran A, Cohen JC, Larson JE. Adult onset lung disease following transient disruption of fetal stretch-induced differentiation. Respir Res. 2009 May 06; 10:34.
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Lai SY, Koppikar P, Thomas SM, Childs EE, Egloff AM, Seethala RR, Branstetter BF, Gooding WE, Muthukrishnan A, Mountz JM, Lui VW, Shin DM, Agarwala SS, Johnson R, Couture LA, Myers EN, Johnson JT, Mills G, Argiris A, Grandis JR. Intratumoral epidermal growth factor receptor antisense DNA therapy in head and neck cancer: first human application and potential antitumor mechanisms. J Clin Oncol. 2009 Mar 10; 27(8):1235-42.
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Cohen JC, Scott DK, Miller J, Zhang J, Zhou P, Larson JE. Transient in utero knockout (TIUKO) of C-MYC affects late lung and intestinal development in the mouse. BMC Dev Biol. 2004 Apr 16; 4:4.
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Masciullo V, Baldassarre G, Pentimalli F, Berlingieri MT, Boccia A, Chiappetta G, Palazzo J, Manfioletti G, Giancotti V, Viglietto G, Scambia G, Fusco A. HMGA1 protein over-expression is a frequent feature of epithelial ovarian carcinomas. Carcinogenesis. 2003 Jul; 24(7):1191-8.
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Ponnappa BC, Israel Y. Targeting Kupffer cells with antisense oligonucleotides. Front Biosci. 2002 May 01; 7:e223-33.
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Graeven U, Fiedler W, Karpinski S, Ergün S, Kilic N, Rodeck U, Schmiegel W, Hossfeld DK. Melanoma-associated expression of vascular endothelial growth factor and its receptors FLT-1 and KDR. J Cancer Res Clin Oncol. 1999 Nov; 125(11):621-9.
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Galbiati F, Volonte D, Engelman JA, Watanabe G, Burk R, Pestell RG, Lisanti MP. Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade. EMBO J. 1998 Nov 16; 17(22):6633-48.