Brain-Derived Neurotrophic Factor

"Brain-Derived Neurotrophic Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A member of the nerve growth factor family of trophic factors. In the brain BDNF has a trophic action on retinal, cholinergic, and dopaminergic neurons, and in the peripheral nervous system it acts on both motor and sensory neurons. (From Kendrew, The Encyclopedia of Molecular Biology, 1994)

Descriptor ID	D019208
MeSH Number(s)	D12.644.276.860.100 D12.776.467.860.100 D12.776.631.600.100 D23.529.850.100
Concept/Terms	Brain-Derived Neurotrophic Factor Brain-Derived Neurotrophic Factor Brain Derived Neurotrophic Factor Factor, Brain-Derived Neurotrophic Neurotrophic Factor, Brain-Derived BDNF

Below are MeSH descriptors whose meaning is more general than "Brain-Derived Neurotrophic Factor".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Nerve Growth Factors [D12.644.276.860]
Brain-Derived Neurotrophic Factor [D12.644.276.860.100]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Nerve Growth Factors [D12.776.467.860]
Brain-Derived Neurotrophic Factor [D12.776.467.860.100]
Nerve Tissue Proteins [D12.776.631]
Nerve Growth Factors [D12.776.631.600]
Brain-Derived Neurotrophic Factor [D12.776.631.600.100]
Biological Factors [D23]
Intercellular Signaling Peptides and Proteins [D23.529]
Nerve Growth Factors [D23.529.850]
Brain-Derived Neurotrophic Factor [D23.529.850.100]

Below are MeSH descriptors whose meaning is related to "Brain-Derived Neurotrophic Factor".

Below are MeSH descriptors whose meaning is more specific than "Brain-Derived Neurotrophic Factor".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Brain-Derived Neurotrophic Factor" by people in this website by year, and whether "Brain-Derived Neurotrophic Factor" was a major or minor topic of these publications.

Bar chart showing 27 publications over 19 distinct years, with a maximum of 2 publications in 2003 and 2005 and 2006 and 2007 and 2009 and 2011 and 2012 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2001	0	1	1
2003	0	2	2
2004	1	0	1
2005	1	1	2
2006	0	2	2
2007	1	1	2
2009	2	0	2
2010	0	1	1
2011	1	1	2
2012	2	0	2
2013	0	1	1
2016	0	1	1
2017	1	0	1
2018	1	0	1
2019	1	0	1
2020	1	1	2
2021	1	0	1
2022	0	1	1
2023	0	1	1

Below are the most recent publications written about "Brain-Derived Neurotrophic Factor" by people in Profiles.

Vyas CM, Mischoulon D, Chang G, Reynolds CF, Cook NR, Weinberg A, Copeland T, Bubes V, Bradwin G, Lee IM, Buring JE, Mora S, Rifai N, Manson JE, Okereke OI. Relation of serum BDNF to major depression and exploration of mechanistic roles of serum BDNF in a study of vitamin D3 and omega-3 supplements for late-life depression prevention. J Psychiatr Res. 2023 Jul; 163:357-364.

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Dong Z, Zhan T, Sun H, Wang J, Duan G, Zhang Y, Chen Y, Huang Y, Xu S. Astrocytic ERK/STAT1 Signaling Contributes to Maintenance of Stress-Related Visceral Hypersensitivity in Rats. J Pain. 2022 11; 23(11):1973-1988.

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Singh A, Rattan S. BDNF rescues aging-associated internal anal sphincter dysfunction. Am J Physiol Gastrointest Liver Physiol. 2021 07 01; 321(1):G87-G97.

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Paris AJ, Hayer KE, Oved JH, Avgousti DC, Toulmin SA, Zepp JA, Zacharias WJ, Katzen JB, Basil MC, Kremp MM, Slamowitz AR, Jayachandran S, Sivakumar A, Dai N, Wang P, Frank DB, Eisenlohr LC, Cantu E, Beers MF, Weitzman MD, Morrisey EE, Worthen GS. STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. 2020 10; 22(10):1197-1210.

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Asadi-Pooya AA. Rediscovery of Rue for the treatment of epilepsy. Epilepsy Res. 2020 11; 167:106434.

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Shrestha S, Phay M, Kim HH, Pouladvand P, Lee SJ, Yoo S. Differential regulation of brain-derived neurotrophic factor (BDNF) expression in sensory neuron axons by miRNA-206. FEBS Open Bio. 2019 02; 9(2):374-383.

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Cotto B, Li H, Tuma RF, Ward SJ, Langford D. Cocaine-mediated activation of microglia and microglial MeCP2 and BDNF production. Neurobiol Dis. 2018 09; 117:28-41.

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Pillai A, Schooler NR, Peter D, Looney SW, Goff DC, Kopelowicz A, Lauriello J, Manschreck T, Mendelowitz A, Miller DD, Severe JB, Wilson DR, Ames D, Bustillo J, Kane JM, Buckley PF. Predicting relapse in schizophrenia: Is BDNF a plausible biological marker? Schizophr Res. 2018 03; 193:263-268.

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Sun MK, Hongpaisan J, Alkon DL. Rescue of Synaptic Phenotypes and Spatial Memory in Young Fragile X Mice. J Pharmacol Exp Ther. 2016 May; 357(2):300-10.

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Hongpaisan J, Xu C, Sen A, Nelson TJ, Alkon DL. PKC activation during training restores mushroom spine synapses and memory in the aged rat. Neurobiol Dis. 2013 Jul; 55:44-62.

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