Immediate-Early Proteins

"Immediate-Early Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins that are coded by immediate-early genes, in the absence of de novo protein synthesis. The term was originally used exclusively for viral regulatory proteins that were synthesized just after viral integration into the host cell. It is also used to describe cellular proteins which are synthesized immediately after the resting cell is stimulated by extracellular signals.

Descriptor ID	D017874
MeSH Number(s)	D12.776.460 D12.776.964.925.968
Concept/Terms	Immediate-Early Proteins Immediate-Early Proteins Immediate Early Proteins Proteins, Immediate-Early Proteins, Immediate Early

Below are MeSH descriptors whose meaning is more general than "Immediate-Early Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
Immediate-Early Proteins [D12.776.460]
Viral Proteins [D12.776.964]
Viral Regulatory and Accessory Proteins [D12.776.964.925]
Immediate-Early Proteins [D12.776.964.925.968]

Below are MeSH descriptors whose meaning is related to "Immediate-Early Proteins".

Below are MeSH descriptors whose meaning is more specific than "Immediate-Early Proteins".

Immediate-Early Proteins
Adenovirus E1 Proteins
Butyrate Response Factor 1
Early Growth Response Transcription Factors
Tristetraprolin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Immediate-Early Proteins" by people in this website by year, and whether "Immediate-Early Proteins" was a major or minor topic of these publications.

Bar chart showing 19 publications over 12 distinct years, with a maximum of 4 publications in 2004 and 2006

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1995	1	0	1
1998	1	0	1
1999	1	0	1
2001	1	0	1
2002	1	0	1
2003	1	0	1
2004	2	2	4
2005	2	0	2
2006	3	1	4
2009	0	1	1
2011	0	1	1
2014	1	0	1

Below are the most recent publications written about "Immediate-Early Proteins" by people in Profiles.

Jiao Y, Ye DZ, Li Z, Teta-Bissett M, Peng Y, Taub R, Greenbaum LE, Kaestner KH. Protein tyrosine phosphatase of liver regeneration-1 is required for normal timing of cell cycle progression during liver regeneration. Am J Physiol Gastrointest Liver Physiol. 2015 Jan 15; 308(2):G85-91.

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Snyder CM, Cho KS, Bonnett EL, Allan JE, Hill AB. Sustained CD8+ T cell memory inflation after infection with a single-cycle cytomegalovirus. PLoS Pathog. 2011 Oct; 7(10):e1002295.

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Snyder CM, Loewendorf A, Bonnett EL, Croft M, Benedict CA, Hill AB. CD4+ T cell help has an epitope-dependent impact on CD8+ T cell memory inflation during murine cytomegalovirus infection. J Immunol. 2009 Sep 15; 183(6):3932-41.

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Kennedy L, Liu S, Shi-Wen X, Chen Y, Eastwood M, Sabetkar M, Carter DE, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for the function of mouse embryonic fibroblasts. Exp Cell Res. 2007 Mar 10; 313(5):952-64.

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Kawakubo H, Brachtel E, Hayashida T, Yeo G, Kish J, Muzikansky A, Walden PD, Maheswaran S. Loss of B-cell translocation gene-2 in estrogen receptor-positive breast carcinoma is associated with tumor grade and overexpression of cyclin d1 protein. Cancer Res. 2006 Jul 15; 66(14):7075-82.

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Codony-Servat J, Tapia MA, Bosch M, Oliva C, Domingo-Domenech J, Mellado B, Rolfe M, Ross JS, Gascon P, Rovira A, Albanell J. Differential cellular and molecular effects of bortezomib, a proteasome inhibitor, in human breast cancer cells. Mol Cancer Ther. 2006 Mar; 5(3):665-75.

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Shi-wen X, Stanton LA, Kennedy L, Pala D, Chen Y, Howat SL, Renzoni EA, Carter DE, Bou-Gharios G, Stratton RJ, Pearson JD, Beier F, Lyons KM, Black CM, Abraham DJ, Leask A. CCN2 is necessary for adhesive responses to transforming growth factor-beta1 in embryonic fibroblasts. J Biol Chem. 2006 Apr 21; 281(16):10715-26.

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Abrams MT, Robertson NM, Litwack G, Wickstrom E. Evaluation of glucocorticoid sensitivity in 697 pre-B acute lymphoblastic leukemia cells after overexpression or silencing of MAP kinase phosphatase-1. J Cancer Res Clin Oncol. 2005 Jun; 131(6):347-54.

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Zhou D, Herrick DJ, Rosenbloom J, Chaqour B. Cyr61 mediates the expression of VEGF, alphav-integrin, and alpha-actin genes through cytoskeletally based mechanotransduction mechanisms in bladder smooth muscle cells. J Appl Physiol (1985). 2005 Jun; 98(6):2344-54.

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Han WK, Bonventre JV. Biologic markers for the early detection of acute kidney injury. Curr Opin Crit Care. 2004 Dec; 10(6):476-82.

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