"Phosphotyrosine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An amino acid that occurs in endogenous proteins. Tyrosine phosphorylation and dephosphorylation plays a role in cellular signal transduction and possibly in cell growth control and carcinogenesis.
| Descriptor ID |
D019000
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| MeSH Number(s) |
D12.125.072.050.875.750 D12.125.740.740
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Phosphotyrosine".
Below are MeSH descriptors whose meaning is more specific than "Phosphotyrosine".
This graph shows the total number of publications written about "Phosphotyrosine" by people in this website by year, and whether "Phosphotyrosine" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 0 | 2 | 2 |
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Below are the most recent publications written about "Phosphotyrosine" by people in Profiles.
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Ni M, MacFarlane AW, Toft M, Lowell CA, Campbell KS, Hamerman JA. B-cell adaptor for PI3K (BCAP) negatively regulates Toll-like receptor signaling through activation of PI3K. Proc Natl Acad Sci U S A. 2012 Jan 03; 109(1):267-72.
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Peck AR, Witkiewicz AK, Liu C, Stringer GA, Klimowicz AC, Pequignot E, Freydin B, Tran TH, Yang N, Rosenberg AL, Hooke JA, Kovatich AJ, Nevalainen MT, Shriver CD, Hyslop T, Sauter G, Rimm DL, Magliocco AM, Rui H. Loss of nuclear localized and tyrosine phosphorylated Stat5 in breast cancer predicts poor clinical outcome and increased risk of antiestrogen therapy failure. J Clin Oncol. 2011 Jun 20; 29(18):2448-58.
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Nystr?m A, Shaik ZP, Gullberg D, Krieg T, Eckes B, Zent R, Pozzi A, Iozzo RV. Role of tyrosine phosphatase SHP-1 in the mechanism of endorepellin angiostatic activity. Blood. 2009 Nov 26; 114(23):4897-906.
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Yusa S, Catina TL, Campbell KS. SHP-1- and phosphotyrosine-independent inhibitory signaling by a killer cell Ig-like receptor cytoplasmic domain in human NK cells. J Immunol. 2002 May 15; 168(10):5047-57.
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Takasu MA, Dalva MB, Zigmond RE, Greenberg ME. Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors. Science. 2002 Jan 18; 295(5554):491-5.
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Watterson KR, Johnston E, Chalmers C, Pronin A, Cook SJ, Benovic JL, Palmer TM. Dual regulation of EDG1/S1P(1) receptor phosphorylation and internalization by protein kinase C and G-protein-coupled receptor kinase 2. J Biol Chem. 2002 Feb 22; 277(8):5767-77.
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Morgan JC, Majors JE, Galileo DS. Wild-type and mutant forms of v-src differentially alter neuronal migration and differentiation in vivo. J Neurosci Res. 2000 Jan 15; 59(2):226-37.
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Eischen CM, Dick CJ, Leibson PJ. Tyrosine kinase activation provides an early and requisite signal for Fas-induced apoptosis. J Immunol. 1994 Sep 01; 153(5):1947-54.