"CD18 Antigens" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cell-surface glycoprotein beta-chains that are non-covalently linked to specific alpha-chains of the CD11 family of leukocyte-adhesion molecules (RECEPTORS, LEUKOCYTE-ADHESION). A defect in the gene encoding CD18 causes LEUKOCYTE-ADHESION DEFICIENCY SYNDROME.
| Descriptor ID |
D018821
|
| MeSH Number(s) |
D12.776.395.550.200.275.750 D12.776.543.550.200.275.750 D12.776.543.750.705.408.200.249 D12.776.543.750.705.408.600.100.750 D12.776.543.750.705.833.249.750 D23.050.301.264.894.118 D23.050.301.350.275.750 D23.101.100.894.118
|
| Concept/Terms |
CD18 Antigens- CD18 Antigens
- p150,95 beta-Subunit
- beta-Subunit, p150,95
- p150,95 beta Subunit
- Integrin beta2
- beta2, Integrin
- beta2 Integrin
- Integrin, beta2
- CD18 Antigen
- Antigens, CD18
|
Below are MeSH descriptors whose meaning is more general than "CD18 Antigens".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Glycoproteins [D12.776.395]
- Membrane Glycoproteins [D12.776.395.550]
- Cell Adhesion Molecules [D12.776.395.550.200]
- Integrin alphaXbeta2 [D12.776.395.550.200.275]
- CD18 Antigens [D12.776.395.550.200.275.750]
- Membrane Proteins [D12.776.543]
- Membrane Glycoproteins [D12.776.543.550]
- Cell Adhesion Molecules [D12.776.543.550.200]
- Integrin alphaXbeta2 [D12.776.543.550.200.275]
- CD18 Antigens [D12.776.543.550.200.275.750]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, Immunologic [D12.776.543.750.705]
- Integrins [D12.776.543.750.705.408]
- Integrin beta Chains [D12.776.543.750.705.408.200]
- CD18 Antigens [D12.776.543.750.705.408.200.249]
- Receptors, Leukocyte-Adhesion [D12.776.543.750.705.408.600]
- Integrin alphaXbeta2 [D12.776.543.750.705.408.600.100]
- CD18 Antigens [D12.776.543.750.705.408.600.100.750]
- Receptors, Complement [D12.776.543.750.705.833]
- Integrin alphaXbeta2 [D12.776.543.750.705.833.249]
- CD18 Antigens [D12.776.543.750.705.833.249.750]
- Biological Factors [D23]
- Antigens [D23.050]
- Antigens, Surface [D23.050.301]
- Antigens, Differentiation [D23.050.301.264]
- Antigens, Differentiation, T-Lymphocyte [D23.050.301.264.894]
- CD18 Antigens [D23.050.301.264.894.118]
- Cell Adhesion Molecules [D23.050.301.350]
- Integrin alphaXbeta2 [D23.050.301.350.275]
- CD18 Antigens [D23.050.301.350.275.750]
- Biomarkers [D23.101]
- Antigens, Differentiation [D23.101.100]
- Antigens, Differentiation, T-Lymphocyte [D23.101.100.894]
- CD18 Antigens [D23.101.100.894.118]
Below are MeSH descriptors whose meaning is more specific than "CD18 Antigens".
This graph shows the total number of publications written about "CD18 Antigens" by people in this website by year, and whether "CD18 Antigens" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 2 | 3 |
| 2013 | 1 | 0 | 1 |
| 2018 | 0 | 1 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "CD18 Antigens" by people in Profiles.
-
Nowatzky J, Manches O, Khan SA, Godefroy E, Bhardwaj N. Modulation of human Th17 cell responses through complement receptor 3 (CD11?b/CD18) ligation on monocyte-derived dendritic cells. J Autoimmun. 2018 08; 92:57-66.
-
Thom SR, Bhopale VM, Milovanova TN, Yang M, Bogush M, Buerk DG. Nitric-oxide synthase-2 linkage to focal adhesion kinase in neutrophils influences enzyme activity and ?2 integrin function. J Biol Chem. 2013 Feb 15; 288(7):4810-8.
-
Thom SR, Bhopale VM, Milovanova TN, Yang M, Bogush M. Thioredoxin reductase linked to cytoskeleton by focal adhesion kinase reverses actin S-nitrosylation and restores neutrophil ?(2) integrin function. J Biol Chem. 2012 Aug 31; 287(36):30346-57.
-
Leal SM, Vareechon C, Cowden S, Cobb BA, Latgé JP, Momany M, Pearlman E. Fungal antioxidant pathways promote survival against neutrophils during infection. J Clin Invest. 2012 Jul; 122(7):2482-98.
-
Thom SR, Milovanova TN, Bogush M, Bhopale VM, Yang M, Bushmann K, Pollock NW, Ljubkovic M, Denoble P, Dujic Z. Microparticle production, neutrophil activation, and intravascular bubbles following open-water SCUBA diving. J Appl Physiol (1985). 2012 Apr; 112(8):1268-78.
-
Thom SR, Bhopale VM, Yang M, Bogush M, Huang S, Milovanova TN. Neutrophil beta2 integrin inhibition by enhanced interactions of vasodilator-stimulated phosphoprotein with S-nitrosylated actin. J Biol Chem. 2011 Sep 16; 286(37):32854-65.
-
Rhee P, Morris J, Durham R, Hauser C, Cipolle M, Wilson R, Luchette F, McSwain N, Miller R. Recombinant humanized monoclonal antibody against CD18 (rhuMAb CD18) in traumatic hemorrhagic shock: results of a phase II clinical trial. Traumatic Shock Group. J Trauma. 2000 Oct; 49(4):611-9; discussion 619-20.