"Protein Kinase C-delta" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A ubiquitously expressed protein kinase that is involved in a variety of cellular SIGNAL PATHWAYS. Its activity is regulated by a variety of signaling protein tyrosine kinase.
| Descriptor ID |
D051745
|
| MeSH Number(s) |
D08.811.913.696.620.682.700.725.400
|
| Concept/Terms |
Protein Kinase C-delta- Protein Kinase C-delta
- Kinase C-delta, Protein
- Protein Kinase C delta
- PKC-delta Serine-Threonine Kinase
- PKC delta Serine Threonine Kinase
- Serine-Threonine Kinase, PKC-delta
|
Below are MeSH descriptors whose meaning is more general than "Protein Kinase C-delta".
Below are MeSH descriptors whose meaning is more specific than "Protein Kinase C-delta".
This graph shows the total number of publications written about "Protein Kinase C-delta" by people in this website by year, and whether "Protein Kinase C-delta" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 1 | 1 |
| 2011 | 2 | 0 | 2 |
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Below are the most recent publications written about "Protein Kinase C-delta" by people in Profiles.
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Wermuth PJ, Addya S, Jimenez SA. Effect of protein kinase C delta (PKC-d) inhibition on the transcriptome of normal and systemic sclerosis human dermal fibroblasts in vitro. PLoS One. 2011; 6(11):e27110.
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Li Z, Jimenez SA. Protein kinase Cd and c-Abl kinase are required for transforming growth factor ? induction of endothelial-mesenchymal transition in vitro. Arthritis Rheum. 2011 Aug; 63(8):2473-83.
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Xiao L, Eto M, Kazanietz MG. ROCK mediates phorbol ester-induced apoptosis in prostate cancer cells via p21Cip1 up-regulation and JNK. J Biol Chem. 2009 Oct 23; 284(43):29365-75.
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Ricchiuti V, Lian CG, Oestreicher EM, Tran L, Stone JR, Yao T, Seely EW, Williams GH, Adler GK. Estradiol increases angiotensin II type 1 receptor in hearts of ovariectomized rats. J Endocrinol. 2009 Jan; 200(1):75-84.
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Tanaka M, Terry RD, Mokhtari GK, Inagaki K, Koyanagi T, Kofidis T, Mochly-Rosen D, Robbins RC. Suppression of graft coronary artery disease by a brief treatment with a selective epsilonPKC activator and a deltaPKC inhibitor in murine cardiac allografts. Circulation. 2004 Sep 14; 110(11 Suppl 1):II194-9.
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Kucich U, Rosenbloom JC, Abrams WR, Rosenbloom J. Transforming growth factor-beta stabilizes elastin mRNA by a pathway requiring active Smads, protein kinase C-delta, and p38. Am J Respir Cell Mol Biol. 2002 Feb; 26(2):183-8.
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Jimenez SA, Gaidarova S, Saitta B, Sandorfi N, Herrich DJ, Rosenbloom JC, Kucich U, Abrams WR, Rosenbloom J. Role of protein kinase C-delta in the regulation of collagen gene expression in scleroderma fibroblasts. J Clin Invest. 2001 Nov; 108(9):1395-403.
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Kucich U, Rosenbloom JC, Shen G, Abrams WR, Hamilton AD, Sebti SM, Rosenbloom J. TGF-beta1 stimulation of fibronectin transcription in cultured human lung fibroblasts requires active geranylgeranyl transferase I, phosphatidylcholine-specific phospholipase C, protein kinase C-delta, and p38, but not erk1/erk2. Arch Biochem Biophys. 2000 Feb 15; 374(2):313-24.