"cdc25 Phosphatases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A subclass of dual specificity phosphatases that play a role in the progression of the CELL CYCLE. They dephosphorylate and activate CYCLIN-DEPENDENT KINASES.
| Descriptor ID |
D020687
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| MeSH Number(s) |
D08.811.277.352.650.625.225.100 D08.811.277.352.650.775.250.100 D08.811.641.755.100 D12.644.360.268.100 D12.776.167.100 D12.776.476.268.100
|
| Concept/Terms |
cdc25 Phosphatases- cdc25 Phosphatases
- Phosphatases, cdc25
- cdc25 Phosphatase
- Phosphatase, cdc25
cdc25B Phosphatase- cdc25B Phosphatase
- Phosphatase, cdc25B
- M-Phase Inducer Phosphatase 2
- M Phase Inducer Phosphatase 2
- Dual Specificity Phosphatase Cdc25B
- Cell Division Cycle 25B protein
cdc25C Phosphatase- cdc25C Phosphatase
- Phosphatase, cdc25C
- Dual Specificity Phosphatase Cdc25C
- M-Phase Inducer Phosphatase 3
- M Phase Inducer Phosphatase 3
cdc25A Phosphatase- cdc25A Phosphatase
- Phosphatase, cdc25A
- Dual Specificity Phosphatase Cdc25A
- M-Phase Inducer Phosphatase 1
- M Phase Inducer Phosphatase 1
|
Below are MeSH descriptors whose meaning is more general than "cdc25 Phosphatases".
Below are MeSH descriptors whose meaning is more specific than "cdc25 Phosphatases".
This graph shows the total number of publications written about "cdc25 Phosphatases" by people in this website by year, and whether "cdc25 Phosphatases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 2 | 0 | 2 |
| 2000 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2007 | 2 | 0 | 2 |
| 2014 | 1 | 0 | 1 |
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Below are the most recent publications written about "cdc25 Phosphatases" by people in Profiles.
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Riemer A, Dobrynin G, Dressler A, Bremer S, Soni A, Iliakis G, Meyer H. The p97-Ufd1-Npl4 ATPase complex ensures robustness of the G2/M checkpoint by facilitating CDC25A degradation. Cell Cycle. 2014; 13(6):919-27.
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Vecchione A, Baldassarre G, Ishii H, Nicoloso MS, Belletti B, Petrocca F, Zanesi N, Fong LY, Battista S, Guarnieri D, Baffa R, Alder H, Farber JL, Donovan PJ, Croce CM. Fez1/Lzts1 absence impairs Cdk1/Cdc25C interaction during mitosis and predisposes mice to cancer development. Cancer Cell. 2007 Mar; 11(3):275-89.
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Ray D, Terao Y, Fuhrken PG, Ma ZQ, DeMayo FJ, Christov K, Heerema NA, Franks R, Tsai SY, Papoutsakis ET, Kiyokawa H. Deregulated CDC25A expression promotes mammary tumorigenesis with genomic instability. Cancer Res. 2007 Feb 1; 67(3):984-91.
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Ujiki MB, Ding XZ, Salabat MR, Bentrem DJ, Golkar L, Milam B, Talamonti MS, Bell RH, Iwamura T, Adrian TE. Apigenin inhibits pancreatic cancer cell proliferation through G2/M cell cycle arrest. Mol Cancer. 2006 Dec 29; 5:76.
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Bouzahzah B, Fu M, Iavarone A, Factor VM, Thorgeirsson SS, Pestell RG. Transforming growth factor-beta1 recruits histone deacetylase 1 to a p130 repressor complex in transgenic mice in vivo. Cancer Res. 2000 Aug 15; 60(16):4531-7.
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Bergnes G, Gilliam CL, Boisclair MD, Blanchard JL, Blake KV, Epstein DM, Pal K. Generation of an Ugi library of phosphate mimic-containing compounds and identification of novel dual specific phosphatase inhibitors. Bioorg Med Chem Lett. 1999 Oct 04; 9(19):2849-54.
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Blanchard JL, Epstein DM, Boisclair MD, Rudolph J, Pal K. Dysidiolide and related gamma-hydroxy butenolide compounds as inhibitors of the protein tyrosine phosphatase, CDC25. Bioorg Med Chem Lett. 1999 Sep 06; 9(17):2537-8.