Antigen Presentation

"Antigen Presentation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The process by which antigen is presented to lymphocytes in a form they can recognize. This is performed by antigen presenting cells (APCs). Some antigens require processing before they can be recognized. Antigen processing consists of ingestion and partial digestion of the antigen by the APC, followed by presentation of fragments on the cell surface. (From Rosen et al., Dictionary of Immunology, 1989)

Descriptor ID	D017951
MeSH Number(s)	G12.119 G12.450.050.400.070
Concept/Terms	Antigen Presentation Antigen Presentation Antigen Presentations Antigen Processing Antigen Processing Antigen Processings

Below are MeSH descriptors whose meaning is more general than "Antigen Presentation".

Biological Sciences [G]
Immune System Phenomena [G12]
Antigen Presentation [G12.119]
Immunity [G12.450]
Adaptive Immunity [G12.450.050]
Immunity, Cellular [G12.450.050.400]
Antigen Presentation [G12.450.050.400.070]

Below are MeSH descriptors whose meaning is related to "Antigen Presentation".

Below are MeSH descriptors whose meaning is more specific than "Antigen Presentation".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Antigen Presentation" by people in this website by year, and whether "Antigen Presentation" was a major or minor topic of these publications.

Bar chart showing 107 publications over 27 distinct years, with a maximum of 8 publications in 2003 and 2009

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1996	0	1	1
1998	2	1	3
1999	2	1	3
2000	4	0	4
2001	2	3	5
2002	5	1	6
2003	4	4	8
2004	3	3	6
2005	4	3	7
2006	2	2	4
2007	2	2	4
2008	3	1	4
2009	3	5	8
2010	2	1	3
2011	3	4	7
2012	3	1	4
2013	1	3	4
2014	1	2	3
2015	1	2	3
2016	2	2	4
2017	1	3	4
2018	0	2	2
2019	1	1	2
2020	3	1	4
2021	2	0	2
2022	0	1	1
2023	1	0	1

Below are the most recent publications written about "Antigen Presentation" by people in Profiles.

Scharrig E, Mantegazza AR. Dissecting Phagosomal Pattern Recognition Receptor-Dependent Signaling and Antigen MHC-II Presentation from Phagosomes in Murine?Dendritic Cells. Methods Mol Biol. 2023; 2692:275-287.

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Addison MM, Ellis GI, Leslie GJ, Zawadzky NB, Riley JL, Hoxie JA, Eisenlohr LC. HIV-1-Infected CD4+ T Cells Present MHC Class II-Restricted Epitope via Endogenous Processing. J Immunol. 2022 09 01; 209(5):864-873.

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Toulmin SA, Bhadiadra C, Paris AJ, Lin JH, Katzen J, Basil MC, Morrisey EE, Worthen GS, Eisenlohr LC. Type II alveolar cell MHCII improves respiratory viral disease outcomes while exhibiting limited antigen presentation. Nat Commun. 2021 06 28; 12(1):3993.

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Kelsen JR, Dawany N, Conrad MA, Karakasheva TA, Maurer K, Wei JM, Uman S, Dent MH, Behera R, Bryant LM, Ma X, Moreira L, Chatterji P, Shraim R, Merz A, Mizuno R, Simon LA, Muir AB, Giraudo C, Behrens EM, Whelan KA, Devoto M, Russo PA, Andres SF, Sullivan KE, Hamilton KE. Colonoids From Patients With Pediatric Inflammatory Bowel Disease Exhibit Decreased Growth Associated With Inflammation Severity and Durable Upregulation of Antigen Presentation Genes. Inflamm Bowel Dis. 2021 01 19; 27(2):256-267.

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Levin-Konigsberg R, Mantegazza AR. A guide to measuring phagosomal dynamics. FEBS J. 2021 03; 288(5):1412-1433.

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Forsyth KS, Roy NH, Peauroi E, DeHaven BC, Wold ED, Hersperger AR, Burkhardt JK, Eisenlohr LC. Ectromelia-encoded virulence factor C15 specifically inhibits antigen presentation to CD4+?T cells post peptide loading. PLoS Pathog. 2020 08; 16(8):e1008685.

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Cosma GL, Lobby JL, Fay EJ, Siciliano NA, Langlois RA, Eisenlohr LC. Kinetically distinct processing pathways diversify the CD8+ T cell response to a single viral epitope. Proc Natl Acad Sci U S A. 2020 08 11; 117(32):19399-19407.

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Cho KJ, Ishido S, Eisenlohr LC, Roche PA. Activation of Dendritic Cells Alters the Mechanism of MHC Class II Antigen Presentation to CD4 T Cells. J Immunol. 2020 03 15; 204(6):1621-1629.

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Cosma GL, Eisenlohr LC. Impact of epitope density on CD8+ T cell development and function. Mol Immunol. 2019 09; 113:120-125.

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Forsyth KS, DeHaven B, Mendonca M, Paul S, Sette A, Eisenlohr LC. Poor Antigen Processing of Poxvirus Particles Limits CD4+ T Cell Recognition and Impacts Immunogenicity of the Inactivated Vaccine. J Immunol. 2019 03 01; 202(5):1340-1349.

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