cdc42 GTP-Binding Protein
"cdc42 GTP-Binding Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the Rho family of MONOMERIC GTP-BINDING PROTEINS. It is associated with a diverse array of cellular functions including cytoskeletal changes, filopodia formation and transport through the GOLGI APPARATUS. This enzyme was formerly listed as EC 3.6.1.47.
| Descriptor ID |
D020764
|
| MeSH Number(s) |
D08.811.277.040.330.300.400.700.050 D12.644.360.525.700.050 D12.776.157.325.515.700.050 D12.776.476.525.700.050
|
| Concept/Terms |
cdc42 GTP-Binding Protein- cdc42 GTP-Binding Protein
- GTP-Binding Protein, cdc42
- cdc42 GTP Binding Protein
- p21 cdc42
- cdc42, p21
- cdc42 Protein
- G25K Protein
|
Below are MeSH descriptors whose meaning is more general than "cdc42 GTP-Binding Protein".
Below are MeSH descriptors whose meaning is more specific than "cdc42 GTP-Binding Protein".
This graph shows the total number of publications written about "cdc42 GTP-Binding Protein" by people in this website by year, and whether "cdc42 GTP-Binding Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 2 | 2 |
| 2003 | 1 | 0 | 1 |
| 2004 | 3 | 0 | 3 |
| 2005 | 0 | 1 | 1 |
| 2006 | 1 | 2 | 3 |
| 2007 | 1 | 0 | 1 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 0 | 1 |
| 2013 | 1 | 0 | 1 |
| 2021 | 2 | 0 | 2 |
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Below are the most recent publications written about "cdc42 GTP-Binding Protein" by people in Profiles.
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Duan X, Perveen R, Dandamudi A, Adili R, Johnson J, Funk K, Berryman M, Davis AK, Holinstat M, Zheng Y, Akbar H. Pharmacologic targeting of Cdc42 GTPase by a small molecule Cdc42 activity-specific inhibitor prevents platelet activation and thrombosis. Sci Rep. 2021 06 23; 11(1):13170.
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Nichols KE, Giraudo CG. RHOG: Rac1-ing up another HLH gene. Blood. 2021 04 15; 137(15):1990-1991.
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Simionescu-Bankston A, Leoni G, Wang Y, Pham PP, Ramalingam A, DuHadaway JB, Faundez V, Nusrat A, Prendergast GC, Pavlath GK. The N-BAR domain protein, Bin3, regulates Rac1- and Cdc42-dependent processes in myogenesis. Dev Biol. 2013 Oct 01; 382(1):160-71.
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Carito V, Bonuccelli G, Martinez-Outschoorn UE, Whitaker-Menezes D, Caroleo MC, Cione E, Howell A, Pestell RG, Lisanti MP, Sotgia F. Metabolic remodeling of the tumor microenvironment: migration stimulating factor (MSF) reprograms myofibroblasts toward lactate production, fueling anabolic tumor growth. Cell Cycle. 2012 Sep 15; 11(18):3403-14.
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Huang M, Satchell L, Duhadaway JB, Prendergast GC, Laury-Kleintop LD. RhoB links PDGF signaling to cell migration by coordinating activation and localization of Cdc42 and Rac. J Cell Biochem. 2011 Jun; 112(6):1572-84.
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Pavlov TS, Chahdi A, Ilatovskaya DV, Levchenko V, Vandewalle A, Pochynyuk O, Sorokin A, Staruschenko A. Endothelin-1 inhibits the epithelial Na+ channel through betaPix/14-3-3/Nedd4-2. J Am Soc Nephrol. 2010 May; 21(5):833-43.
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Chahdi A, Sorokin A. The role of beta(1)Pix/caveolin-1 interaction in endothelin signaling through Galpha subunits. Biochem Biophys Res Commun. 2010 Jan 15; 391(3):1330-5.
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Qian Y, Luo J, Leonard SS, Harris GK, Millecchia L, Flynn DC, Shi X. Hydrogen peroxide formation and actin filament reorganization by Cdc42 are essential for ethanol-induced in vitro angiogenesis. Nihon Arukoru Yakubutsu Igakkai Zasshi. 2007 Dec; 42(6):605-9.
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Chahdi A, Sorokin A. Endothelin 1 stimulates beta1Pix-dependent activation of Cdc42 through the G(salpha) pathway. Exp Biol Med (Maywood). 2006 Jun; 231(6):761-5.
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Yao H, Dashner EJ, van Golen CM, van Golen KL. RhoC GTPase is required for PC-3 prostate cancer cell invasion but not motility. Oncogene. 2006 Apr 13; 25(16):2285-96.