Transcription Factor RelA

"Transcription Factor RelA" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

A subunit of NF-kappa B that is primarily responsible for its transactivation function. It contains a C-terminal transactivation domain and an N-terminal domain with homology to PROTO-ONCOGENE PROTEINS C-REL.

Descriptor ID	D051996
MeSH Number(s)	D12.776.260.600.249 D12.776.660.600.249 D12.776.930.600.249
Concept/Terms	Transcription Factor RelA Transcription Factor RelA RelA, Transcription Factor NF-kappa B p65 NF kappa B p65 p65, NF-kappa B NF-kappa B p65 Subunit NF kappa B p65 Subunit Transcription Factor p65 p65, Transcription Factor p65 Transcription Factor Transcription Factor, p65 v-Rel Reticuloendotheliosis Viral Oncogene Homolog A v Rel Reticuloendotheliosis Viral Oncogene Homolog A NF-kappaB 65-kDa NF kappaB 65 kDa

Below are MeSH descriptors whose meaning is more general than "Transcription Factor RelA".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Proteins [D12.776]
DNA-Binding Proteins [D12.776.260]
NF-kappa B [D12.776.260.600]
Transcription Factor RelA [D12.776.260.600.249]
Nuclear Proteins [D12.776.660]
NF-kappa B [D12.776.660.600]
Transcription Factor RelA [D12.776.660.600.249]
Transcription Factors [D12.776.930]
NF-kappa B [D12.776.930.600]
Transcription Factor RelA [D12.776.930.600.249]

Below are MeSH descriptors whose meaning is related to "Transcription Factor RelA".

Below are MeSH descriptors whose meaning is more specific than "Transcription Factor RelA".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Transcription Factor RelA" by people in this website by year, and whether "Transcription Factor RelA" was a major or minor topic of these publications.

Bar chart showing 11 publications over 8 distinct years, with a maximum of 3 publications in 2008

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2002	0	1	1
2003	0	1	1
2005	0	1	1
2006	0	2	2
2007	0	1	1
2008	0	3	3
2010	1	0	1
2011	0	1	1

Below are the most recent publications written about "Transcription Factor RelA" by people in Profiles.

Wang J, Markova D, Anderson DG, Zheng Z, Shapiro IM, Risbud MV. TNF-a and IL-1ß promote a disintegrin-like and metalloprotease with thrombospondin type I motif-5-mediated aggrecan degradation through syndecan-4 in intervertebral disc. J Biol Chem. 2011 Nov 18; 286(46):39738-49.

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Alvarez-Guardia D, Palomer X, Coll T, Davidson MM, Chan TO, Feldman AM, Laguna JC, Vázquez-Carrera M. The p65 subunit of NF-kappaB binds to PGC-1alpha, linking inflammation and metabolic disturbances in cardiac cells. Cardiovasc Res. 2010 Aug 1; 87(3):449-58.

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Taccioli C, Wan SG, Liu CG, Alder H, Volinia S, Farber JL, Croce CM, Fong LY. Zinc replenishment reverses overexpression of the proinflammatory mediator S100A8 and esophageal preneoplasia in the rat. Gastroenterology. 2009 Mar; 136(3):953-66.

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Han S, Ritzenthaler JD, Zheng Y, Roman J. PPARbeta/delta agonist stimulates human lung carcinoma cell growth through inhibition of PTEN expression: the involvement of PI3K and NF-kappaB signals. Am J Physiol Lung Cell Mol Physiol. 2008 Jun; 294(6):L1238-49.

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Fong LY, Jiang Y, Riley M, Liu X, Smalley KJ, Guttridge DC, Farber JL. Prevention of upper aerodigestive tract cancer in zinc-deficient rodents: inefficacy of genetic or pharmacological disruption of COX-2. Int J Cancer. 2008 Mar 1; 122(5):978-89.

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Tone Y, Kojima Y, Furuuchi K, Brady M, Yashiro-Ohtani Y, Tykocinski ML, Tone M. OX40 gene expression is up-regulated by chromatin remodeling in its promoter region containing Sp1/Sp3, YY1, and NF-kappa B binding sites. J Immunol. 2007 Aug 1; 179(3):1760-7.

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Ren Q, Kari C, Quadros MR, Burd R, McCue P, Dicker AP, Rodeck U. Malignant transformation of immortalized HaCaT keratinocytes through deregulated nuclear factor kappaB signaling. Cancer Res. 2006 May 15; 66(10):5209-15.

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Muthumani K, Choo AY, Zong WX, Madesh M, Hwang DS, Premkumar A, Thieu KP, Emmanuel J, Kumar S, Thompson CB, Weiner DB. The HIV-1 Vpr and glucocorticoid receptor complex is a gain-of-function interaction that prevents the nuclear localization of PARP-1. Nat Cell Biol. 2006 Feb; 8(2):170-9.

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Domingo-Domenech J, Mellado B, Ferrer B, Truan D, Codony-Servat J, Sauleda S, Alcover J, Campo E, Gascon P, Rovira A, Ross JS, Fernández PL, Albanell J. Activation of nuclear factor-kappaB in human prostate carcinogenesis and association to biochemical relapse. Br J Cancer. 2005 Nov 28; 93(11):1285-94.

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Debierre-Grockiego F, Azzouz N, Schmidt J, Dubremetz JF, Geyer H, Geyer R, Weingart R, Schmidt RR, Schwarz RT. Roles of glycosylphosphatidylinositols of Toxoplasma gondii. Induction of tumor necrosis factor-alpha production in macrophages. J Biol Chem. 2003 Aug 29; 278(35):32987-93.

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