"Ectodysplasins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Transmembrane proteins belonging to the tumor necrosis factor superfamily that play an essential role in the normal development of several ectodermally derived organs. Several isoforms of the ectodysplasins exist due to multiple ALTERNATIVE SPLICING of the MRNA for the protein. The isoforms ectodysplasin A1 and ectodysplasin A2 are considered biologically active and each bind distinct ECTODYSPLASIN RECEPTORS. Genetic mutations that result in loss of function of ectodysplasin result in ECTODERMAL DYSPLASIA 1, ANHIDROTIC.
| Descriptor ID |
D053331
|
| MeSH Number(s) |
D12.644.276.374.750.186 D12.776.395.550.275 D12.776.467.374.750.186 D12.776.543.550.275 D23.529.374.750.186
|
| Concept/Terms |
Ectodysplasins- Ectodysplasins
- Ectodysplasin-A
- Ectodysplasin A
- Ectodysplasin
|
Below are MeSH descriptors whose meaning is more general than "Ectodysplasins".
Below are MeSH descriptors whose meaning is more specific than "Ectodysplasins".
This graph shows the total number of publications written about "Ectodysplasins" by people in this website by year, and whether "Ectodysplasins" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2002 | 0 | 1 | 1 |
| 2008 | 0 | 1 | 1 |
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Below are the most recent publications written about "Ectodysplasins" by people in Profiles.
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Elliott MB, Barr AE, Kietrys DM, Al-Shatti T, Amin M, Barbe MF. Peripheral neuritis and increased spinal cord neurochemicals are induced in a model of repetitive motion injury with low force and repetition exposure. Brain Res. 2008 Jul 7; 1218:103-13.
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Bacher M, Weihe E, Dietzschold B, Meinhardt A, Vedder H, Gemsa D, Bette M. Borna disease virus-induced accumulation of macrophage migration inhibitory factor in rat brain astrocytes is associated with inhibition of macrophage infiltration. Glia. 2002 Mar 15; 37(4):291-306.