"Antigen Presentation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The process by which antigen is presented to lymphocytes in a form they can recognize. This is performed by antigen presenting cells (APCs). Some antigens require processing before they can be recognized. Antigen processing consists of ingestion and partial digestion of the antigen by the APC, followed by presentation of fragments on the cell surface. (From Rosen et al., Dictionary of Immunology, 1989)
| Descriptor ID |
D017951
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| MeSH Number(s) |
G12.119 G12.450.050.400.070
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Antigen Presentation".
Below are MeSH descriptors whose meaning is more specific than "Antigen Presentation".
This graph shows the total number of publications written about "Antigen Presentation" by people in this website by year, and whether "Antigen Presentation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2001 | 2 | 1 | 3 |
| 2002 | 3 | 1 | 4 |
| 2003 | 1 | 2 | 3 |
| 2004 | 1 | 2 | 3 |
| 2005 | 3 | 2 | 5 |
| 2006 | 1 | 2 | 3 |
| 2007 | 2 | 1 | 3 |
| 2008 | 1 | 1 | 2 |
| 2009 | 0 | 3 | 3 |
| 2010 | 1 | 1 | 2 |
| 2011 | 3 | 3 | 6 |
| 2012 | 1 | 0 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 2 | 2 |
| 2015 | 1 | 1 | 2 |
| 2016 | 2 | 1 | 3 |
| 2017 | 1 | 3 | 4 |
| 2018 | 0 | 2 | 2 |
| 2019 | 1 | 1 | 2 |
| 2020 | 3 | 0 | 3 |
| 2021 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Antigen Presentation" by people in Profiles.
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Addison MM, Ellis GI, Leslie GJ, Zawadzky NB, Riley JL, Hoxie JA, Eisenlohr LC. HIV-1-Infected CD4+ T Cells Present MHC Class II-Restricted Epitope via Endogenous Processing. J Immunol. 2022 09 01; 209(5):864-873.
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Toulmin SA, Bhadiadra C, Paris AJ, Lin JH, Katzen J, Basil MC, Morrisey EE, Worthen GS, Eisenlohr LC. Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation. Nat Commun. 2021 06 28; 12(1):3993.
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Forsyth KS, Roy NH, Peauroi E, DeHaven BC, Wold ED, Hersperger AR, Burkhardt JK, Eisenlohr LC. Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+?T cells post peptide loading. PLoS Pathog. 2020 08; 16(8):e1008685.
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Cosma GL, Lobby JL, Fay EJ, Siciliano NA, Langlois RA, Eisenlohr LC. Kinetically distinct processing pathways diversify the CD8+ T cell response to a single viral epitope. Proc Natl Acad Sci U S A. 2020 08 11; 117(32):19399-19407.
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Cho KJ, Ishido S, Eisenlohr LC, Roche PA. Activation of Dendritic Cells Alters the Mechanism of MHC Class II Antigen Presentation to CD4 T Cells. J Immunol. 2020 03 15; 204(6):1621-1629.
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Cosma GL, Eisenlohr LC. Impact of epitope density on CD8+ T cell development and function. Mol Immunol. 2019 09; 113:120-125.
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Forsyth KS, DeHaven B, Mendonca M, Paul S, Sette A, Eisenlohr LC. Poor Antigen Processing of Poxvirus Particles Limits CD4+ T Cell Recognition and Impacts Immunogenicity of the Inactivated Vaccine. J Immunol. 2019 03 01; 202(5):1340-1349.
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Wang TT, Bournazos S, Ravetch JV. Immunological responses to influenza vaccination: lessons for improving vaccine efficacy. Curr Opin Immunol. 2018 08; 53:124-129.
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Soni C, Schell SL, Fasnacht MJ, Chodisetti SB, Rahman ZS. Crucial role of Mer tyrosine kinase in the maintenance of SIGN-R1+ marginal zone macrophages. Immunol Cell Biol. 2018 03; 96(3):298-315.
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Niu C, Li L, Daffis S, Lucifora J, Bonnin M, Maadadi S, Salas E, Chu R, Ramos H, Livingston CM, Beran RK, Garg AV, Balsitis S, Durantel D, Zoulim F, Delaney WE, Fletcher SP. Toll-like receptor 7 agonist GS-9620 induces prolonged inhibition of HBV via a type I interferon-dependent mechanism. J Hepatol. 2018 05; 68(5):922-931.