Brain-Derived Neurotrophic Factor

"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)

Descriptor ID	D019208
MeSH Number(s)	D12.644.276.860.100 D12.776.467.860.100 D12.776.631.600.100 D23.529.850.100
Concept/Terms	Brain-Derived Neurotrophic Factor Brain-Derived Neurotrophic Factor Brain Derived Neurotrophic Factor Factor, Brain-Derived Neurotrophic Neurotrophic Factor, Brain-Derived BDNF

Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Nerve Growth Factors [D12.644.276.860]
Brain-Derived Neurotrophic Factor [D12.644.276.860.100]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Nerve Growth Factors [D12.776.467.860]
Brain-Derived Neurotrophic Factor [D12.776.467.860.100]
Nerve Tissue Proteins [D12.776.631]
Nerve Growth Factors [D12.776.631.600]
Brain-Derived Neurotrophic Factor [D12.776.631.600.100]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Nerve Growth Factors [D23.529.850]
Brain-Derived Neurotrophic Factor [D23.529.850.100]

Below are MeSH descriptors whose meaning is related to "Brain-Derived Neurotrophic Factor".

Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in this website by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.

Bar chart showing 18 publications over 13 distinct years, with a maximum of 2 publications in 2003 and 2005 and 2009 and 2011 and 2012

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2003	0	2	2
2005	1	1	2
2007	1	0	1
2009	2	0	2
2010	0	1	1
2011	1	1	2
2012	2	0	2
2013	0	1	1
2016	0	1	1
2017	1	0	1
2020	1	0	1
2021	1	0	1

Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles.

Singh A, Rattan S. BDNF rescues aging-associated internal anal sphincter dysfunction. Am J Physiol Gastrointest Liver Physiol. 2021 07 01; 321(1):G87-G97.

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Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E, Beers MF, Weitzman MD, Morrisey EE, Worthen GS. STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. 2020 10; 22(10):1197-1210.

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Pillai A, Schooler NR, Peter D, Looney SW, Goff DC, Kopelowicz A, Lauriello J, Manschreck T, Mendelowitz A, Miller DD, Severe JB, Wilson DR, Ames D, Bustillo J, Kane JM, Buckley PF. Predicting relapse in schizophrenia: Is BDNF a plausible biological marker? Schizophr Res. 2018 03; 193:263-268.

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Sun MK, Hongpaisan J, Alkon DL. Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice. J Pharmacol Exp Ther. 2016 May; 357(2):300-10.

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Hongpaisan J, Xu C, Sen A, Nelson TJ, Alkon DL. PKC activation during training restores mushroom spine synapses and memory in the aged rat. Neurobiol Dis. 2013 Jul; 55:44-62.

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Gerecke KM, Jiao Y, Pagala V, Smeyne RJ. Exercise does not protect against MPTP-induced neurotoxicity in BDNF haploinsufficient mice. PLoS One. 2012; 7(8):e43250.

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Nath S, Bachani M, Harshavardhana D, Steiner JP. Catechins protect neurons against mitochondrial toxins and HIV proteins via activation of the BDNF pathway. J Neurovirol. 2012 Dec; 18(6):445-55.

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Meeker RB, Poulton W, Markovic-Plese S, Hall C, Robertson K. Protein changes in CSF of HIV-infected patients: evidence for loss of neuroprotection. J Neurovirol. 2011 Jun; 17(3):258-73.

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Hongpaisan J, Sun MK, Alkon DL. PKC e activation prevents synaptic loss, Aß elevation, and cognitive deficits in Alzheimer's disease transgenic mice. J Neurosci. 2011 Jan 12; 31(2):630-43.

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Beyer CE, Dwyer JM, Piesla MJ, Platt BJ, Shen R, Rahman Z, Chan K, Manners MT, Samad TA, Kennedy JD, Bingham B, Whiteside GT. Depression-like phenotype following chronic CB1 receptor antagonism. Neurobiol Dis. 2010 Aug; 39(2):148-55.

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