rhoA GTP-Binding Protein

"rhoA GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A RHO GTP-BINDING PROTEIN involved in regulating signal transduction pathways that control assembly of focal adhesions and actin stress fibers. This enzyme was formerly listed as EC 3.6.1.47.

Descriptor ID	D020742
MeSH Number(s)	D08.811.277.040.330.300.400.700.200 D12.644.360.525.700.200 D12.776.157.325.515.700.200 D12.776.476.525.700.200
Concept/Terms	rhoA GTP-Binding Protein rhoA GTP-Binding Protein GTP-Binding Protein, rhoA rhoA GTP Binding Protein rhoA P21 Protein rho12 Protein ARHA GTP-Binding Protein ARHA GTP Binding Protein GTP-Binding Protein, ARHA rhoA Protein Ras Homolog Family Member A rho12 GTP-Binding Protein GTP-Binding Protein, rho12 rho12 GTP Binding Protein V14rho V14rho V14rhoA

Below are MeSH descriptors whose meaning is more general than "rhoA GTP-Binding Protein".

Chemicals and Drugs [D]
Enzymes and Coenzymes [D08]
Enzymes [D08.811]
Hydrolases [D08.811.277]
Acid Anhydride Hydrolases [D08.811.277.040]
GTP Phosphohydrolases [D08.811.277.040.330]
GTP-Binding Proteins [D08.811.277.040.330.300]
Monomeric GTP-Binding Proteins [D08.811.277.040.330.300.400]
rho GTP-Binding Proteins [D08.811.277.040.330.300.400.700]
rhoA GTP-Binding Protein [D08.811.277.040.330.300.400.700.200]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intracellular Signaling Peptides and Proteins [D12.644.360]
Monomeric GTP-Binding Proteins [D12.644.360.525]
rho GTP-Binding Proteins [D12.644.360.525.700]
rhoA GTP-Binding Protein [D12.644.360.525.700.200]
Proteins [D12.776]
Carrier Proteins [D12.776.157]
GTP-Binding Proteins [D12.776.157.325]
Monomeric GTP-Binding Proteins [D12.776.157.325.515]
rho GTP-Binding Proteins [D12.776.157.325.515.700]
rhoA GTP-Binding Protein [D12.776.157.325.515.700.200]
Intracellular Signaling Peptides and Proteins [D12.776.476]
Monomeric GTP-Binding Proteins [D12.776.476.525]
rho GTP-Binding Proteins [D12.776.476.525.700]
rhoA GTP-Binding Protein [D12.776.476.525.700.200]

Below are MeSH descriptors whose meaning is related to "rhoA GTP-Binding Protein".

Below are MeSH descriptors whose meaning is more specific than "rhoA GTP-Binding Protein".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "rhoA GTP-Binding Protein" by people in this website by year, and whether "rhoA GTP-Binding Protein" was a major or minor topic of these publications.

Bar chart showing 55 publications over 22 distinct years, with a maximum of 6 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	0	1	1
1999	0	1	1
2001	0	2	2
2002	1	0	1
2003	3	2	5
2004	1	1	2
2005	2	0	2
2006	0	2	2
2007	2	0	2
2008	2	4	6
2009	1	2	3
2010	3	1	4
2011	2	3	5
2012	1	1	2
2013	2	3	5
2014	1	0	1
2015	0	1	1
2016	1	3	4
2017	2	1	3
2018	0	1	1
2021	1	0	1
2024	0	1	1

Below are the most recent publications written about "rhoA GTP-Binding Protein" by people in Profiles.

Conaway S, Huang W, Hernandez-Lara MA, Kane MA, Penn RB, Deshpande DA. Molecular mechanism of bitter taste receptor agonist-mediated relaxation of airway smooth muscle. FASEB J. 2024 Jul 31; 38(14):e23842.

View in: PubMed
Haines A, Wesolowski J, Ryan NM, Monteiro-Br?s T, Paumet F. Cross Talk between ARF1 and RhoA Coordinates the Formation of Cytoskeletal Scaffolds during Chlamydia Infection. mBio. 2021 12 21; 12(6):e0239721.

View in: PubMed
Tourdot BE, Stoveken H, Trumbo D, Yeung J, Kanthi Y, Edelstein LC, Bray PF, Tall GG, Holinstat M. Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics. Arterioscler Thromb Vasc Biol. 2018 07; 38(7):1632-1643.

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Yoo EJ, Cao G, Koziol-White CJ, Ojiaku CA, Sunder K, Jude JA, Michael JV, Lam H, Pushkarsky I, Damoiseaux R, Di Carlo D, Ahn K, An SS, Penn RB, Panettieri RA. Ga12 facilitates shortening in human airway smooth muscle by modulating phosphoinositide 3-kinase-mediated activation in a RhoA-dependent manner. Br J Pharmacol. 2017 Dec; 174(23):4383-4395.

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Park J, Yang J, Wenzel AT, Ramachandran A, Lee WJ, Daniels JC, Kim J, Martinez-Escala E, Amankulor N, Pro B, Guitart J, Mendillo ML, Savas JN, Boggon TJ, Choi J. Genomic analysis of 220 CTCLs identifies a novel recurrent gain-of-function alteration in RLTPR (p.Q575E). Blood. 2017 09 21; 130(12):1430-1440.

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Horowitz A, Yang J, Cai J, Iacovitti L. The versatility of RhoA activities in neural differentiation. Small GTPases. 2019 01; 10(1):26-32.

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Rattan S. Ca2+/calmodulin/MLCK pathway initiates, and RhoA/ROCK maintains, the internal anal sphincter smooth muscle tone. Am J Physiol Gastrointest Liver Physiol. 2017 01 01; 312(1):G63-G66.

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Bon E, Driffort V, Gradek F, Martinez-Caceres C, Anchelin M, Pelegrin P, Cayuela ML, Marionneau-Lambot S, Oullier T, Guibon R, Fromont G, Gutierrez-Pajares JL, Domingo I, Piver E, Moreau A, Burlaud-Gaillard J, Frank PG, Chevalier S, Besson P, Roger S. SCN4B acts as a metastasis-suppressor gene preventing hyperactivation of cell migration in breast cancer. Nat Commun. 2016 12 05; 7:13648.

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Weber MM, Faris R, van Schaik EJ, McLachlan JT, Wright WU, Tellez A, Roman VA, Rowin K, Case ED, Luo ZQ, Samuel JE. The Type IV Secretion System Effector Protein CirA Stimulates the GTPase Activity of RhoA and Is Required for Virulence in a Mouse Model of Coxiella burnetii Infection. Infect Immun. 2016 09; 84(9):2524-33.

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Yang J, Wu C, Stefanescu I, Jakobsson L, Chervoneva I, Horowitz A. RhoA inhibits neural differentiation in murine stem cells through multiple mechanisms. Sci Signal. 2016 07 26; 9(438):ra76.

View in: PubMed

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