Proto-Oncogene Proteins c-jun

"Proto-Oncogene Proteins c-jun" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Cellular DNA-binding proteins encoded by the c-jun genes (GENES, JUN). They are involved in growth-related transcriptional control. There appear to be three distinct functions: dimerization (with c-fos), DNA-binding, and transcriptional activation. Oncogenic transformation can take place by constitutive expression of c-jun.

Descriptor ID	D016755
MeSH Number(s)	D12.776.260.108.820 D12.776.624.664.700.182 D12.776.660.763 D12.776.930.127.820
Concept/Terms	Proto-Oncogene Proteins c-jun Proto-Oncogene Proteins c-jun Proto Oncogene Proteins c jun c-jun Proteins c jun Proteins fos-Associated Protein p39 fos Associated Protein p39 jun Proto-Oncogene Product p39 jun Proto Oncogene Product p39 jun Proto-Oncogene Proteins jun Proto Oncogene Proteins p39 c-jun p39 c jun p39(c-jun) Proto-Oncogene Products c-jun Proto Oncogene Products c jun c-fos-Associated Protein p39 c fos Associated Protein p39 Proto-Oncogene Proteins jun Proto Oncogene Proteins jun jun D Proteins jun D Proteins jun B Proteins jun B Proteins

Below are MeSH descriptors whose meaning is more general than "Proto-Oncogene Proteins c-jun".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
Proto-Oncogene Proteins c-jun [D12.776.260.108.820]
Neoplasm Proteins [D12.776.624]
Oncogene Proteins [D12.776.624.664]
Proto-Oncogene Proteins [D12.776.624.664.700]
Proto-Oncogene Proteins c-jun [D12.776.624.664.700.182]
Nuclear Proteins [D12.776.660]
Proto-Oncogene Proteins c-jun [D12.776.660.763]
Transcription Factors [D12.776.930]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
Proto-Oncogene Proteins c-jun [D12.776.930.127.820]

Below are MeSH descriptors whose meaning is related to "Proto-Oncogene Proteins c-jun".

Below are MeSH descriptors whose meaning is more specific than "Proto-Oncogene Proteins c-jun".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Proto-Oncogene Proteins c-jun" by people in this website by year, and whether "Proto-Oncogene Proteins c-jun" was a major or minor topic of these publications.

Bar chart showing 6 publications over 6 distinct years, with a maximum of 1 publications in 2002 and 2007 and 2009 and 2010 and 2015 and 2021

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2007	0	1	1
2009	0	1	1
2010	1	0	1
2015	0	1	1
2021	0	1	1

Below are the most recent publications written about "Proto-Oncogene Proteins c-jun" by people in Profiles.

Arnett A, Moo KG, Flynn KJ, Sundberg TB, Johannessen L, Shamji AF, Gray NS, Decker T, Zheng Y, Gersuk VH, Rahman ZS, Levy DE, Mari? IJ, Linsley PS, Xavier RJ, Khor B. The Cyclin-Dependent Kinase 8 (CDK8) Inhibitor DCA Promotes a Tolerogenic Chemical Immunophenotype in CD4+ T Cells via a Novel CDK8-GATA3-FOXP3 Pathway. Mol Cell Biol. 2021 08 24; 41(9):e0008521.

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Zhang X, Wu H, Dobson JR, Browne G, Hong D, Akech J, Languino LR, Stein GS, Lian JB. Expression of the IL-11 Gene in Metastatic Cells Is Supported by Runx2-Smad and Runx2-cJun Complexes Induced by TGF?1. J Cell Biochem. 2015 Sep; 116(9):2098-108.

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Jiao X, Katiyar S, Willmarth NE, Liu M, Ma X, Flomenberg N, Lisanti MP, Pestell RG. c-Jun induces mammary epithelial cellular invasion and breast cancer stem cell expansion. J Biol Chem. 2010 Mar 12; 285(11):8218-26.

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Ponticos M, Holmes AM, Shi-wen X, Leoni P, Khan K, Rajkumar VS, Hoyles RK, Bou-Gharios G, Black CM, Denton CP, Abraham DJ, Leask A, Lindahl GE. Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen. Arthritis Rheum. 2009 Jul; 60(7):2142-55.

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Boyd JD, Jang H, Shepherd KR, Faherty C, Slack S, Jiao Y, Smeyne RJ. Response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) differs in mouse strains and reveals a divergence in JNK signaling and COX-2 induction prior to loss of neurons in the substantia nigra pars compacta. Brain Res. 2007 Oct 17; 1175:107-16.

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Vietor I, Vadivelu SK, Wick N, Hoffman R, Cotten M, Seiser C, Fialka I, Wunderlich W, Haase A, Korinkova G, Brosch G, Huber LA. TIS7 interacts with the mammalian SIN3 histone deacetylase complex in epithelial cells. EMBO J. 2002 Sep 02; 21(17):4621-31.

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Oberdick J, Schilling K, Smeyne RJ, Corbin JG, Bocchiaro C, Morgan JI. Control of segment-like patterns of gene expression in the mouse cerebellum. Neuron. 1993 Jun; 10(6):1007-18.

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