"beta 2-Glycoprotein I" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A 44-kDa highly glycosylated plasma protein that binds phospholipids including CARDIOLIPIN; APOLIPOPROTEIN E RECEPTOR; membrane phospholipids, and other anionic phospholipid-containing moieties. It plays a role in coagulation and apoptotic processes. Formerly known as apolipoprotein H, it is an autoantigen in patients with ANTIPHOSPHOLIPID ANTIBODIES.
| Descriptor ID |
D053482
|
| MeSH Number(s) |
D12.776.124.117 D12.776.395.195
|
| Concept/Terms |
beta 2-Glycoprotein I- beta 2-Glycoprotein I
- beta 2 Glycoprotein I
- Apo H
- Endothelial Cell-Viability Maintaining Factor
- Endothelial Cell Viability Maintaining Factor
- beta(2)GPI
- beta2-Glycoprotein I
- beta2 Glycoprotein I
- EC-VMFa
- EC VMFa
- Anticardiolipin Cofactor
- Cofactor, Anticardiolipin
- Apolipoprotein H
|
Below are MeSH descriptors whose meaning is more general than "beta 2-Glycoprotein I".
Below are MeSH descriptors whose meaning is more specific than "beta 2-Glycoprotein I".
This graph shows the total number of publications written about "beta 2-Glycoprotein I" by people in this website by year, and whether "beta 2-Glycoprotein I" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2014 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2025 | 2 | 0 | 2 |
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Below are the most recent publications written about "beta 2-Glycoprotein I" by people in Profiles.
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Kulkarni PP, Alluri RK, Godwin M, Forbes GL, Merkulova A, Lambert S, Vijay A, Palihati M, Kundu S, Shim YJ, Kalonji K, Schmaier AH, Holinstat M, Cameron SJ, McCrae KR. Protection of ?2GPI-deficient mice from thrombosis reflects a defect in PAR3-facilitated platelet activation. Blood. 2025 May 01; 145(18):2086-2099.
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Effendi MUN, Majid H, Moiz B, Jafri L, Zehra N, Khan AH. Unveiling the clinical spectrum: Exploring the role of anti-?2glycoprotein-1 antibodies (anti-?2GPI) in antiphospholipid syndrome suspects. Int J Immunopathol Pharmacol. 2025 Jan-Dec; 39:3946320251316724.
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Gupta A, Johnson DH, Nagalla S. Antiphospholipid Antibodies. JAMA. 2017 Sep 12; 318(10):959-960.
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Amirkhosravi A, Boulaftali Y, Robles-Carrillo L, Meyer T, McKenzie SE, Francis JL, Bergmeier W. CalDAG-GEFI deficiency protects mice from Fc?RIIa-mediated thrombotic thrombocytopenia induced by CD40L and ?2GPI immune complexes. J Thromb Haemost. 2014 Dec; 12(12):2113-9.
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Cimaz R, Romeo A, Scarano A, Avcin T, Viri M, Veggiotti P, Gatti A, Lodi M, Catelli L, Panzeri P, Cecchini G, Meroni PL. Prevalence of anti-cardiolipin, anti-beta2 glycoprotein I, and anti-prothrombin antibodies in young patients with epilepsy. Epilepsia. 2002 Jan; 43(1):52-9.
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Subang R, Levine JS, Janoff AS, Davidson SM, Taraschi TF, Koike T, Minchey SR, Whiteside M, Tannenbaum M, Rauch J. Phospholipid-bound beta 2-glycoprotein I induces the production of anti-phospholipid antibodies. J Autoimmun. 2000 Aug; 15(1):21-32.