Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
"Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A mass spectrometric technique that is used for the analysis of large biomolecules. Analyte molecules are embedded in an excess matrix of small organic molecules that show a high resonant absorption at the laser wavelength used. The matrix absorbs the laser energy, thus inducing a soft disintegration of the sample-matrix mixture into free (gas phase) matrix and analyte molecules and molecular ions. In general, only molecular ions of the analyte molecules are produced, and almost no fragmentation occurs. This makes the method well suited for molecular weight determinations and mixture analysis.
| Descriptor ID |
D019032
|
| MeSH Number(s) |
E05.196.566.755
|
| Concept/Terms |
Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization- Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectrometry, Matrix Assisted Laser Desorption Ionization
- Matrix-Assisted Laser Desorption-Ionization Mass Spectrometry
- Matrix Assisted Laser Desorption Ionization Mass Spectrometry
- MALDI
- Spectroscopy, Mass, Matrix-Assisted Laser Desorption-Ionization
- MS-MALD
- MALD-MS
- MALDI-MS
- MALDI MS
- Laser Desorption-Ionization Mass Spectrometry, Matrix-Assisted
- Laser Desorption Ionization Mass Spectrometry, Matrix Assisted
- Mass Spectroscopy, Matrix-Assisted Laser Desorption-Ionization
- Mass Spectroscopy, Matrix Assisted Laser Desorption Ionization
|
Below are MeSH descriptors whose meaning is more general than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
Below are MeSH descriptors whose meaning is more specific than "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization".
This graph shows the total number of publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in this website by year, and whether "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 3 | 3 |
| 2003 | 1 | 5 | 6 |
| 2004 | 0 | 4 | 4 |
| 2005 | 0 | 6 | 6 |
| 2006 | 0 | 5 | 5 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 4 | 4 |
| 2009 | 0 | 2 | 2 |
| 2010 | 0 | 4 | 4 |
| 2011 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
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Below are the most recent publications written about "Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization" by people in Profiles.
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Jin S, Merchant ML, Ritzenthaler JD, McLeish KR, Lederer ED, Torres-Gonzalez E, Fraig M, Barati MT, Lentsch AB, Roman J, Klein JB, Rane MJ. Baclofen, a GABABR agonist, ameliorates immune-complex mediated acute lung injury by modulating pro-inflammatory mediators. PLoS One. 2015; 10(4):e0121637.
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Roberts AL. Identification of Staphylococcus epidermidis in the clinical microbiology laboratory by molecular methods. Methods Mol Biol. 2014; 1106:33-53.
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Buskirk AD, Templeton SP, Nayak AP, Hettick JM, Law BF, Green BJ, Beezhold DH. Pulmonary immune responses to Aspergillus fumigatus in an immunocompetent mouse model of repeated exposures. J Immunotoxicol. 2014 Apr-Jun; 11(2):180-9.
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Top A, Roberts CJ, Kiick KL. Conformational and aggregation properties of a PEGylated alanine-rich polypeptide. Biomacromolecules. 2011 Jun 13; 12(6):2184-92.
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Choi YS, Choe LH, Lee KH. Recent cerebrospinal fluid biomarker studies of Alzheimer's disease. Expert Rev Proteomics. 2010 Dec; 7(6):919-29.
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Del Galdo F, Shaw MA, Jimenez SA. Proteomic analysis identification of a pattern of shared alterations in the secretome of dermal fibroblasts from systemic sclerosis and nephrogenic systemic fibrosis. Am J Pathol. 2010 Oct; 177(4):1638-46.
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Nayak AP, Blachere FM, Hettick JM, Lukomski S, Schmechel D, Beezhold DH. Characterization of recombinant terrelysin, a hemolysin of Aspergillus terreus. Mycopathologia. 2011 Jan; 171(1):23-34.
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Chung CH, Seeley EH, Roder H, Grigorieva J, Tsypin M, Roder J, Burtness BA, Argiris A, Forastiere AA, Gilbert J, Murphy B, Caprioli RM, Carbone DP, Cohen EE. Detection of tumor epidermal growth factor receptor pathway dependence by serum mass spectrometry in cancer patients. Cancer Epidemiol Biomarkers Prev. 2010 Feb; 19(2):358-65.
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Zhou J, Trock B, Tsangaris TN, Friedman NB, Shapiro D, Brotzman M, Chan-Li Y, Chan DW, Li J. A unique proteolytic fragment of alpha1-antitrypsin is elevated in ductal fluid of breast cancer patient. Breast Cancer Res Treat. 2010 Aug; 123(1):73-86.
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Lin Y, Buckhaults PJ, Lee JR, Xiong H, Farrell C, Podolsky RH, Schade RR, Dynan WS. Association of the actin-binding protein transgelin with lymph node metastasis in human colorectal cancer. Neoplasia. 2009 Sep; 11(9):864-73.