"Receptors, CCR5" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
CCR receptors with specificity for CHEMOKINE CCL3; CHEMOKINE CCL4; and CHEMOKINE CCL5. They are expressed at high levels in T-LYMPHOCYTES; B-LYMPHOCYTES; MACROPHAGES; MAST CELLS; and NK CELLS. The CCR5 receptor is used by the HUMAN IMMUNODEFICIENCY VIRUS to infect cells.
| Descriptor ID |
D019713
|
| MeSH Number(s) |
D12.776.543.750.695.160.150.500 D12.776.543.750.705.852.125.150.500 D12.776.543.750.830.700.605
|
| Concept/Terms |
Receptors, CCR5- Receptors, CCR5
- CC-CKR5
- CCR5 Receptor
- Receptor, CCR5
- CCR5 Receptors
- Antigens, CD195
- CKR5 Receptors
- Receptors, CKR5
- CD195 Antigens
- CC Chemokine Receptor 5
|
Below are MeSH descriptors whose meaning is more general than "Receptors, CCR5".
- Chemicals and Drugs [D]
- Amino Acids, Peptides, and Proteins [D12]
- Proteins [D12.776]
- Membrane Proteins [D12.776.543]
- Receptors, Cell Surface [D12.776.543.750]
- Receptors, G-Protein-Coupled [D12.776.543.750.695]
- Receptors, Chemokine [D12.776.543.750.695.160]
- Receptors, CCR [D12.776.543.750.695.160.150]
- Receptors, CCR5 [D12.776.543.750.695.160.150.500]
- Receptors, Immunologic [D12.776.543.750.705]
- Receptors, Cytokine [D12.776.543.750.705.852]
- Receptors, Chemokine [D12.776.543.750.705.852.125]
- Receptors, CCR [D12.776.543.750.705.852.125.150]
- Receptors, CCR5 [D12.776.543.750.705.852.125.150.500]
- Receptors, Virus [D12.776.543.750.830]
- Receptors, HIV [D12.776.543.750.830.700]
- Receptors, CCR5 [D12.776.543.750.830.700.605]
Below are MeSH descriptors whose meaning is more specific than "Receptors, CCR5".
This graph shows the total number of publications written about "Receptors, CCR5" by people in this website by year, and whether "Receptors, CCR5" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 2 | 0 | 2 |
| 2005 | 1 | 0 | 1 |
| 2006 | 1 | 1 | 2 |
| 2009 | 1 | 2 | 3 |
| 2010 | 1 | 1 | 2 |
| 2011 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2019 | 0 | 1 | 1 |
| 2022 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Receptors, CCR5" by people in Profiles.
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Raghavakaimal A, Cristofanilli M, Tang CM, Alpaugh RK, Gardner KP, Chumsri S, Adams DL. CCR5 activation and endocytosis in circulating tumor-derived cells isolated from the blood of breast cancer patients provide information about clinical outcome. Breast Cancer Res. 2022 May 23; 24(1):35.
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Gomez-Ospina N, Scharenberg SG, Mostrel N, Bak RO, Mantri S, Quadros RM, Gurumurthy CB, Lee C, Bao G, Suarez CJ, Khan S, Sawamoto K, Tomatsu S, Raj N, Attardi LD, Aurelian L, Porteus MH. Human genome-edited hematopoietic stem cells phenotypically correct Mucopolysaccharidosis type I. Nat Commun. 2019 09 06; 10(1):4045.
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Velasco-Velázquez M, Jiao X, De La Fuente M, Pestell TG, Ertel A, Lisanti MP, Pestell RG. CCR5 antagonist blocks metastasis of basal breast cancer cells. Cancer Res. 2012 Aug 1; 72(15):3839-50.
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Marusich E, Louboutin JP, Chekmasova AA, Strayer DS. Lymphocyte adhesion to CCR5 ligands is reduced by anti-CCR5 gene delivery. J Neurol Sci. 2011 Sep 15; 308(1-2):25-7.
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Louboutin JP, Chekmasova A, Marusich E, Agrawal L, Strayer DS. Role of CCR5 and its ligands in the control of vascular inflammation and leukocyte recruitment required for acute excitotoxic seizure induction and neural damage. FASEB J. 2011 Feb; 25(2):737-53.
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Feng P, Wang H, Feldman RS, Pribitkin EA, Breslin PA. The T cells in peripheral taste tissue of healthy human adults: predominant memory T cells and Th-1 cells. Chem Senses. 2010 Jul; 35(6):501-9.
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Kandavelou K, Ramalingam S, London V, Mani M, Wu J, Alexeev V, Civin CI, Chandrasegaran S. Targeted manipulation of mammalian genomes using designed zinc finger nucleases. Biochem Biophys Res Commun. 2009 Oct 9; 388(1):56-61.
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Knieke K, Hoff H, Maszyna F, Kolar P, Schrage A, Hamann A, Debes GF, Brunner-Weinzierl MC. CD152 (CTLA-4) determines CD4 T cell migration in vitro and in vivo. PLoS One. 2009 May 27; 4(5):e5702.
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Agrawal L, Maxwell CR, Peters PJ, Clapham PR, Liu SM, Mackay CR, Strayer DS. Complexity in human immunodeficiency virus type 1 (HIV-1) co-receptor usage: roles of CCR3 and CCR5 in HIV-1 infection of monocyte-derived macrophages and brain microglia. J Gen Virol. 2009 Mar; 90(Pt 3):710-22.
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Sundaravaradan V, Saxena SK, Ramakrishnan R, Yedavalli VR, Harris DT, Ahmad N. Differential HIV-1 replication in neonatal and adult blood mononuclear cells is influenced at the level of HIV-1 gene expression. Proc Natl Acad Sci U S A. 2006 Aug 01; 103(31):11701-6.