"Basigin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A widely distributed cell surface transmembrane glycoprotein characterized by extracellular IMMUNOGLOBULIN DOMAINS. It stimulates the synthesis of MATRIX METALLOPROTEINASES and is found at high levels on the surface of malignant NEOPLASMS where it may play a role as a mediator of malignant cell behavior.
| Descriptor ID |
D051926
|
| MeSH Number(s) |
D12.776.395.550.045 D12.776.543.550.187 D23.050.285.040
|
| Concept/Terms |
Basigin- Basigin
- Emmprin
- CD147 Antigens
- Extracellular Matrix Metalloproteinase Inducer (EMMPRIN)
- Emmprin Protein
- Basigin Protein
- CD147 Antigen
- Antigen, CD147
- Antigens, CD147
|
Below are MeSH descriptors whose meaning is more general than "Basigin".
Below are MeSH descriptors whose meaning is more specific than "Basigin".
This graph shows the total number of publications written about "Basigin" by people in this website by year, and whether "Basigin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 1 | 0 | 1 |
| 2012 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Basigin" by people in Profiles.
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Pourani MR, Nekooghadam SM, Youssefian L, Vahidnezhad H, Abdollahimajd F. CD147 inhibitors as a treatment for melanoma: Promising agents against SARS-CoV-2 infection. Dermatol Ther. 2020 Nov; 33(6):e14449.
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Dai L, Guinea MC, Slomiany MG, Bratoeva M, Grass GD, Tolliver LB, Maria BL, Toole BP. CD147-dependent heterogeneity in malignant and chemoresistant properties of cancer cells. Am J Pathol. 2013 Feb; 182(2):577-85.
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Slomiany MG, Grass GD, Robertson AD, Yang XY, Maria BL, Beeson C, Toole BP. Hyaluronan, CD44, and emmprin regulate lactate efflux and membrane localization of monocarboxylate transporters in human breast carcinoma cells. Cancer Res. 2009 Feb 15; 69(4):1293-301.
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Maria BL, Gupta N, Gilg AG, Abdel-Wahab M, Leonard AP, Slomiany M, Wheeler WG, Tolliver LB, Babcock MA, Lucas JT, Toole BP. Targeting hyaluronan interactions in spinal cord astrocytomas and diffuse pontine gliomas. J Child Neurol. 2008 Oct; 23(10):1214-20.
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Gabison EE, Hoang-Xuan T, Mauviel A, Menashi S. EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair. Biochimie. 2005 Mar-Apr; 87(3-4):361-8.
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Gabison EE, Mourah S, Steinfels E, Yan L, Hoang-Xuan T, Watsky MA, De Wever B, Calvo F, Mauviel A, Menashi S. Differential expression of extracellular matrix metalloproteinase inducer (CD147) in normal and ulcerated corneas: role in epithelio-stromal interactions and matrix metalloproteinase induction. Am J Pathol. 2005 Jan; 166(1):209-19.