Eosinophilia-Myalgia Syndrome
"Eosinophilia-Myalgia Syndrome" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A complex systemic syndrome with inflammatory and autoimmune components that affect the skin, fascia, muscle, nerve, blood vessels, lung, and heart. Diagnostic features generally include EOSINOPHILIA, myalgia severe enough to limit usual activities of daily living, and the absence of coexisting infectious, autoimmune or other conditions that may induce eosinophilia. Biopsy of affected tissue reveals a microangiopathy associated with diffuse inflammation involving connective tissue. (From Spitzer et al., J Rheumatol Suppl 1996 Oct;46:73-9; Blackburn WD, Semin Arthritis Rheum 1997 Jun;26(6):788-93)
Descriptor ID |
D016603
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MeSH Number(s) |
C05.651.290 C10.668.491.387 C15.378.553.231.335
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Concept/Terms |
Eosinophilia-Myalgia Syndrome- Eosinophilia-Myalgia Syndrome
- Eosinophilia Myalgia Syndrome
- Eosinophilia-Myalgia Syndromes
- Syndrome, Eosinophilia-Myalgia
- Syndromes, Eosinophilia-Myalgia
Eosinophilia-Myalgia Syndrome, L-Tryptophan-Related- Eosinophilia-Myalgia Syndrome, L-Tryptophan-Related
- Eosinophilia-Myalgia Syndromes, L-Tryptophan-Related
- L-Tryptophan-Related Eosinophilia-Myalgia Syndromes
- Syndrome, L-Tryptophan-Related Eosinophilia-Myalgia
- Syndromes, L-Tryptophan-Related Eosinophilia-Myalgia
- Syndrome, Eosinophilia-Myalgia, L-Tryptophan-Related
- L-Tryptophan-Related Eosinophilia-Myalgia Syndrome
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Below are MeSH descriptors whose meaning is more general than "Eosinophilia-Myalgia Syndrome".
Below are MeSH descriptors whose meaning is more specific than "Eosinophilia-Myalgia Syndrome".
This graph shows the total number of publications written about "Eosinophilia-Myalgia Syndrome" by people in this website by year, and whether "Eosinophilia-Myalgia Syndrome" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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1995 | 1 | 0 | 1 |
1997 | 1 | 0 | 1 |
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Below are the most recent publications written about "Eosinophilia-Myalgia Syndrome" by people in Profiles.
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Hitraya EG, Jimenez SA, Ludwicka A, Silver RM, Varga J. Increased activity of the alpha 1(I) procollagen promoter in skin fibroblasts from patients with chronic eosinophilia-myalgia syndrome. Int J Biochem Cell Biol. 1997 Jan; 29(1):135-41.
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Kaufman LD, Varga J, Gomez-Reino JJ, Jimenez S, Targoff IN. Autoantibodies in sera from patients with L-tryptophan-associated eosinophilia-myalgia syndrome. Demonstration of unique antigen-antibody specificities. Clin Immunol Immunopathol. 1995 Aug; 76(2):115-9.
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Varga J, Jimenez SA. Chemical exposure-induced cutaneous fibrosis. Lessons from 'experiments of nature'. Arch Dermatol. 1994 Jan; 130(1):97-100.
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Varga J, Li L, Jimenez SA. Increased type I collagen gene expression in L-tryptophan associated eosinophilia-myalgia syndrome skin fibroblasts. J Rheumatol. 1993 Aug; 20(8):1303-8.
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Illa I, Dinsmore S, Dalakas MC. Immune-mediated mechanisms and immune activation of fibroblasts in the pathogenesis of eosinophilia-myalgia syndrome induced by L-tryptophan. Hum Pathol. 1993 Jul; 24(7):702-9.
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Reitamo S, Remitz A, Varga J, Ceska M, Effenberger F, Jimenez S, Uitto J. Demonstration of interleukin 8 and autoantibodies to interleukin 8 in the serum of patients with systemic sclerosis and related disorders. Arch Dermatol. 1993 Feb; 129(2):189-93.
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Varga J, Jimenez SA, Uitto J. L-tryptophan and the eosinophilia-myalgia syndrome: current understanding of the etiology and pathogenesis. J Invest Dermatol. 1993 Jan; 100(1):97S-105S.
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Uitto J, Varga J, Peltonen J, Jimenez SA. Eosinophilia-myalgia syndrome. Int J Dermatol. 1992 Apr; 31(4):223-8.
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Varga J, Uitto J, Jimenez SA. The cause and pathogenesis of the eosinophilia-myalgia syndrome. Ann Intern Med. 1992 Jan 15; 116(2):140-7.
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Varga J, Maul GG, Jimenez SA. Autoantibodies to nuclear lamin C in the eosinophilia-myalgia syndrome associated with L-tryptophan ingestion. Arthritis Rheum. 1992 Jan; 35(1):106-9.