CCAAT-Enhancer-Binding Proteins

"CCAAT-Enhancer-Binding Proteins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A class of proteins that were originally identified by their ability to bind the DNA sequence CCAAT. The typical CCAAT-enhancer binding protein forms dimers and consists of an activation domain, a DNA-binding basic region, and a leucine-rich dimerization domain (LEUCINE ZIPPERS). CCAAT-BINDING FACTOR is structurally distinct type of CCAAT-enhancer binding protein consisting of a trimer of three different subunits.

Descriptor ID	D022762
MeSH Number(s)	D12.776.260.108.124 D12.776.660.167 D12.776.930.127.124
Concept/Terms	CCAAT-Enhancer-Binding Proteins CCAAT-Enhancer-Binding Proteins CCAAT Enhancer Binding Proteins CAAT-Enhancer Binding Protein Binding Protein, CAAT-Enhancer CAAT Enhancer Binding Protein CCAAT-Enhancer-Binding Protein CCAAT Enhancer Binding Protein C-EBP Protein C EBP Protein C-EBP Nuclear Protein C EBP Nuclear Protein Nuclear Protein, C-EBP CAAT-Enhancer-Binding Proteins CAAT Enhancer Binding Proteins C-EBP Proteins C EBP Proteins CCAAT Sequence-Specific DNA-Binding Proteins CCAAT Sequence Specific DNA Binding Proteins Nuclear Protein C-EBP C-EBP, Nuclear Protein Nuclear Protein C EBP

Below are MeSH descriptors whose meaning is more general than "CCAAT-Enhancer-Binding Proteins".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
Basic-Leucine Zipper Transcription Factors [D12.776.260.108]
CCAAT-Enhancer-Binding Proteins [D12.776.260.108.124]
Nuclear Proteins [D12.776.660]
CCAAT-Enhancer-Binding Proteins [D12.776.660.167]
Transcription Factors [D12.776.930]
Basic-Leucine Zipper Transcription Factors [D12.776.930.127]
CCAAT-Enhancer-Binding Proteins [D12.776.930.127.124]

Below are MeSH descriptors whose meaning is related to "CCAAT-Enhancer-Binding Proteins".

Below are MeSH descriptors whose meaning is more specific than "CCAAT-Enhancer-Binding Proteins".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "CCAAT-Enhancer-Binding Proteins" by people in this website by year, and whether "CCAAT-Enhancer-Binding Proteins" was a major or minor topic of these publications.

Bar chart showing 7 publications over 5 distinct years, with a maximum of 2 publications in 1998 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1998	2	0	2
2001	0	1	1
2008	0	1	1
2010	0	1	1
2020	1	1	2

Below are the most recent publications written about "CCAAT-Enhancer-Binding Proteins" by people in Profiles.

Kwak T, Wang F, Deng H, Condamine T, Kumar V, Perego M, Kossenkov A, Montaner LJ, Xu X, Xu W, Zheng C, Schuchter LM, Amaravadi RK, Mitchell TC, Karakousis GC, Mulligan C, Nam B, Masters G, Hockstein N, Bennett J, Nefedova Y, Gabrilovich DI. Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer. Cell Rep. 2020 12 29; 33(13):108571.

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Reardon ES, Shukla V, Xi S, Gara SK, Liu Y, Straughan D, Zhang M, Hong JA, Payabyab EC, Kumari A, Richards WG, De Rienzo A, Hassan R, Miettinen M, Xi L, Raffeld M, Uechi LT, Li X, Wang R, Chen H, Hoang CD, Bueno R, Schrump DS. UHRF1 Is a Novel Druggable Epigenetic Target in Malignant Pleural Mesothelioma. J Thorac Oncol. 2021 01; 16(1):89-103.

View in: PubMed
La Rocca G, Shi B, Audia A, Ferrari-Amorotti G, Mellert HS, Calabretta B, McMahon SB, Sepp-Lorenzino L, Baserga R. Regulation of microRNA-145 by growth arrest and differentiation. Exp Cell Res. 2011 Feb 15; 317(4):488-95.

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Hashimoto H, Horton JR, Zhang X, Bostick M, Jacobsen SE, Cheng X. The SRA domain of UHRF1 flips 5-methylcytosine out of the DNA helix. Nature. 2008 Oct 09; 455(7214):826-9.

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Frank PG, Galbiati F, Volonte D, Razani B, Cohen DE, Marcel YL, Lisanti MP. Influence of caveolin-1 on cellular cholesterol efflux mediated by high-density lipoproteins. Am J Physiol Cell Physiol. 2001 May; 280(5):C1204-14.

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Artlett CM, Chen SJ, Varga J, Jimenez SA. Modulation of basal expression of the human alpha1(I) procollagen gene (COL1A1) by tandem NF-1/Sp1 promoter elements in normal human dermal fibroblasts. Matrix Biol. 1998 Oct; 17(6):425-34.

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Chen SJ, Artlett CM, Jimenez SA, Varga J. Modulation of human alpha1(I) procollagen gene activity by interaction with Sp1 and Sp3 transcription factors in vitro. Gene. 1998 Jul 17; 215(1):101-10.

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Li LH, Nerlov C, Prendergast G, MacGregor D, Ziff EB. c-Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II. EMBO J. 1994 Sep 01; 13(17):4070-9.

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