Antigen Presentation

"Antigen Presentation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process by which antigen is presented to lymphocytes in a form they can recognize. This is performed by antigen presenting cells (APCs). Some antigens require processing before they can be recognized. Antigen processing consists of ingestion and partial digestion of the antigen by the APC, followed by presentation of fragments on the cell surface. (From Rosen et al., Dictionary of Immunology, 1989)

Descriptor ID	D017951
MeSH Number(s)	G12.119 G12.450.050.400.070
Concept/Terms	Antigen Presentation Antigen Presentation Antigen Presentations Antigen Processing Antigen Processing Antigen Processings

Below are MeSH descriptors whose meaning is more general than "Antigen Presentation".

Biological Sciences [G]
Immune System Phenomena [G12]
Antigen Presentation [G12.119]
Immunity [G12.450]
Adaptive Immunity [G12.450.050]
Immunity, Cellular [G12.450.050.400]
Antigen Presentation [G12.450.050.400.070]

Below are MeSH descriptors whose meaning is related to "Antigen Presentation".

Below are MeSH descriptors whose meaning is more specific than "Antigen Presentation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigen Presentation" by people in this website by year, and whether "Antigen Presentation" was a major or minor topic of these publications.

Bar chart showing 71 publications over 23 distinct years, with a maximum of 8 publications in 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1999	1	0	1
2000	1	0	1
2001	0	1	1
2002	5	0	5
2003	4	3	7
2004	3	3	6
2005	4	3	7
2006	2	2	4
2007	1	2	3
2008	3	1	4
2009	3	5	8
2010	2	1	3
2011	3	4	7
2012	2	1	3
2013	0	1	1
2014	1	1	2
2016	0	1	1
2017	0	2	2
2018	0	1	1
2020	0	1	1
2021	1	0	1
2022	0	1	1
2023	1	0	1

Below are the most recent publications written about "Antigen Presentation" by people in Profiles.

Scharrig E, Mantegazza AR. Dissecting Phagosomal Pattern Recognition Receptor-Dependent Signaling and Antigen MHC-II Presentation from Phagosomes in Murine?Dendritic Cells. Methods Mol Biol. 2023; 2692:275-287.

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Addison MM, Ellis GI, Leslie GJ, Zawadzky NB, Riley JL, Hoxie JA, Eisenlohr LC. HIV-1-Infected CD4+ T Cells Present MHC Class II-Restricted Epitope via Endogenous Processing. J Immunol. 2022 09 01; 209(5):864-873.

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Toulmin SA, Bhadiadra C, Paris AJ, Lin JH, Katzen J, Basil MC, Morrisey EE, Worthen GS, Eisenlohr LC. Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation. Nat Commun. 2021 06 28; 12(1):3993.

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Levin-Konigsberg R, Mantegazza AR. A guide to measuring phagosomal dynamics. FEBS J. 2021 03; 288(5):1412-1433.

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Soni C, Schell SL, Fasnacht MJ, Chodisetti SB, Rahman ZS. Crucial role of Mer tyrosine kinase in the maintenance of SIGN-R1+ marginal zone macrophages. Immunol Cell Biol. 2018 03; 96(3):298-315.

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Niu C, Li L, Daffis S, Lucifora J, Bonnin M, Maadadi S, Salas E, Chu R, Ramos H, Livingston CM, Beran RK, Garg AV, Balsitis S, Durantel D, Zoulim F, Delaney WE, Fletcher SP. Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism. J Hepatol. 2018 05; 68(5):922-931.

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Schell SL, Soni C, Fasnacht MJ, Domeier PP, Cooper TK, Rahman ZSM. Mer Receptor Tyrosine Kinase Signaling Prevents Self-Ligand Sensing and Aberrant Selection in Germinal Centers. J Immunol. 2017 12 15; 199(12):4001-4015.

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Wiest DL. Development of ?d T Cells, the Special-Force Soldiers of the Immune System. Methods Mol Biol. 2016; 1323:23-32.

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Mantegazza AR, Zajac AL, Twelvetrees A, Holzbaur EL, Amigorena S, Marks MS. TLR-dependent phagosome tubulation in dendritic cells promotes phagosome cross-talk to optimize MHC-II antigen presentation. Proc Natl Acad Sci U S A. 2014 Oct 28; 111(43):15508-13.

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Ngo MC, Ando J, Leen AM, Ennamuri S, Lapteva N, Vera JF, Min-Venditti A, Mims MP, Heslop HE, Bollard CM, Gottschalk S, Rooney CM. Complementation of antigen-presenting cells to generate T lymphocytes with broad target specificity. J Immunother. 2014 May; 37(4):193-203.

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