"Calnexin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A lectin found in ENDOPLASMIC RETICULUM membranes that binds to specific N-linked OLIGOSACCHARIDES found on newly synthesized proteins. It may play role in PROTEIN FOLDING or retention and degradation of misfolded proteins in the endoplasmic reticulum.
| Descriptor ID |
D037281
|
| MeSH Number(s) |
D12.644.360.372.311 D12.776.157.125.412.311 D12.776.476.387.311 D12.776.503.295 D12.776.543.162
|
| Concept/Terms |
Calnexin- Calnexin
- Phosphoprotein pp90
- pp90, Phosphoprotein
- IP90 Protein
- Integral Membrane Protein IP90
|
Below are MeSH descriptors whose meaning is more general than "Calnexin".
Below are MeSH descriptors whose meaning is more specific than "Calnexin".
This graph shows the total number of publications written about "Calnexin" by people in this website by year, and whether "Calnexin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
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Below are the most recent publications written about "Calnexin" by people in Profiles.
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Joseph SK, Boehning D, Bokkala S, Watkins R, Widjaja J. Biosynthesis of inositol trisphosphate receptors: selective association with the molecular chaperone calnexin. Biochem J. 1999 Aug 15; 342 ( Pt 1):153-61.
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Wiest DL, Bhandoola A, Punt J, Kreibich G, McKean D, Singer A. Incomplete endoplasmic reticulum (ER) retention in immature thymocytes as revealed by surface expression of "ER-resident" molecular chaperones. Proc Natl Acad Sci U S A. 1997 Mar 04; 94(5):1884-9.
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Wiest DL, Burgess WH, McKean D, Kearse KP, Singer A. The molecular chaperone calnexin is expressed on the surface of immature thymocytes in association with clonotype-independent CD3 complexes. EMBO J. 1995 Jul 17; 14(14):3425-33.