"CD2 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Glycoprotein members of the immunoglobulin superfamily which participate in T-cell adhesion and activation. They are expressed on most peripheral T-lymphocytes, natural killer cells, and thymocytes, and function as co-receptors or accessory molecules in the T-cell receptor complex.
| Descriptor ID |
D018801
|
| MeSH Number(s) |
D23.050.301.264.894.090 D23.101.100.894.090
|
| Concept/Terms |
CD2 Antigens- CD2 Antigens
- CD2 Antigen
- Antigen, CD2
- Antigens, CD2
- T11 Erythrocyte-Binding Glycoprotein
- Erythrocyte-Binding Glycoprotein, T11
- T11 Erythrocyte Binding Glycoprotein
|
Below are MeSH descriptors whose meaning is more general than "CD2 Antigens".
Below are MeSH descriptors whose meaning is more specific than "CD2 Antigens".
This graph shows the total number of publications written about "CD2 Antigens" by people in this website by year, and whether "CD2 Antigens" was a major or minor topic of these publications.
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click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2005 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
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Below are the most recent publications written about "CD2 Antigens" by people in Profiles.
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Tomalka AG, Resto-Garay I, Campbell KS, Popkin DL. In vitro Evidence That Combination Therapy With CD16-Bearing NK-92 Cells and FDA-Approved Alefacept Can Selectively Target the Latent HIV Reservoir in CD4+ CD2hi Memory T Cells. Front Immunol. 2018; 9:2552.
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Grier JT, Forbes LR, Monaco-Shawver L, Oshinsky J, Atkinson TP, Moody C, Pandey R, Campbell KS, Orange JS. Human immunodeficiency-causing mutation defines CD16 in spontaneous NK cell cytotoxicity. J Clin Invest. 2012 Oct; 122(10):3769-80.
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Xu M, Sharma A, Wiest DL, Sen JM. Pre-TCR-induced beta-catenin facilitates traversal through beta-selection. J Immunol. 2009 Jan 15; 182(2):751-8.
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Garthwaite G, Batchelor AM, Goodwin DA, Hewson AK, Leeming K, Ahmed Z, Cuzner ML, Garthwaite J. Pathological implications of iNOS expression in central white matter: an ex vivo study of optic nerves from rats with experimental allergic encephalomyelitis. Eur J Neurosci. 2005 Apr; 21(8):2127-35.
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Zhang Z, Zhang M, Ravetch JV, Goldman C, Waldmann TA. Effective therapy for a murine model of adult T-cell leukemia with the humanized anti-CD2 monoclonal antibody, MEDI-507. Blood. 2003 Jul 01; 102(1):284-8.
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Batuman OA, Ferrero A, Cupp C, Jimenez SA, Khalili K. Differential regulation of transforming growth factor beta-1 gene expression by glucocorticoids in human T and glial cells. J Immunol. 1995 Nov 01; 155(9):4397-405.
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Abraham D, Bou-Gharios G, Tulip G, Sumner H, Olsen I. Regulation of CD2-mediated heterotypic interactions of murine T lymphocytes. Cell Immunol. 1994 Jul; 156(2):342-56.
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Evans CF, Rall GF, Killeen N, Littman D, Oldstone MB. CD2-deficient mice generate virus-specific cytotoxic T lymphocytes upon infection with lymphocytic choriomeningitis virus. J Immunol. 1993 Dec 01; 151(11):6259-64.
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Abraham DJ, Bou-Gharios G, Beauchamp JR, Plater-Zyberk C, Maini RN, Olsen I. Function and regulation of the murine lymphocyte CD2 receptor. J Leukoc Biol. 1991 Apr; 49(4):329-41.