Interferon Regulatory Factor-1
"Interferon Regulatory Factor-1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An interferon regulatory factor that binds upstream TRANSCRIPTIONAL REGULATORY ELEMENTS in the GENES for INTERFERON-ALPHA and INTERFERON-BETA. It functions as a transcriptional activator for the INTERFERON TYPE I genes.
Descriptor ID |
D050856
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MeSH Number(s) |
D12.644.360.024.302.124 D12.776.157.057.050.124 D12.776.260.108.374 D12.776.260.504.124 D12.776.476.024.385.124 D12.776.930.127.374 D12.776.930.332.124
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Concept/Terms |
Interferon Regulatory Factor-1- Interferon Regulatory Factor-1
- Interferon Regulatory Factor 1
- IRF-1 Protein
- IRF 1 Protein
- IREBF1 Transcription Factor
- Transcription Factor, IREBF1
- IREBF1 Protein
- IRF-1 Transcription Factor
- Factor, IRF-1 Transcription
- IRF 1 Transcription Factor
- Transcription Factor, IRF-1
- ISGF1 Transcription Factor
- Factor, ISGF1 Transcription
- Transcription Factor, ISGF1
- Interferon-Stimulated Gene Factor 1
- Interferon Stimulated Gene Factor 1
- MyD32 Protein
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Below are MeSH descriptors whose meaning is more general than "Interferon Regulatory Factor-1".
Below are MeSH descriptors whose meaning is more specific than "Interferon Regulatory Factor-1".
This graph shows the total number of publications written about "Interferon Regulatory Factor-1" by people in this website by year, and whether "Interferon Regulatory Factor-1" was a major or minor topic of these publications.
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Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2003 | 0 | 1 | 1 |
2004 | 0 | 1 | 1 |
2007 | 1 | 0 | 1 |
2009 | 1 | 0 | 1 |
2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Interferon Regulatory Factor-1" by people in Profiles.
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Ding R, Sun X, Yi B, Liu W, Kazama K, Xu X, Deshpande DA, Liang C, Sun J. Nur77 Attenuates Inflammasome Activation by Inhibiting Caspase-1 Expression in Pulmonary Vascular Endothelial Cells. Am J Respir Cell Mol Biol. 2021 09; 65(3):288-299.
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Bhandare R, Damera G, Banerjee A, Flammer JR, Keslacy S, Rogatsky I, Panettieri RA, Amrani Y, Tliba O. Glucocorticoid receptor interacting protein-1 restores glucocorticoid responsiveness in steroid-resistant airway structural cells. Am J Respir Cell Mol Biol. 2010 Jan; 42(1):9-15.
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Tliba O, Damera G, Banerjee A, Gu S, Baidouri H, Keslacy S, Amrani Y. Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1. Am J Respir Cell Mol Biol. 2008 Apr; 38(4):463-72.
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Odanagi M, Kikuchi Y, Yamazaki T, Kaneko T, Nakano H, Tamai K, Uitto J, Vitto J, Hanada K. Transcriptional regulation of the 230-kDa bullous pemphigoid antigen gene expression by interferon regulatory factor 1 and interferon regulatory factor 2 in normal human epidermal keratinocytes. Exp Dermatol. 2004 Dec; 13(12):773-9.
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Hoshiya Y, Gupta V, Kawakubo H, Brachtel E, Carey JL, Sasur L, Scott A, Donahoe PK, Maheswaran S. Mullerian inhibiting substance promotes interferon gamma-induced gene expression and apoptosis in breast cancer cells. J Biol Chem. 2003 Dec 19; 278(51):51703-12.
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Manzella L, Gualdi R, Perrotti D, Nicolaides NC, Girlando G, Giuffrida MA, Messina A, Calabretta B. The interferon regulatory factors 1 and 2 bind to a segment of the human c-myb first intron: possible role in the regulation of c-myb expression. Exp Cell Res. 2000 Apr 10; 256(1):248-56.